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In Vivo 毒性試験の世界市場:製品別、毒性エンドポイント別2025年予測

In Vivo Toxicology Market by Product (Animal Models, Reagents & Kits), Test Type (Chronic, Sub-acute), Toxicity Endpoints (Systemic, Immunotoxicity), Testing Facility (Outsourced, In-house), End User (Academic & Research Institute, CROs) - Forecast to 2025

出版元:MarketsandMarketsLinkIcon出版元について
発行年:2021年3月
定価 Single User License(1名様ライセンス)US$4,950(米国ドル)/Multi User License(5名様)$6,650 /Corporate User License $8,150
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納品形態:PDF by Email
当調査レポートは英文264ページになります。
商品コード:MAM2387

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【レポート紹介】
In Vivo毒性試験の世界市場規模は、2020年で50億ドル、2025年には66億ドルへと漸増する見通しです。レポートはIn vivo毒性試験の世界市場について2025年までの市場予測データ(金額US$)を掲載しています。また市場をさまざまな切り口で細分化し、そのセグメント市場ごとの市場予測を中心に構成されています。当レポートでの各種セグメント市場の区分は、製品別市場、試験タイプ別市場、試験施設別市場、毒性エンドポイント別市場、エンドユーザー別市場および主要国地域別市場、などとなっています。また競合状況、主要企業情報(17社)、COVID-19によるIn vivo毒性試験市場への影響、特許分析などの分析情報も加味し、In vivo毒性試験市場の今後成長性および動向を詳細にレポートしています。

【レポート構成概要】
◆In vivo毒性試験の世界市場予測2018-2025年
・市場規模(US$)

◆製品別、市場-2025年
消耗品
・試薬/キット
・動物モデル
-マウスモデル
-ラットモデル
-その他動物モデル
器具
※(市場規模US$)

◆試験タイプ別、市場-2025年
・慢性毒性試験
・亜慢性毒性試験
・亜急性毒性試験
・急性毒性試験
※(市場規模US$)

◆試験施設別、市場-2025年
・外部委託試験施設
・社内試験施設
※(市場規模US$)

◆毒性エンドポイント別、市場-2025年
・免疫毒性
・全身毒性
・発がん性
・遺伝子毒性
・生殖発生毒性
・その他
※(市場規模US$)

◆エンドユーザー別、市場-2025年
・学術研究機関
・製薬/バイオテクノロジー企業
・受託研究機関(CRO)
・その他
※(市場規模US$)

◆主要国地域別市場-2025年
北米
・米国、カナダ
欧州
・英国、フランス、ドイツ、イタリア、スペイン
・その他欧州
アジア太平洋
・日本、中国、インド
・その他アジア太平洋
中南米
・ブラジル、メキシコ
・その他中南米
中東アフリカ
※国地域別に全セグメント別の細分化データ掲載、詳細は目次参照

◆市場分析
・市場ダイナミクス(ドライバー、障壁、機会、課題)
・COVID-19によるIn vivo毒性試験市場への影響
・特許分析
・ファイブフォース分析
・サプライチェーン分析
・バリューチェーン分析
・市場シェア分析-2019年
・競合状況

◆In vivo毒性試験の主要企業プロフィール動向
・CHARLES RIVER LABORATORIES       
・THE JACKSON LABORATORY
・ENVIGO        
・TACONIC BIOSCIENCES         
・GENOWAY    
・HARBOUR BIOMED   
・CROWN BIOSCIENCE
・TRANSCURE BIOSERVICES    
・OZGENE PTY LTD.    
・THERMO FISHER SCIENTIFIC
・DANAHER CORPORATION    
・AGILENT TECHNOLOGIES    
・WATERS CORPORATION       
・株式会社島津製作所
・BIO-RAD LABORATORIES      
・BRUKER CORPORATION        
・PERKINELMER           

(その他企業)
・MERCK KGAA
・GE HEALTHCARE      
・JANVIER LABS            
・INGENIOUS TARGETING LABORATORY         
・POLYGENE   
・GVK BIO        
・CYAGEN BIOSCIENCES           
・DATA SCIENCES INTERNATIONAL    

(全264頁)



【レポート詳細目次、データ項目一覧は当ページ下を参照ください】

英文詳細目次(table of contents)

【原文詳細目次】

In Vivo Toxicology Market by Product (Animal Models, Reagents & Kits), Test Type (Chronic, Sub-acute), Toxicity Endpoints (Systemic, Immunotoxicity), Testing Facility (Outsourced, In-house), End User (Academic & Research Institute, CROs) - Forecast to 2025

Table of Contents

1            INTRODUCTION            38

1.1         OBJECTIVES OF THE STUDY      38
1.2         MARKET DEFINITION   38
1.2.1      INCLUSIONS & EXCLUSIONS OF THE STUDY      38
1.3         MARKET SCOPE             39
1.3.1      MARKETS COVERED     39
・       FIGURE 1          IN VIVO TOXICOLOGY MARKET SEGMENTATION              39
1.3.2      YEARS CONSIDERED FOR THE STUDY   40
1.4         CURRENCY        40
1.5         LIMITATIONS   40
1.6         STAKEHOLDERS            40
1.7         SUMMARY OF CHANGES            41

2            RESEARCH METHODOLOGY     42

2.1         RESEARCH DATA           42
2.1.1      SECONDARY DATA       42
2.1.2      PRIMARY DATA 43
・       FIGURE 2          BREAKDOWN OF PRIMARIES: IN VIVO TOXICOLOGY MARKET            43
2.1.3      MARKET DATA ESTIMATION & TRIANGULATION          44
・       FIGURE 3          DATA TRIANGULATION METHODOLOGY         44
2.2         MARKET ESTIMATION METHODOLOGY            45
・       FIGURE 4          MARKET SIZE ESTIMATION (COMPANY REVENUE ANALYSIS-BASED ESTIMATION)             45
・       FIGURE 5          IN VIVO TOXICOLOGY MARKET SIZE (USD MILLION)              45
・       FIGURE 6          IN VIVO TOXICOLOGY MARKET: GROWTH RATE OF TOP COMPANIES (2017−2019)  46
・       FIGURE 7          IN VIVO TOXICOLOGY MARKET: FINAL CAGR PROJECTIONS (2020−2025)       46
・       FIGURE 8          IN VIVO TOXICOLOGY MARKET: CAGR PROJECTIONS FROM THE ANALYSIS OF DEMAND-SIDE DRIVERS AND OPPORTUNITIES              47
2.3         INDUSTRY INSIGHTS    48
2.4         ASSUMPTIONS FOR THE STUDY             48

3            EXECUTIVE SUMMARY 49

・       FIGURE 9         IN VIVO TOXICOLOGY MARKET, BY PRODUCT, 2020 VS. 2025 (USD MILLION)     49
・       FIGURE 10        IN VIVO TOXICOLOGY MARKET, BY TEST TYPE, 2020 VS. 2025 (USD MILLION)             50
・       FIGURE 11        GEOGRAPHICAL SNAPSHOT OF THE IN VIVO TOXICOLOGY MARKET 51

4            PREMIUM INSIGHTS      52

4.1         IN VIVO TOXICOLOGY MARKET OVERVIEW      52
・       FIGURE 12        INCREASING PHARMACEUTICAL R&D ACTIVITIES TO DRIVE MARKET GROWTH          52
4.2         IN VIVO TOXICOLOGY MARKET SHARE, BY TOXICITY ENDPOINT, 2020 VS. 2025 52
・       FIGURE 13        IMMUNOTOXICITY SEGMENT TO ACCOUNT FOR THE LARGEST MARKET SHARE IN 2025          52
4.3         IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY, 2020 VS. 2025 (USD MILLION) 53
・       FIGURE 14        OUTSOURCED TESTING FACILITIES SEGMENT TO REGISTER THE HIGHEST GROWTH IN THE FORECAST PERIOD 53
4.4         IN VIVO TOXICOLOGY MARKET SHARE, BY END USER, 2020 VS. 2025              53
・       FIGURE 15        ACADEMIC & RESEARCH INSTITUTES ARE THE LARGEST END USERS OF IN VIVO TOXICOLOGY PRODUCTS     53

5            MARKET OVERVIEW     54

5.1         MARKET DYNAMICS     54
・       FIGURE 16        IN VIVO TOXICOLOGY MARKET: DRIVERS, RESTRAINTS, OPPORTUNITIES, AND CHALLENGES       54
5.1.1      DRIVERS            55
5.1.1.1   INCREASING PHARMACEUTICAL R&D ACTIVITIES         55
・       TABLE 1           R&D INVESTMENTS OF NOTE   55
5.1.1.2   INNOVATIONS IN ANIMAL MODELS      56
・       TABLE 2           INNOVATIVE ANIMAL MODELS DEVELOPED AND LAUNCHED BY PLAYERS            56
5.1.1.3   EXCLUSIVE IN VIVO TOXICOLOGY TESTS          56
5.1.1.4   INCREASING DEMAND FOR PERSONALIZED MEDICINE 57
5.1.2      RESTRAINTS     57
5.1.2.1   ALTERNATIVES TO ANIMAL TESTING   57
5.1.3      OPPORTUNITIES           58
5.1.3.1   RISING DEMAND FOR HUMANIZED ANIMAL MODELS   58
5.1.4      CHALLENGES   58
5.1.4.1   REGULATIONS AND LAWS FOR THE ETHICAL USE OF ANIMALS IN RESEARCH        58
5.2         IMPACT OF COVID-19 ON THE VIVO TOXICOLOGY MARKET     59
5.3         REGULATORY ASSESSMENT      59
5.3.1      INTRODUCTION            59
5.3.2      NORTH AMERICA          59
5.3.3      EUROPE             60
5.3.4      CHINA  61
5.3.5      JAPAN  62
5.3.6      INDIA   62
5.3.7      AUSTRALIA       63
5.3.8      BRAZIL 63
5.4         PATENT ANALYSIS        64
5.4.1      TOP EIGHT INSTITUTES WITH THE HIGHEST NO. OF PATENT FILINGS FOR ANIMAL MODELS IN THE LAST 10 YEARS   64
5.4.2      TOP 20 ACTIVE COUNTRIES IN PATENT FILING (ANIMAL MODELS) IN THE LAST 10 YEARS       64
5.4.3      FIELD OF STUDY IN PATENT FILING (ANIMAL MODELS) IN THE LAST 10 YEARS           65
5.5         TRADE ANALYSIS          65
5.5.1      TRADE ANALYSIS FOR CHROMATOGRAPHY AND ELECTROPHORESIS INSTRUMENTS 65
・       TABLE 3           IMPORT DATA FOR ELECTROPHORESIS AND CHROMATOGRAPHY INSTRUMENTS, BY COUNTRY, 2016–2020 (USD THOUSAND)     66
5.5.2      TRADE ANALYSIS FOR DIAGNOSTIC AND LABORATORY REAGENTS              67
・       TABLE 4           IMPORT DATA FOR DIAGNOSTIC AND LABORATORY REAGENTS, BY COUNTRY, 2016-2020 (USD THOUSAND) 67
5.6         PORTER’S FIVE FORCES ANALYSIS         68
・       TABLE 5           PORTER’S FIVE FORCES ANALYSIS         68
5.6.1      THREAT OF NEW ENTRANTS    68
5.6.2      THREAT OF SUBSTITUTES         68
5.6.3      BARGAINING POWER OF SUPPLIERS     69
5.6.4      BARGAINING POWER OF BUYERS           69
5.6.5      INTENSITY OF COMPETITIVE RIVALRY 69
5.7         SUPPLY CHAIN ANALYSIS          69
・       FIGURE 17        DIRECT DISTRIBUTION STRATEGY PREFERRED BY PROMINENT COMPANIES          70
5.7.1      KEY INFLUENCERS        70
5.8         VALUE CHAIN ANALYSIS            71
・       FIGURE 18        MAJOR VALUE IS ADDED DURING THE MANUFACTURING
AND ASSEMBLY PHASES             71
5.9         ECOSYSTEM ANALYSIS OF THE IN VIVO TOXICOLOGY MARKET              72
・       FIGURE 19        ECOSYSTEM ANALYSIS 72

6            IN VIVO TOXICOLOGY MARKET, BY PRODUCT 73

6.1         INTRODUCTION            74
・       TABLE 6           IN VIVO TOXICOLOGY MARKET, BY PRODUCT, 2018–2025 (USD MILLION)     74
6.2         CONSUMABLES 74
・       TABLE 7           IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES, BY TYPE,
2018–2025 (USD MILLION)          74
・       TABLE 8           IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES, BY REGION,
2018–2025 (USD MILLION)          75
・       TABLE 9           NORTH AMERICA: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES,
BY COUNTRY, 2018–2025 (USD MILLION)            75
・       TABLE 10         EUROPE: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES, BY COUNTRY, 2018–2025 (USD MILLION)          75
・       TABLE 11         ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES,
BY COUNTRY, 2018–2025 (USD MILLION)            76
・       TABLE 12         LATIN AMERICA: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES,
BY COUNTRY, 2018–2025 (USD MILLION)            76
6.2.1      REAGENTS & KITS          76
6.2.1.1   REAGENTS & KITS HOLD THE LARGEST SHARE OF THE CONSUMABLES MARKET            76
・       TABLE 13        IN VIVO TOXICOLOGY MARKET FOR REAGENTS & KITS, BY REGION,
2018–2025 (USD MILLION)          77
・       TABLE 14         NORTH AMERICA: IN VIVO TOXICOLOGY MARKET FOR REAGENTS & KITS,
BY COUNTRY, 2018–2025 (USD MILLION)            77
・       TABLE 15         EUROPE: IN VIVO TOXICOLOGY MARKET FOR REAGENTS & KITS, BY COUNTRY, 2018–2025 (USD MILLION)      77
・       TABLE 16         ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET FOR REAGENTS & KITS,
BY COUNTRY, 2018–2025 (USD MILLION)            78
・       TABLE 17         LATIN AMERICA: IN VIVO TOXICOLOGY MARKET FOR REAGENTS & KITS,
BY COUNTRY, 2018–2025 (USD MILLION)            78
6.2.2      ANIMAL MODELS          78
・       TABLE 18        IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE,
2018–2025 (USD MILLION)          79
・       TABLE 19        IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY REGION,
2018–2025 (USD MILLION)          79
・       TABLE 20         NORTH AMERICA: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS,
BY COUNTRY, 2018–2025 (USD MILLION)            79
・       TABLE 21         EUROPE: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY COUNTRY, 2018–2025 (USD MILLION)        80
・       TABLE 22         ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS,
BY COUNTRY, 2018–2025 (USD MILLION)            80
・       TABLE 23         LATIN AMERICA: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS,
BY COUNTRY, 2018–2025 (USD MILLION)            80
6.2.2.1   MICE MODELS 81
6.2.2.1.1 MICE MODELS ARE WIDELY USED IN IN VIVO TOXICITY TESTING              81
・       TABLE 24         PROMINENT MICE MODELS AVAILABLE IN THE MARKET            81
・       TABLE 25         IN VIVO TOXICOLOGY MARKET FOR MICE MODELS, BY REGION,
2018–2025 (USD MILLION)          82
・       TABLE 26         NORTH AMERICA: IN VIVO TOXICOLOGY MARKET FOR MICE MODELS,
BY COUNTRY, 2018–2025 (USD MILLION)            82
・       TABLE 27         EUROPE: IN VIVO TOXICOLOGY MARKET FOR MICE MODELS, BY COUNTRY, 2018–2025 (USD MILLION)        82
・       TABLE 28         ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET FOR MICE MODELS,
BY COUNTRY, 2018–2025 (USD MILLION)            83
・       TABLE 29         LATIN AMERICA: IN VIVO TOXICOLOGY MARKET FOR MICE MODELS,
BY COUNTRY, 2018–2025 (USD MILLION)            83
6.2.2.2   RAT MODELS   83
6.2.2.2.1 EASE OF PERFORMING SURGERY ON RAT MODELS AND DEVELOPMENT OF GENETICALLY MODIFIED RAT MODELS DRIVE THE MARKET            83
・       TABLE 30         IN VIVO TOXICOLOGY MARKET FOR RAT MODELS, BY REGION,
2018–2025 (USD MILLION)          84
・       TABLE 31         NORTH AMERICA: IN VIVO TOXICOLOGY MARKET FOR RAT MODELS,
BY COUNTRY, 2018–2025 (USD MILLION)            84
・       TABLE 32         EUROPE: IN VIVO TOXICOLOGY MARKET FOR RAT MODELS, BY COUNTRY, 2018–2025 (USD MILLION)        85
・       TABLE 33         ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET FOR RAT MODELS, BY COUNTRY, 2018–2025 (USD MILLION) 85
・       TABLE 34         LATIN AMERICA: IN VIVO TOXICOLOGY MARKET FOR RAT MODELS,
BY COUNTRY, 2018–2025 (USD MILLION)            85
6.2.2.3   OTHER ANIMAL MODELS          86
・       TABLE 35         GUINEA PIG AND HAMSTER MODELS: ADVANTAGES AND USAGE      86
・       TABLE 36         NON-RODENT ANIMAL MODELS: ADVANTAGES AND USAGE 87
・       TABLE 37         IN VIVO TOXICOLOGY MARKET FOR OTHER ANIMAL MODELS, BY REGION, 2018–2025 (USD MILLION)            87
・       TABLE 38         NORTH AMERICA: IN VIVO TOXICOLOGY MARKET FOR OTHER ANIMAL MODELS, BY COUNTRY, 2018–2025 (USD MILLION)              87
・       TABLE 39         EUROPE: IN VIVO TOXICOLOGY MARKET FOR OTHER ANIMAL MODELS,
BY COUNTRY, 2018–2025 (USD MILLION)            88
・       TABLE 40         ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET FOR OTHER ANIMAL MODELS, BY COUNTRY, 2018–2025 (USD MILLION)       88
・       TABLE 41         LATIN AMERICA: IN VIVO TOXICOLOGY MARKET FOR OTHER ANIMAL MODELS, BY COUNTRY, 2018–2025 (USD MILLION)       88
6.3         INSTRUMENTS 89
6.3.1      GROWING RESEARCH AND INTRODUCTION OF COMBINATION INSTRUMENTS ARE KEY GROWTH FACTORS     89
・       TABLE 42         IN VIVO TOXICOLOGY MARKET FOR INSTRUMENTS, BY REGION,
2018–2025 (USD MILLION)          89
・       TABLE 43         NORTH AMERICA: IN VIVO TOXICOLOGY MARKET FOR INSTRUMENTS,
BY COUNTRY, 2018–2025 (USD MILLION)            90
・       TABLE 44         EUROPE: IN VIVO TOXICOLOGY MARKET FOR INSTRUMENTS, BY COUNTRY, 2018–2025 (USD MILLION)           90

・       TABLE 45         ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET FOR INSTRUMENTS,
 BY COUNTRY, 2018–2025 (USD MILLION)          90
・       TABLE 46         LATIN AMERICA: IN VIVO TOXICOLOGY MARKET FOR INSTRUMENTS,
BY COUNTRY, 2018–2025 (USD MILLION)            91

7            IN VIVO TOXICOLOGY MARKET, BY TEST TYPE 92

7.1         INTRODUCTION            93
・       TABLE 47         IN VIVO TOXICOLOGY MARKET, BY TEST TYPE, 2018–2025 (USD MILLION)     93
7.2         CHRONIC TOXICITY TESTING  93
7.2.1      CHRONIC TOXICITY TESTING IS ESSENTIAL FOR NEW DRUG ENTITY APPROVALS      93
・       TABLE 48         CHRONIC TOXICITY TESTING MARKET, BY REGION,
2018–2025 (USD MILLION)          94
・       TABLE 49         NORTH AMERICA: CHRONIC TOXICITY TESTING MARKET, BY COUNTRY,
2018–2025 (USD MILLION)          94
・       TABLE 50         EUROPE: CHRONIC TOXICITY TESTING MARKET, BY COUNTRY,
2018–2025 (USD MILLION)        94
・       TABLE 51         ASIA PACIFIC: CHRONIC TOXICITY TESTING MARKET, BY COUNTRY,
2018–2025 (USD MILLION)          95
・       TABLE 52         LATIN AMERICA: CHRONIC TOXICITY TESTING MARKET, BY COUNTRY,
2018–2025 (USD MILLION)          95
7.3         SUB-CHRONIC TOXICITY TESTING        95
7.3.1      SUB-CHRONIC TOXICITY TESTS PROVIDE DATA ON MANY PARAMETERS OF CHRONIC TOXICITY  95
・       TABLE 53         SUB-CHRONIC TOXICITY TESTING MARKET, BY REGION, 2018–2025 (USD MILLION)       96
・       TABLE 54         NORTH AMERICA: SUB-CHRONIC TOXICITY TESTING MARKET, BY COUNTRY, 2018–2025 (USD MILLION)         96
・       TABLE 55         EUROPE: SUB-CHRONIC TOXICITY TESTING MARKET, BY COUNTRY, 2018–2025 (USD MILLION)            96
・       TABLE 56         ASIA PACIFIC: SUB-CHRONIC TOXICITY TESTING MARKET, BY COUNTRY, 2018–2025 (USD MILLION)         97
・       TABLE 57         LATIN AMERICA: SUB-CHRONIC TOXICITY TESTING MARKET, BY COUNTRY, 2018–2025 (USD MILLION)         97
7.4         SUB-ACUTE TOXICITY TESTING             97
7.4.1      LONG OBSERVATION REQUIREMENTS AND HIGH ANIMAL SAMPLE SIZES ARE CHALLENGES ASSOCIATED WITH SUB-ACUTE TESTING        97
・       TABLE 58         SUB-ACUTE TOXICITY TESTING MARKET, BY REGION, 2018–2025 (USD MILLION)          98
・       TABLE 59         NORTH AMERICA: SUB-ACUTE TOXICITY TESTING MARKET, BY COUNTRY, 2018–2025 (USD MILLION)         98
・       TABLE 60         EUROPE: SUB-ACUTE TOXICITY TESTING MARKET, BY COUNTRY,
2018–2025 (USD MILLION)          98
・       TABLE 61         ASIA PACIFIC: SUB-ACUTE TOXICITY TESTING MARKET, BY COUNTRY,
2018–2025 (USD MILLION)          99
・       TABLE 62         LATIN AMERICA: SUB-ACUTE TOXICITY TESTING MARKET, BY COUNTRY, 2018–2025 (USD MILLION)         99
7.5         ACUTE TOXICITY TESTING       99
7.5.1      DISADVANTAGES OF ACUTE TOXICITY TESTING HAVE DRIVEN USE OF ALTERNATIVES        99
・       TABLE 63         ALTERNATIVE METHODS TO DETERMINE LD50 IN ACUTE TOXICITY TESTING       100
・       TABLE 64         ACUTE TOXICITY TESTING MARKET, BY REGION, 2018–2025 (USD MILLION)          100
・       TABLE 65         NORTH AMERICA: ACUTE TOXICITY TESTING MARKET, BY COUNTRY, 2018–2025 (USD MILLION)         100
・       TABLE 66         EUROPE: ACUTE TOXICITY TESTING MARKET, BY COUNTRY,
2018–2025 (USD MILLION)          101
・       TABLE 67         ASIA PACIFIC: ACUTE TOXICITY TESTING MARKET, BY COUNTRY,
2018–2025 (USD MILLION)          101
・       TABLE 68         LATIN AMERICA: ACUTE TOXICITY TESTING MARKET, BY COUNTRY,
2018–2025 (USD MILLION)          101

8            IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY 102

8.1         INTRODUCTION            103
・       TABLE 69        IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2018–2025 (USD MILLION)          103
8.2         OUTSOURCED TESTING FACILITIES     103
8.2.1      FOCUS ON COST CURTAILMENT AND NEED TO ACCESS SKILLED LABOR & EXPERTISE HAS BOOSTED OUTSOURCING     103
・       TABLE 70         IN VIVO TOXICOLOGY MARKET FOR OUTSOURCED TESTING FACILITIES,
BY REGION, 2018–2025 (USD MILLION)  104
・       TABLE 71         NORTH AMERICA: IN VIVO TOXICOLOGY MARKET FOR OUTSOURCED TESTING FACILITIES, BY COUNTRY, 2018–2025 (USD MILLION)          105
・       TABLE 72         EUROPE: IN VIVO TOXICOLOGY MARKET FOR OUTSOURCED TESTING FACILITIES, BY COUNTRY, 2018–2025 (USD MILLION)              105
・       TABLE 73         ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET FOR OUTSOURCED TESTING FACILITIES, BY COUNTRY, 2018–2025 (USD MILLION)              105
・       TABLE 74         LATIN AMERICA: IN VIVO TOXICOLOGY MARKET FOR OUTSOURCED TESTING FACILITIES, BY COUNTRY, 2018–2025 (USD MILLION)              106
8.3         IN-HOUSE TESTING FACILITIES             106
8.3.1      HIGH COSTS OF IN-HOUSE TESTING RESTRICT MARKET GROWTH              106
・       TABLE 75         IN VIVO TOXICOLOGY MARKET FOR IN-HOUSE TESTING FACILITIES, BY REGION, 2018–2025 (USD MILLION)     106
・       TABLE 76         NORTH AMERICA: IN VIVO TOXICOLOGY MARKET FOR IN-HOUSE TESTING FACILITIES, BY COUNTRY, 2018–2025 (USD MILLION)              107
・       TABLE 77         EUROPE: IN VIVO TOXICOLOGY MARKET FOR IN-HOUSE TESTING FACILITIES, BY COUNTRY, 2018–2025 (USD MILLION) 107
・       TABLE 78         ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET FOR IN-HOUSE TESTING FACILITIES, BY COUNTRY, 2018–2025 (USD MILLION) 107
・       TABLE 79         LATIN AMERICA: IN VIVO TOXICOLOGY MARKET FOR IN-HOUSE TESTING FACILITIES, BY COUNTRY, 2018–2025 (USD MILLION)              108

9            IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT         109

9.1         INTRODUCTION            110
・       TABLE 80         IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2018–2025 (USD MILLION)          110
9.2         IMMUNOTOXICITY       110
9.2.1      IMMUNOTOXICITY TESTING HOLDS THE LARGEST SHARE OF THE MARKET,
BY ENDPOINT 110
・       TABLE 81         IN VIVO TOXICOLOGY MARKET FOR IMMUNOTOXICITY, BY REGION,
2018–2025 (USD MILLION)          111
・       TABLE 82         NORTH AMERICA: IN VIVO TOXICOLOGY MARKET FOR IMMUNOTOXICITY,
BY COUNTRY, 2018–2025 (USD MILLION)            111
・       TABLE 83         EUROPE: IN VIVO TOXICOLOGY MARKET FOR IMMUNOTOXICITY, BY COUNTRY, 2018–2025 (USD MILLION)    111
・       TABLE 84         ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET FOR IMMUNOTOXICITY,
BY COUNTRY, 2018–2025 (USD MILLION)            112
・       TABLE 85         LATIN AMERICA: IN VIVO TOXICOLOGY MARKET FOR IMMUNOTOXICITY,
BY COUNTRY, 2018–2025 (USD MILLION)            112
9.3         SYSTEMIC TOXICITY     112
9.3.1      SYSTEMIC TOXICITY HELPS IDENTIFY A RANGE OF PARAMETERS IN PHARMA/BIOLOGIC TESTING  112
・       TABLE 86         IN VIVO TOXICOLOGY MARKET FOR SYSTEMIC TOXICITY, BY REGION,
2018–2025 (USD MILLION)          113
・       TABLE 87         NORTH AMERICA: IN VIVO TOXICOLOGY MARKET FOR SYSTEMIC TOXICITY,
BY COUNTRY, 2018–2025 (USD MILLION)            113
・       TABLE 88         EUROPE: IN VIVO TOXICOLOGY MARKET FOR SYSTEMIC TOXICITY,
BY COUNTRY, 2018–2025 (USD MILLION)          113
・       TABLE 89         ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET FOR SYSTEMIC TOXICITY,
BY COUNTRY, 2018–2025 (USD MILLION)            114
・       TABLE 90         LATIN AMERICA: IN VIVO TOXICOLOGY MARKET FOR SYSTEMIC TOXICITY,
BY COUNTRY, 2018–2025 (USD MILLION)            114
9.4         CARCINOGENICITY       114
9.4.1      RISING CANCER RESEARCH IS DRIVING THE MARKET FOR CARCINOGENICITY TESTING   114
・       TABLE 91         IN VIVO TOXICOLOGY MARKET FOR CARCINOGENICITY, BY REGION,
2018–2025 (USD MILLION)          115
・       TABLE 92         NORTH AMERICA: IN VIVO TOXICOLOGY MARKET FOR CARCINOGENICITY,
BY COUNTRY, 2018–2025 (USD MILLION)            115
・       TABLE 93         EUROPE: IN VIVO TOXICOLOGY MARKET FOR CARCINOGENICITY,
BY COUNTRY, 2018–2025 (USD MILLION)            115
・       TABLE 94         ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET FOR CARCINOGENICITY,
BY COUNTRY, 2018–2025 (USD MILLION)            116
・       TABLE 95         LATIN AMERICA: IN VIVO TOXICOLOGY MARKET FOR CARCINOGENICITY,
BY COUNTRY, 2018–2025 (USD MILLION)            116
9.5         GENOTOXICITY             116
9.5.1      GENOTOXICITY TESTING HELPS ISOLATE MUTATIVE SUBSTANCES              116
・       TABLE 96         TYPES OF GENOTOXICITY TESTS          117
・       TABLE 97         IN VIVO TOXICOLOGY MARKET FOR GENOTOXICITY, BY REGION,
2018–2025 (USD MILLION)          117
・       TABLE 98         NORTH AMERICA: IN VIVO TOXICOLOGY MARKET FOR GENOTOXICITY,
BY COUNTRY, 2018–2025 (USD MILLION)            118
・       TABLE 99         EUROPE: IN VIVO TOXICOLOGY MARKET FOR GENOTOXICITY, BY COUNTRY, 2018–2025 (USD MILLION)         118
・       TABLE 100       ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET FOR GENOTOXICITY,
BY COUNTRY, 2018–2025 (USD MILLION)            118
・       TABLE 101       LATIN AMERICA: IN VIVO TOXICOLOGY MARKET FOR GENOTOXICITY,
BY COUNTRY, 2018–2025 (USD MILLION)            119
9.6         DEVELOPMENTAL & REPRODUCTIVE TOXICITY            119
9.6.1      RISING PREVALENCE OF SEXUAL HEALTH & DEVELOPMENTAL ABNORMALITIES DRIVE MARKET GROWTH      119
・       TABLE 102       IN VIVO TOXICOLOGY MARKET FOR DART, BY REGION,
2018–2025 (USD MILLION)          119
・       TABLE 103       NORTH AMERICA: IN VIVO TOXICOLOGY MARKET FOR DART, BY COUNTRY, 2018–2025 (USD MILLION)     120
・       TABLE 104       EUROPE: IN VIVO TOXICOLOGY MARKET FOR DART, BY COUNTRY,
2018–2025 (USD MILLION)          120
・       TABLE 105       ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET FOR DART, BY COUNTRY,
2018–2025 (USD MILLION)          120
・       TABLE 106       LATIN AMERICA: IN VIVO TOXICOLOGY MARKET FOR DART, BY COUNTRY, 2018–2025 (USD MILLION) 121
9.7         OTHER TOXICITY ENDPOINTS 121
・       TABLE 107       IN VIVO TOXICOLOGY MARKET FOR OTHER TOXICITY ENDPOINTS, BY REGION, 2018–2025 (USD MILLION)      121
・       TABLE 108       NORTH AMERICA: IN VIVO TOXICOLOGY MARKET FOR OTHER TOXICITY ENDPOINTS, BY COUNTRY, 2018–2025 (USD MILLION)              122
・       TABLE 109       EUROPE: IN VIVO TOXICOLOGY MARKET FOR OTHER TOXICITY ENDPOINTS,
BY COUNTRY, 2018–2025 (USD MILLION)            122
・       TABLE 110       ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET FOR OTHER TOXICITY ENDPOINTS, BY COUNTRY, 2018–2025 (USD MILLION)              122
・       TABLE 111       LATIN AMERICA: IN VIVO TOXICOLOGY MARKET FOR OTHER TOXICITY ENDPOINTS, BY COUNTRY, 2018–2025 (USD MILLION)              123

10          IN VIVO TOXICOLOGY MARKET, BY END USER 124

10.1       INTRODUCTION            125
・       TABLE 112       IN VIVO TOXICOLOGY MARKET, BY END USER, 2018–2025 (USD MILLION)     125
10.2       ACADEMIC & RESEARCH INSTITUTES   125
10.2.1    GROWING PARTNERSHIPS AND HIGH USE OF INSTRUMENTS & CONSUMABLES DRIVE MARKET GROWTH         125
・       TABLE 113       IN VIVO TOXICOLOGY MARKET FOR ACADEMIC & RESEARCH INSTITUTES,
BY REGION, 2018–2025 (USD MILLION)  126
・       TABLE 114       NORTH AMERICA: IN VIVO TOXICOLOGY MARKET FOR ACADEMIC & RESEARCH INSTITUTES, BY COUNTRY, 2018–2025 (USD MILLION)          126
・       TABLE 115       EUROPE: IN VIVO TOXICOLOGY MARKET FOR ACADEMIC & RESEARCH INSTITUTES, BY COUNTRY, 2018–2025 (USD MILLION)              126
・       TABLE 116       ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET FOR ACADEMIC & RESEARCH INSTITUTES, BY COUNTRY, 2018–2025 (USD MILLION)              127
・       TABLE 117       LATIN AMERICA: IN VIVO TOXICOLOGY MARKET FOR ACADEMIC & RESEARCH INSTITUTES, BY COUNTRY, 2018–2025 (USD MILLION)              127
10.3       PHARMACEUTICAL & BIOTECHNOLOGY COMPANIES   127
10.3.1    GROWING IMPORTANCE OF PRECLINICAL TOXICOLOGY EVALUATION HAS INCREASED DEMAND FOR TESTING, ESPECIALLY IN PHARMA COMPANIES   127
・       TABLE 118       IN VIVO TOXICOLOGY MARKET FOR PHARMACEUTICAL & BIOTECHNOLOGY COMPANIES, BY REGION, 2018–2025 (USD MILLION) 128
・       TABLE 119       NORTH AMERICA: IN VIVO TOXICOLOGY MARKET FOR PHARMACEUTICAL & BIOTECHNOLOGY COMPANIES, BY COUNTRY, 2018–2025 (USD MILLION)          128
・       TABLE 120       EUROPE: IN VIVO TOXICOLOGY MARKET FOR PHARMACEUTICAL & BIOTECHNOLOGY COMPANIES, BY COUNTRY, 2018–2025 (USD MILLION) 129
・       TABLE 121       ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET FOR PHARMACEUTICAL & BIOTECHNOLOGY COMPANIES, BY COUNTRY, 2018–2025 (USD MILLION) 129
・       TABLE 122       LATIN AMERICA: IN VIVO TOXICOLOGY MARKET FOR PHARMACEUTICAL & BIOTECHNOLOGY COMPANIES, BY COUNTRY, 2018–2025 (USD MILLION) 129
10.4       CONTRACT RESEARCH ORGANIZATIONS          130
10.4.1    CONTRACT SERVICES HAVE REGISTERED RISING DEMAND DUE TO INCREASING COSTS OF RESEARCH        130
・       TABLE 123       IN VIVO TOXICOLOGY MARKET FOR CONTRACT RESEARCH ORGANIZATIONS, BY REGION, 2018–2025 (USD MILLION)     130
・       TABLE 124       NORTH AMERICA: IN VIVO TOXICOLOGY MARKET FOR CONTRACT RESEARCH ORGANIZATIONS, BY COUNTRY, 2018–2025 (USD MILLION)          130
・       TABLE 125       EUROPE: IN VIVO TOXICOLOGY MARKET FOR CONTRACT RESEARCH ORGANIZATIONS, BY COUNTRY, 2018–2025 (USD MILLION)          131
・       TABLE 126       ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET FOR CONTRACT RESEARCH ORGANIZATIONS, BY COUNTRY, 2018–2025 (USD MILLION)          131
・       TABLE 127       LATIN AMERICA: IN VIVO TOXICOLOGY MARKET FOR CONTRACT RESEARCH ORGANIZATIONS, BY COUNTRY, 2018–2025 (USD MILLION)          131
10.5       OTHER END USERS        132
・       TABLE 128       IN VIVO TOXICOLOGY MARKET FOR OTHER END USERS, BY REGION,
2018–2025 (USD MILLION)          132
・       TABLE 129       NORTH AMERICA: IN VIVO TOXICOLOGY MARKET FOR OTHER END USERS,
BY COUNTRY, 2018–2025 (USD MILLION)            133
・       TABLE 130       EUROPE: IN VIVO TOXICOLOGY MARKET FOR OTHER END USERS,
BY COUNTRY, 2018–2025 (USD MILLION)          133
・       TABLE 131       ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET FOR OTHER END USERS,
BY COUNTRY, 2018–2025 (USD MILLION)            133
・       TABLE 132       LATIN AMERICA: IN VIVO TOXICOLOGY MARKET FOR OTHER END USERS,
BY COUNTRY, 2018–2025 (USD MILLION)          134

11          IN VIVO TOXICOLOGY MARKET, BY REGION     135

11.1       INTRODUCTION            136
・       FIGURE 20        IN VIVO TOXICOLOGY MARKET SNAPSHOT      136
・       TABLE 133       IN VIVO TOXICOLOGY MARKET, BY REGION, 2018–2025 (USD MILLION) 136
11.2       NORTH AMERICA          137
・       FIGURE 21        NORTH AMERICA: IN VIVO TOXICOLOGY MARKET SNAPSHOT        137
・       TABLE 134       NORTH AMERICA: IN VIVO TOXICOLOGY MARKET, BY COUNTRY,
2018–2025 (USD MILLION)          138
・       TABLE 135       NORTH AMERICA: IN VIVO TOXICOLOGY MARKET, BY PRODUCT,
2018–2025 (USD MILLION)          138
・       TABLE 136       NORTH AMERICA: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES,
BY TYPE, 2018–2025 (USD MILLION)       138
・       TABLE 137       NORTH AMERICA: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS,
BY TYPE, 2018–2025 (USD MILLION)       139
・       TABLE 138       NORTH AMERICA: IN VIVO TOXICOLOGY MARKET, BY TEST TYPE,
2018–2025 (USD MILLION)          139
・       TABLE 139       NORTH AMERICA: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT, 2018–2025 (USD MILLION)           139
・       TABLE 140       NORTH AMERICA: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY, 2018–2025 (USD MILLION)  140
・       TABLE 141       NORTH AMERICA: IN VIVO TOXICOLOGY MARKET, BY END USER,
2018–2025 (USD MILLION)          140
11.2.1    US         140
11.2.1.1 GOVERNMENT FUNDING FOR LIFE SCIENCES RESEARCH DRIVES THE MARKET GROWTH IN THE US   140
・       TABLE 142       US: IN VIVO TOXICOLOGY MARKET, BY PRODUCT, 2018–2025 (USD MILLION)          141
・       TABLE 143       US: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES, BY TYPE,
2018–2025 (USD MILLION)          141
・       TABLE 144       US: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE,
2018–2025 (USD MILLION)          142
・       TABLE 145       US: IN VIVO TOXICOLOGY MARKET, BY TEST TYPE, 2018–2025 (USD MILLION)          142
・       TABLE 146       US: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2018–2025 (USD MILLION)          142
・       TABLE 147       US: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2018–2025 (USD MILLION)          143
・       TABLE 148       US: IN VIVO TOXICOLOGY MARKET, BY END USER,
2018–2025 (USD MILLION)          143
11.2.2    CANADA            143
11.2.2.1 GROWTH IN STEM CELL RESEARCH ACTIVITIES EXPECTED TO LEAD TO MARKET EXPANSION           143
・       TABLE 149       CANADA: IN VIVO TOXICOLOGY MARKET, BY PRODUCT,
2018–2025 (USD MILLION)          144
・       TABLE 150       CANADA: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES, BY TYPE, 2018–2025 (USD MILLION)     144
・       TABLE 151       CANADA: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE, 2018–2025 (USD MILLION)  144
・       TABLE 152       CANADA: IN VIVO TOXICOLOGY MARKET, BY TEST TYPE,
2018–2025 (USD MILLION)          145
・       TABLE 153       CANADA: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2018–2025 (USD MILLION)          145
・       TABLE 154       CANADA: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2018–2025 (USD MILLION)          145
・       TABLE 155       CANADA: IN VIVO TOXICOLOGY MARKET, BY END USER,
2018–2025 (USD MILLION)          146
11.3       EUROPE             146
・       TABLE 156       EUROPE: IN VIVO TOXICOLOGY MARKET, BY COUNTRY,
2018–2025 (USD MILLION)          146
・       TABLE 157       EUROPE: IN VIVO TOXICOLOGY MARKET, BY PRODUCT,
2018–2025 (USD MILLION)          147
・       TABLE 158       EUROPE: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES, BY TYPE, 2018–2025 (USD MILLION)     147
・       TABLE 159       EUROPE: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE, 2018–2025 (USD MILLION)   147
・       TABLE 160       EUROPE: IN VIVO TOXICOLOGY MARKET, BY TEST TYPE,
2018–2025 (USD MILLION)          148
・       TABLE 161       EUROPE: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2018–2025 (USD MILLION)          148
・       TABLE 162       EUROPE: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2018–2025 (USD MILLION)          148
・       TABLE 163       EUROPE: IN VIVO TOXICOLOGY MARKET, BY END USER,
2018–2025 (USD MILLION)          149
11.3.1    UK         149
11.3.1.1 INCREASING FOCUS ON CANCER RESEARCH IN THE UK IS A KEY MARKET GROWTH DRIVER       149
・       TABLE 164       UK: IN VIVO TOXICOLOGY MARKET, BY PRODUCT, 2018–2025 (USD MILLION)          149
・       TABLE 165       UK: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES, BY TYPE,
2018–2025 (USD MILLION)          150
・       TABLE 166       UK: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE,
2018–2025 (USD MILLION)          150
・       TABLE 167       UK: IN VIVO TOXICOLOGY MARKET, BY TEST TYPE, 2018–2025 (USD MILLION)          150
・       TABLE 168       UK: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2018–2025 (USD MILLION)          151
・       TABLE 169       UK: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2018–2025 (USD MILLION)          151
・       TABLE 170       UK: IN VIVO TOXICOLOGY MARKET, BY END USER,
2018–2025 (USD MILLION)          151
11.3.2    GERMANY         152
11.3.2.1 GERMANY ACCOUNTED FOR THE SECOND-LARGEST SHARE OF THE EUROPEAN MARKET     152
・       TABLE 171       GERMANY: IN VIVO TOXICOLOGY MARKET, BY PRODUCT,
2018–2025 (USD MILLION)          152
・       TABLE 172       GERMANY: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES, BY TYPE, 2018–2025 (USD MILLION)     152
・       TABLE 173       GERMANY: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE, 2018–2025 (USD MILLION)  153
・       TABLE 174       GERMANY: IN VIVO TOXICOLOGY MARKET, BY TEST TYPE,
2018–2025 (USD MILLION)          153
・       TABLE 175       GERMANY: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2018–2025 (USD MILLION)          153
・       TABLE 176       GERMANY: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2018–2025 (USD MILLION)          154
・       TABLE 177       GERMANY: IN VIVO TOXICOLOGY MARKET, BY END USER,
2018–2025 (USD MILLION)          154
11.3.3    FRANCE             154
11.3.3.1 INCREASED INVESTMENTS IN PROTEOMICS AND GENOMICS TO FUEL GROWTH OF MICE MODELS     154
・       TABLE 178       FRANCE: IN VIVO TOXICOLOGY MARKET, BY PRODUCT,
2018–2025 (USD MILLION)          155
・       TABLE 179       FRANCE: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES, BY TYPE, 2018–2025 (USD MILLION)     155
・       TABLE 180       FRANCE: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE, 2018–2025 (USD MILLION)   155
・       TABLE 181       FRANCE: IN VIVO TOXICOLOGY MARKET, BY TEST TYPE,
2018–2025 (USD MILLION)          156
・       TABLE 182       FRANCE: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2018–2025 (USD MILLION)          156
・       TABLE 183       FRANCE: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2018–2025 (USD MILLION)          156
・       TABLE 184       FRANCE: IN VIVO TOXICOLOGY MARKET, BY END USER,
2018–2025 (USD MILLION)          157
11.3.4    ITALY   157
11.3.4.1 GROWTH IN THE BIOTECHNOLOGY AND PHARMACEUTICAL INDUSTRIES TO DRIVE MARKET GROWTH        157
・       TABLE 185       ITALY: IN VIVO TOXICOLOGY MARKET, BY PRODUCT,
2018–2025 (USD MILLION)          157
・       TABLE 186       ITALY: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES, BY TYPE,
2018–2025 (USD MILLION)          158
・       TABLE 187       ITALY: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE,
2018–2025 (USD MILLION)          158
・       TABLE 188       ITALY: IN VIVO TOXICOLOGY MARKET, BY TEST TYPE,
2018–2025 (USD MILLION)          158
・       TABLE 189       ITALY: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2018–2025 (USD MILLION)          159
・       TABLE 190       ITALY: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2018–2025 (USD MILLION)          159
・       TABLE 191       ITALY: IN VIVO TOXICOLOGY MARKET, BY END USER,
2018–2025 (USD MILLION)          159
11.3.5    SPAIN   160
11.3.5.1 SHORT STUDY START-UP TIMES AND RISING R&D EXPENDITURE TO BOOST THE GROWTH OF THE SPANISH MARKET          160
・       TABLE 192       SPAIN: IN VIVO TOXICOLOGY MARKET, BY PRODUCT,
2018–2025 (USD MILLION)          160
・       TABLE 193       SPAIN: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES, BY TYPE,
2018–2025 (USD MILLION)          160
・       TABLE 194       SPAIN: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE,
2018–2025 (USD MILLION)          161
・       TABLE 195       SPAIN: IN VIVO TOXICOLOGY MARKET, BY TEST TYPE,
2018–2025 (USD MILLION)          161
・       TABLE 196       SPAIN: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2018–2025 (USD MILLION)          161
・       TABLE 197       SPAIN: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2018–2025 (USD MILLION)        162
・       TABLE 198       SPAIN: IN VIVO TOXICOLOGY MARKET, BY END USER,
2018–2025 (USD MILLION)          162
11.3.6    REST OF EUROPE           162
・       TABLE 199       ROE: IN VIVO TOXICOLOGY MARKET, BY PRODUCT,
2018–2025 (USD MILLION)          163
・       TABLE 200       ROE: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES,
BY TYPE, 2018–2025 (USD MILLION)       163
・       TABLE 201       ROE: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS,
BY TYPE, 2018–2025 (USD MILLION)       163
・       TABLE 202       ROE: IN VIVO TOXICOLOGY MARKET, BY TEST TYPE,
2018–2025 (USD MILLION)          164
・       TABLE 203       ROE: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2018–2025 (USD MILLION)          164
・       TABLE 204       ROE: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2018–2025 (USD MILLION)          164
・       TABLE 205       ROE: IN VIVO TOXICOLOGY MARKET, BY END USER,
2018–2025 (USD MILLION)          165
11.4       ASIA PACIFIC    165
・       FIGURE 22        ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET SNAPSHOT        166
・       TABLE 206       ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET, BY COUNTRY,
2018–2025 (USD MILLION)        167
・       TABLE 207       ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET, BY PRODUCT,
2018–2025 (USD MILLION)          167
・       TABLE 208       ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES, BY TYPE, 2018–2025 (USD MILLION)     167
・       TABLE 209       ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE, 2018–2025 (USD MILLION)  168
・       TABLE 210       ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET, BY TEST TYPE,
2018–2025 (USD MILLION)          168

・       TABLE 211       ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2018–2025 (USD MILLION)          168
・       TABLE 212       ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2018–2025 (USD MILLION)          169
・       TABLE 213       ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET, BY END USER,
2018–2025 (USD MILLION)          169
11.4.1    CHINA  169
11.4.1.1 INTERNATIONAL ALLIANCES FOR R&D ARE DRIVING THE MARKET              169
・       TABLE 214       CHINA: IN VIVO TOXICOLOGY MARKET, BY PRODUCT,
2018–2025 (USD MILLION)          170
・       TABLE 215       CHINA: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES, BY TYPE,
2018–2025 (USD MILLION)          170
・       TABLE 216       CHINA: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE,
2018–2025 (USD MILLION)          170
・       TABLE 217      CHINA: IN VIVO TOXICOLOGY MARKET, BY TEST TYPE,
2018–2025 (USD MILLION)          171
・       TABLE 218       CHINA: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2018–2025 (USD MILLION)          171
・       TABLE 219       CHINA: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2018–2025 (USD MILLION)          171
・       TABLE 220       CHINA: IN VIVO TOXICOLOGY MARKET, BY END USER,
2018–2025 (USD MILLION)          172
11.4.2    JAPAN  172
11.4.2.1 INCREASING FOCUS ON PERSONALIZED DIAGNOSTICS PRODUCTS TO SUPPORT MARKET GROWTH    172
・       TABLE 221       JAPAN: IN VIVO TOXICOLOGY MARKET, BY PRODUCT,
 2018–2025 (USD MILLION)        172
・       TABLE 222       JAPAN: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES, BY TYPE,
2018–2025 (USD MILLION)          173
・       TABLE 223       JAPAN: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE,
2018–2025 (USD MILLION)          173
・       TABLE 224       JAPAN: IN VIVO TOXICOLOGY MARKET, BY TEST TYPE,
2018–2025 (USD MILLION)          173
・       TABLE 225       JAPAN: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2018–2025 (USD MILLION)          174
・       TABLE 226       JAPAN: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2018–2025 (USD MILLION)          174
・       TABLE 227       JAPAN: IN VIVO TOXICOLOGY MARKET, BY END USER,
2018–2025 (USD MILLION)          174
11.4.3    INDIA   175
11.4.3.1 ROBUST GROWTH IN THE BIOTECH INDUSTRY IN INDIA TO BOOST THE MARKET GROWTH             175
・       TABLE 228       INDIA: IN VIVO TOXICOLOGY MARKET, BY PRODUCT,
2018–2025 (USD MILLION)          175
・       TABLE 229       INDIA: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES, BY TYPE,
2018–2025 (USD MILLION)          175
・       TABLE 230       INDIA: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE,
2018–2025 (USD MILLION)          176
・       TABLE 231       INDIA: IN VIVO TOXICOLOGY MARKET, BY TEST TYPE,
2018–2025 (USD MILLION)          176
・       TABLE 232       INDIA: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2018–2025 (USD MILLION)          176
・       TABLE 233       INDIA: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2018–2025 (USD MILLION)          177
・       TABLE 234       INDIA: IN VIVO TOXICOLOGY MARKET, BY END USER,
2018–2025 (USD MILLION)          177
11.4.4    REST OF ASIA PACIFIC  177
・       TABLE 235       ROAPAC: IN VIVO TOXICOLOGY MARKET, BY PRODUCT,
2018–2025 (USD MILLION)          178
・       TABLE 236       ROAPAC: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES, BY TYPE, 2018–2025 (USD MILLION)     178
・       TABLE 237       ROAPAC: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE, 2018–2025 (USD MILLION)   178
・       TABLE 238       ROAPAC: IN VIVO TOXICOLOGY MARKET, BY TEST TYPE,
2018–2025 (USD MILLION)          179
・       TABLE 239       ROAPAC: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2018–2025 (USD MILLION)          179
・       TABLE 240       ROAPAC: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2018–2025 (USD MILLION)          179
・       TABLE 241       ROAPAC: IN VIVO TOXICOLOGY MARKET, BY END USER,
2018–2025 (USD MILLION)          180
11.5       LATIN AMERICA             180
・       TABLE 242       LATIN AMERICA: IN VIVO TOXICOLOGY MARKET, BY COUNTRY,
2018–2025 (USD MILLION)          180
・       TABLE 243       LATIN AMERICA: IN VIVO TOXICOLOGY MARKET, BY PRODUCT,
2018–2025 (USD MILLION)          181
・       TABLE 244       LATIN AMERICA: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES, BY TYPE, 2018–2025 (USD MILLION)     181
・       TABLE 245       LATIN AMERICA: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS,
BY TYPE, 2018–2025 (USD MILLION)       181
・       TABLE 246       LATIN AMERICA: IN VIVO TOXICOLOGY MARKET, BY TEST TYPE,
2018–2025 (USD MILLION)          182
・       TABLE 247       LATIN AMERICA: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT, 2018–2025 (USD MILLION)           182
・       TABLE 248       LATIN AMERICA: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2018–2025 (USD MILLION)          182
・       TABLE 249       LATIN AMERICA: IN VIVO TOXICOLOGY MARKET, BY END USER,
2018–2025 (USD MILLION)          183
11.5.1    BRAZIL 183
11.5.1.1 GROWING BIOLOGICS SECTOR IN THE COUNTRY TO DRIVE THE MARKET            183
・       TABLE 250      BRAZIL: IN VIVO TOXICOLOGY MARKET, BY PRODUCT,
2018–2025 (USD MILLION)          183
・       TABLE 251       BRAZIL: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES, BY TYPE,
2018–2025 (USD MILLION)          184
・       TABLE 252       BRAZIL: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE, 2018–2025 (USD MILLION)   184
・       TABLE 253       BRAZIL: IN VIVO TOXICOLOGY MARKET, BY TEST TYPE,
2018–2025 (USD MILLION)          184
・       TABLE 254       BRAZIL: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2018–2025 (USD MILLION)          185
・       TABLE 255       BRAZIL: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2018–2025 (USD MILLION)          185
・       TABLE 256      BRAZIL: IN VIVO TOXICOLOGY MARKET, BY END USER,
2018–2025 (USD MILLION)          185
11.5.2    MEXICO             186
11.5.2.1 FAVORABLE BUSINESS ENVIRONMENT FOR MARKET PLAYERS TO SUPPORT MARKET GROWTH    186
・       TABLE 257       MEXICO: IN VIVO TOXICOLOGY MARKET, BY PRODUCT,
2018–2025 (USD MILLION)          186
・       TABLE 258       MEXICO: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES, BY TYPE,
2018–2025 (USD MILLION)          186
・       TABLE 259       MEXICO: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE, 2018–2025 (USD MILLION)   187
・       TABLE 260       MEXICO: IN VIVO TOXICOLOGY MARKET, BY TEST TYPE,
2018–2025 (USD MILLION)          187
・       TABLE 261       MEXICO: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2018–2025 (USD MILLION)          187
・       TABLE 262       MEXICO: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
 2018–2025 (USD MILLION)        188
・       TABLE 263       MEXICO: IN VIVO TOXICOLOGY MARKET, BY END USER,
2018–2025 (USD MILLION)          188
11.5.3    REST OF LATIN AMERICA          188
・       TABLE 264       ROLATAM: IN VIVO TOXICOLOGY MARKET, BY PRODUCT,
2018–2025 (USD MILLION)          188
・       TABLE 265       ROLATAM: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES, BY TYPE, 2018–2025 (USD MILLION)     189
・       TABLE 266       ROLATAM: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE, 2018–2025 (USD MILLION)  189
・       TABLE 267       ROLATAM: IN VIVO TOXICOLOGY MARKET, BY TEST TYPE,
2018–2025 (USD MILLION)          189
・       TABLE 268       ROLATAM: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2018–2025 (USD MILLION)          190
・       TABLE 269       ROLATAM: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2018–2025 (USD MILLION)          190
・       TABLE 270       ROLATAM: IN VIVO TOXICOLOGY MARKET, BY END USER,
2018–2025 (USD MILLION)          190
11.6       MIDDLE EAST & AFRICA             191
11.6.1    INFRASTRUCTURAL DEVELOPMENT TO CONTRIBUTE TO MARKET GROWTH IN THE MEA  191
・       TABLE 271       MIDDLE EAST & AFRICA: IN VIVO TOXICOLOGY MARKET, BY PRODUCT,
2018–2025 (USD MILLION)          191
・       TABLE 272       MIDDLE EAST & AFRICA: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES, BY TYPE, 2018–2025 (USD MILLION)        191
・       TABLE 273       MIDDLE EAST & AFRICA: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE, 2018–2025 (USD MILLION)     192
・       TABLE 274       MIDDLE EAST & AFRICA: IN VIVO TOXICOLOGY MARKET, BY TEST TYPE,
2018–2025 (USD MILLION)          192
・       TABLE 275       MIDDLE EAST & AFRICA: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT, 2018–2025 (USD MILLION)  193
・       TABLE 276       MIDDLE EAST & AFRICA: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY, 2018–2025 (USD MILLION)       193
・       TABLE 277       MIDDLE EAST & AFRICA: IN VIVO TOXICOLOGY MARKET, BY END USER, 2018–2025 (USD MILLION)         193

12          COMPETITIVE LANDSCAPE       194

12.1       INTRODUCTION            194
12.2       MARKET SHARE ANALYSIS (2019)           194
・       FIGURE 23       IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY KEY PLAYER, 2019    194
12.2.1    ENVIGO (US)    195
12.3       MARKET RANKING ANALYSIS   196
・       FIGURE 24        COMPANY RANKING IN THE IN VIVO TOXICOLOGY INSTRUMENTS MARKET, 2019   196
12.4       MARKET EVALUATION FRAMEWORK (ANIMAL MODELS)           197
・       TABLE 278       MARKET EVALUATION FRAMEWORK: PRODUCT LAUNCHES WAS THE MAJOR STRATEGY ADOPTED BY PLAYERS             197
12.5       COMPETITIVE SCENARIO          197
12.5.1    KEY PRODUCT LAUNCHES        197
12.5.2    KEY ACQUISITIONS       198
12.5.3    KEY COLLABORATIONS             198
12.5.4    KEY EXPANSIONS          198
12.6       MARKET EVALUATION FRAMEWORK (INSTRUMENTS) 199
12.6.1    KEY MARKET DEVELOPMENTS 199
12.6.1.1 PRODUCT LAUNCHES  199
12.6.1.2 ACQUISITIONS 199
12.6.1.3 PARTNERSHIPS, COLLABORATIONS, AND AGREEMENTS            200
12.6.1.4 EXPANSIONS    200
12.7       COMPANY PRODUCT FOOTPRINT         201
・       TABLE 279       PRODUCT PORTFOLIO ANALYSIS: IN VIVO TOXICOLOGY MARKET (ANIMAL MODELS)       201
12.8       COMPANY GEOGRAPHIC FOOTPRINT  202
・       TABLE 280       GEOGRAPHIC REVENUE MIX: IN VIVO TOXICOLOGY MARKET (2019) 202
12.9       REVENUE ANALYSIS OF KEY MARKET PLAYERS 203
・       FIGURE 25        REVENUE ANALYSIS: IN VIVO TOXICOLOGY MARKET (2019)   203
12.10     COMPETITIVE LEADERSHIP MAPPING: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS             204
12.10.1  STARS  204
12.10.2  EMERGING LEADERS    204
12.10.3  PERVASIVE PLAYERS     204
12.10.4  PARTICIPANTS 205
・       FIGURE 26        IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS: COMPANY EVALUATION MATRIX, 2019           205
12.11     COMPETITIVE LEADERSHIP MAPPING: IN VIVO TOXICOLOGY MARKET FOR INSTRUMENTS    206
12.11.1  STARS  206
12.11.2  EMERGING LEADERS    206
12.11.3  PERVASIVE PLAYERS     206
12.11.4  PARTICIPANTS 206
・       FIGURE 27        IN VIVO TOXICOLOGY MARKET FOR INSTRUMENTS: COMPANY EVALUATION MATRIX, 2019 207

13          COMPANY PROFILES    208

13.1       MAJOR PLAYERS            208
(BUSINESS OVERVIEW, PRODUCTS OFFERED, RECENT DEVELOPMENTS, MNM VIEW)*
13.1.1    CHARLES RIVER LABORATORIES            208
・       TABLE 281       CHARLES RIVER LABORATORIES: BUSINESS OVERVIEW        208
・       FIGURE 28        CHARLES RIVER LABORATORIES: COMPANY SNAPSHOT (2019)          209
13.1.2    THE JACKSON LABORATORY    212
・       TABLE 282       THE JACKSON LABORATORY: BUSINESS OVERVIEW              212
・       FIGURE 29        THE JACKSON LABORATORY: COMPANY SNAPSHOT (2019)   212
13.1.3    ENVIGO             215
・       TABLE 283       ENVIGO: BUSINESS OVERVIEW 215
13.1.4    TACONIC BIOSCIENCES             218
・       TABLE 284       TACONIC BIOSCIENCES, INC.: BUSINESS OVERVIEW              218
13.1.5    GENOWAY        221
・       TABLE 285       GENOWAY: BUSINESS OVERVIEW          221
・       FIGURE 30        GENOWAY: COMPANY SNAPSHOT (2019)           221
13.1.6    HARBOUR BIOMED       224
・       TABLE 286       HARBOUR BIOMED: BUSINESS OVERVIEW         224
13.1.7    CROWN BIOSCIENCE    225
・       TABLE 287       CROWN BIOSCIENCE, INC.: BUSINESS OVERVIEW              225
13.1.8    TRANSCURE BIOSERVICES         228
・       TABLE 288       TRANSCURE BIOSERVICES: BUSINESS OVERVIEW              228
13.1.9    OZGENE PTY LTD.        229
・       TABLE 289       OZGENE PTY LTD.: BUSINESS OVERVIEW           229
13.1.10  THERMO FISHER SCIENTIFIC    230
・       TABLE 290       THERMO FISHER SCIENTIFIC, INC.: BUSINESS OVERVIEW        230
・       FIGURE 31        THERMO FISHER SCIENTIFIC, INC.: COMPANY SNAPSHOT (2019)          231
13.1.11  DANAHER CORPORATION         236
・       TABLE 291       DANAHER CORPORATION: BUSINESS OVERVIEW              236
・       FIGURE 32        DANAHER CORPORATION: COMPANY SNAPSHOT (2019)   236
13.1.12  AGILENT TECHNOLOGIES         239
・       TABLE 292       AGILENT TECHNOLOGIES: BUSINESS OVERVIEW              239
・       FIGURE 33        AGILENT TECHNOLOGIES, INC.: COMPANY SNAPSHOT (2019)          239
13.1.13  WATERS CORPORATION            243
・       TABLE 293       WATERS CORPORATION: BUSINESS OVERVIEW 243
・       FIGURE 34        WATERS CORPORATION: COMPANY SNAPSHOT (2019)              243
13.1.14  SHIMADZU CORPORATION       246
・       TABLE 294       SHIMADZU CORPORATION: BUSINESS OVERVIEW              246
・       FIGURE 35        SHIMADZU CORPORATION: COMPANY SNAPSHOT (2019)   246
13.1.15  BIO-RAD LABORATORIES          249
・       TABLE 295       BIO-RAD LABORATORIES, INC.: BUSINESS OVERVIEW              249
・       FIGURE 36        BIO-RAD LABORATORIES, INC.: COMPANY SNAPSHOT (2019)   250
13.1.16  BRUKER CORPORATION            251
・       TABLE 296       BRUKER CORPORATION: BUSINESS OVERVIEW 251
・       FIGURE 37        BRUKER CORPORATION: COMPANY SNAPSHOT (2019)              251
13.1.17  PERKINELMER 253
・       TABLE 297       PERKINELMER, INC.: BUSINESS OVERVIEW        253
・       FIGURE 38        PERKINELMER, INC.: COMPANY SNAPSHOT (2019)              253
13.2       OTHER PLAYERS           256
13.2.1    MERCK KGAA   256
・       TABLE 298       MERCK KGAA: BUSINESS OVERVIEW     256
・       FIGURE 39        MERCK KGAA: COMPANY SNAPSHOT (2019)      256
13.2.2    GE HEALTHCARE          258
・       TABLE 299       GE HEALTHCARE: BUSINESS OVERVIEW             258
・       FIGURE 40        GE HEALTHCARE: COMPANY SNAPSHOT (2019)              258
13.2.3    JANVIER LABS   260
・       TABLE 300       JANVIER LABS: BUSINESS OVERVIEW     260
13.2.4    INGENIOUS TARGETING LABORATORY 261
・       TABLE 301       INGENIOUS TARGETING LABORATORY: BUSINESS OVERVIEW        261
13.2.5    POLYGENE       263
・       TABLE 302       POLYGENE: BUSINESS OVERVIEW          263
13.2.6    GVK BIO             264
・       TABLE 303       GVK BIO: BUSINESS OVERVIEW 264
13.2.7    CYAGEN BIOSCIENCES 266
・       TABLE 304       CYAGEN BIOSCIENCES: BUSINESS OVERVIEW   266
13.2.8    DATA SCIENCES INTERNATIONAL         267
・       TABLE 305       DATA SCIENCE INTERNATIONAL: BUSINESS OVERVIEW        267
*BUSINESS OVERVIEW, PRODUCTS OFFERED, RECENT DEVELOPMENTS, MNM VIEW MIGHT NOT BE CAPTURED IN CASE OF UNLISTED COMPANIES.

14          APPENDIX         269



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