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市場調査レポート
In Vivo 毒性試験の世界市場：製品別、毒性エンドポイント別2025年予測
In Vivo Toxicology Market by Product (Animal Models, Reagents & Kits), Test Type (Chronic, Sub-acute), Toxicity Endpoints (Systemic, Immunotoxicity), Testing Facility (Outsourced, In-house), End User (Academic & Research Institute, CROs) - Forecast to 2025
- 出版元：MarketsandMarkets
出版元について - 発行年：2021年3月
- 定価 Single User License(1名様ライセンス)US$5,650(米国ドル)/Multi User License(5名様)$6,650 /Corporate User License $8,150
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- 納品形態：PDF by Email
- 当調査レポートは英文264ページになります。
- 商品コード：MAM2387
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【レポート紹介】
In Vivo毒性試験の世界市場規模は、2020年で50億ドル、2025年には66億ドルへと漸増する見通しです。レポートはIn vivo毒性試験の世界市場について2025年までの市場予測データ(金額US$)を掲載しています。また市場をさまざまな切り口で細分化し、そのセグメント市場ごとの市場予測を中心に構成されています。当レポートでの各種セグメント市場の区分は、製品別市場、試験タイプ別市場、試験施設別市場、毒性エンドポイント別市場、エンドユーザー別市場および主要国地域別市場、などとなっています。また競合状況、主要企業情報（17社）、COVID-19によるIn vivo毒性試験市場への影響、特許分析などの分析情報も加味し、In vivo毒性試験市場の今後成長性および動向を詳細にレポートしています。
【レポート構成概要】 
◆In vivo毒性試験の世界市場予測2018-2025年
・市場規模(US$)
◆製品別、市場-2025年
消耗品
・試薬/キット
・動物モデル
-マウスモデル
-ラットモデル
-その他動物モデル
器具
※(市場規模US$)
◆試験タイプ別、市場-2025年
・慢性毒性試験
・亜慢性毒性試験
・亜急性毒性試験
・急性毒性試験
※(市場規模US$)
◆試験施設別、市場-2025年
・外部委託試験施設
・社内試験施設
※(市場規模US$)
◆毒性エンドポイント別、市場-2025年
・免疫毒性
・全身毒性
・発がん性
・遺伝子毒性
・生殖発生毒性
・その他
※(市場規模US$)
◆エンドユーザー別、市場-2025年
・学術研究機関
・製薬/バイオテクノロジー企業
・受託研究機関（CRO）
・その他
※(市場規模US$)
◆主要国地域別市場-2025年
北米
・米国、カナダ
欧州
・英国、フランス、ドイツ、イタリア、スペイン
・その他欧州
アジア太平洋
・日本、中国、インド
・その他アジア太平洋
中南米
・ブラジル、メキシコ
・その他中南米
中東アフリカ
※国地域別に全セグメント別の細分化データ掲載、詳細は目次参照
◆市場分析
・市場ダイナミクス（ドライバー、障壁、機会、課題）
・COVID-19によるIn vivo毒性試験市場への影響
・特許分析
・ファイブフォース分析
・サプライチェーン分析
・バリューチェーン分析
・市場シェア分析-2019年
・競合状況
◆In vivo毒性試験の主要企業プロフィール動向
・CHARLES RIVER LABORATORIES
・THE JACKSON LABORATORY
・ENVIGO
・TACONIC BIOSCIENCES
・GENOWAY
・HARBOUR BIOMED
・CROWN BIOSCIENCE
・TRANSCURE BIOSERVICES
・OZGENE PTY LTD.
・THERMO FISHER SCIENTIFIC
・DANAHER CORPORATION
・AGILENT TECHNOLOGIES
・WATERS CORPORATION
・株式会社島津製作所
・BIO-RAD LABORATORIES
・BRUKER CORPORATION
・PERKINELMER
（その他企業）
・MERCK KGAA
・GE HEALTHCARE
・JANVIER LABS
・INGENIOUS TARGETING LABORATORY
・POLYGENE
・GVK BIO
・CYAGEN BIOSCIENCES
・DATA SCIENCES INTERNATIONAL
（全264頁）
【レポート詳細目次、データ項目一覧は当ページ下を参照ください】
英文詳細目次(table of contents)
【原文詳細目次】
In Vivo Toxicology Market by Product (Animal Models, Reagents & Kits), Test Type (Chronic, Sub-acute), Toxicity Endpoints (Systemic, Immunotoxicity), Testing Facility (Outsourced, In-house), End User (Academic & Research Institute, CROs) - Forecast to 2025
Table of Contents
1 INTRODUCTION 38
1.1 OBJECTIVES OF THE STUDY 38
1.2 MARKET DEFINITION 38
1.2.1 INCLUSIONS & EXCLUSIONS OF THE STUDY 38
1.3 MARKET SCOPE 39
1.3.1 MARKETS COVERED 39
・ FIGURE 1 IN VIVO TOXICOLOGY MARKET SEGMENTATION 39
1.3.2 YEARS CONSIDERED FOR THE STUDY 40
1.4 CURRENCY 40
1.5 LIMITATIONS 40
1.6 STAKEHOLDERS 40
1.7 SUMMARY OF CHANGES 41
2 RESEARCH METHODOLOGY 42
2.1 RESEARCH DATA 42
2.1.1 SECONDARY DATA 42
2.1.2 PRIMARY DATA 43
・ FIGURE 2 BREAKDOWN OF PRIMARIES: IN VIVO TOXICOLOGY MARKET 43
2.1.3 MARKET DATA ESTIMATION & TRIANGULATION 44
・ FIGURE 3 DATA TRIANGULATION METHODOLOGY 44
2.2 MARKET ESTIMATION METHODOLOGY 45
・ FIGURE 4 MARKET SIZE ESTIMATION (COMPANY REVENUE ANALYSIS-BASED ESTIMATION) 45
・ FIGURE 5 IN VIVO TOXICOLOGY MARKET SIZE (USD MILLION) 45
・ FIGURE 6 IN VIVO TOXICOLOGY MARKET: GROWTH RATE OF TOP COMPANIES (2017−2019) 46
・ FIGURE 7 IN VIVO TOXICOLOGY MARKET: FINAL CAGR PROJECTIONS (2020−2025) 46
・ FIGURE 8 IN VIVO TOXICOLOGY MARKET: CAGR PROJECTIONS FROM THE ANALYSIS OF DEMAND-SIDE DRIVERS AND OPPORTUNITIES 47
2.3 INDUSTRY INSIGHTS 48
2.4 ASSUMPTIONS FOR THE STUDY 48
3 EXECUTIVE SUMMARY 49
・ FIGURE 9 IN VIVO TOXICOLOGY MARKET, BY PRODUCT, 2020 VS. 2025 (USD MILLION) 49
・ FIGURE 10 IN VIVO TOXICOLOGY MARKET, BY TEST TYPE, 2020 VS. 2025 (USD MILLION) 50
・ FIGURE 11 GEOGRAPHICAL SNAPSHOT OF THE IN VIVO TOXICOLOGY MARKET 51
4 PREMIUM INSIGHTS 52
4.1 IN VIVO TOXICOLOGY MARKET OVERVIEW 52
・ FIGURE 12 INCREASING PHARMACEUTICAL R&D ACTIVITIES TO DRIVE MARKET GROWTH 52
4.2 IN VIVO TOXICOLOGY MARKET SHARE, BY TOXICITY ENDPOINT, 2020 VS. 2025 52
・ FIGURE 13 IMMUNOTOXICITY SEGMENT TO ACCOUNT FOR THE LARGEST MARKET SHARE IN 2025 52
4.3 IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY, 2020 VS. 2025 (USD MILLION) 53
・ FIGURE 14 OUTSOURCED TESTING FACILITIES SEGMENT TO REGISTER THE HIGHEST GROWTH IN THE FORECAST PERIOD 53
4.4 IN VIVO TOXICOLOGY MARKET SHARE, BY END USER, 2020 VS. 2025 53
・ FIGURE 15 ACADEMIC & RESEARCH INSTITUTES ARE THE LARGEST END USERS OF IN VIVO TOXICOLOGY PRODUCTS 53
5 MARKET OVERVIEW 54
5.1 MARKET DYNAMICS 54
・ FIGURE 16 IN VIVO TOXICOLOGY MARKET: DRIVERS, RESTRAINTS, OPPORTUNITIES, AND CHALLENGES 54
5.1.1 DRIVERS 55
5.1.1.1 INCREASING PHARMACEUTICAL R&D ACTIVITIES 55
・ TABLE 1 R&D INVESTMENTS OF NOTE 55
5.1.1.2 INNOVATIONS IN ANIMAL MODELS 56
・ TABLE 2 INNOVATIVE ANIMAL MODELS DEVELOPED AND LAUNCHED BY PLAYERS 56
5.1.1.3 EXCLUSIVE IN VIVO TOXICOLOGY TESTS 56
5.1.1.4 INCREASING DEMAND FOR PERSONALIZED MEDICINE 57
5.1.2 RESTRAINTS 57
5.1.2.1 ALTERNATIVES TO ANIMAL TESTING 57
5.1.3 OPPORTUNITIES 58
5.1.3.1 RISING DEMAND FOR HUMANIZED ANIMAL MODELS 58
5.1.4 CHALLENGES 58
5.1.4.1 REGULATIONS AND LAWS FOR THE ETHICAL USE OF ANIMALS IN RESEARCH 58
5.2 IMPACT OF COVID-19 ON THE VIVO TOXICOLOGY MARKET 59
5.3 REGULATORY ASSESSMENT 59
5.3.1 INTRODUCTION 59
5.3.2 NORTH AMERICA 59
5.3.3 EUROPE 60
5.3.4 CHINA 61
5.3.5 JAPAN 62
5.3.6 INDIA 62
5.3.7 AUSTRALIA 63
5.3.8 BRAZIL 63
5.4 PATENT ANALYSIS 64
5.4.1 TOP EIGHT INSTITUTES WITH THE HIGHEST NO. OF PATENT FILINGS FOR ANIMAL MODELS IN THE LAST 10 YEARS 64
5.4.2 TOP 20 ACTIVE COUNTRIES IN PATENT FILING (ANIMAL MODELS) IN THE LAST 10 YEARS 64
5.4.3 FIELD OF STUDY IN PATENT FILING (ANIMAL MODELS) IN THE LAST 10 YEARS 65
5.5 TRADE ANALYSIS 65
5.5.1 TRADE ANALYSIS FOR CHROMATOGRAPHY AND ELECTROPHORESIS INSTRUMENTS 65
・ TABLE 3 IMPORT DATA FOR ELECTROPHORESIS AND CHROMATOGRAPHY INSTRUMENTS, BY COUNTRY, 2016–2020 (USD THOUSAND) 66
5.5.2 TRADE ANALYSIS FOR DIAGNOSTIC AND LABORATORY REAGENTS 67
・ TABLE 4 IMPORT DATA FOR DIAGNOSTIC AND LABORATORY REAGENTS, BY COUNTRY, 2016-2020 (USD THOUSAND) 67
5.6 PORTER’S FIVE FORCES ANALYSIS 68
・ TABLE 5 PORTER’S FIVE FORCES ANALYSIS 68
5.6.1 THREAT OF NEW ENTRANTS 68
5.6.2 THREAT OF SUBSTITUTES 68
5.6.3 BARGAINING POWER OF SUPPLIERS 69
5.6.4 BARGAINING POWER OF BUYERS 69
5.6.5 INTENSITY OF COMPETITIVE RIVALRY 69
5.7 SUPPLY CHAIN ANALYSIS 69
・ FIGURE 17 DIRECT DISTRIBUTION STRATEGY PREFERRED BY PROMINENT COMPANIES 70
5.7.1 KEY INFLUENCERS 70
5.8 VALUE CHAIN ANALYSIS 71
・ FIGURE 18 MAJOR VALUE IS ADDED DURING THE MANUFACTURING
AND ASSEMBLY PHASES 71
5.9 ECOSYSTEM ANALYSIS OF THE IN VIVO TOXICOLOGY MARKET 72
・ FIGURE 19 ECOSYSTEM ANALYSIS 72
6 IN VIVO TOXICOLOGY MARKET, BY PRODUCT 73
6.1 INTRODUCTION 74
・ TABLE 6 IN VIVO TOXICOLOGY MARKET, BY PRODUCT, 2018–2025 (USD MILLION) 74
6.2 CONSUMABLES 74
・ TABLE 7 IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES, BY TYPE,
2018–2025 (USD MILLION) 74
・ TABLE 8 IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES, BY REGION,
2018–2025 (USD MILLION) 75
・ TABLE 9 NORTH AMERICA: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES,
BY COUNTRY, 2018–2025 (USD MILLION) 75
・ TABLE 10 EUROPE: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES, BY COUNTRY, 2018–2025 (USD MILLION) 75
・ TABLE 11 ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES,
BY COUNTRY, 2018–2025 (USD MILLION) 76
・ TABLE 12 LATIN AMERICA: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES,
BY COUNTRY, 2018–2025 (USD MILLION) 76
6.2.1 REAGENTS & KITS 76
6.2.1.1 REAGENTS & KITS HOLD THE LARGEST SHARE OF THE CONSUMABLES MARKET 76
・ TABLE 13 IN VIVO TOXICOLOGY MARKET FOR REAGENTS & KITS, BY REGION,
2018–2025 (USD MILLION) 77
・ TABLE 14 NORTH AMERICA: IN VIVO TOXICOLOGY MARKET FOR REAGENTS & KITS,
BY COUNTRY, 2018–2025 (USD MILLION) 77
・ TABLE 15 EUROPE: IN VIVO TOXICOLOGY MARKET FOR REAGENTS & KITS, BY COUNTRY, 2018–2025 (USD MILLION) 77
・ TABLE 16 ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET FOR REAGENTS & KITS,
BY COUNTRY, 2018–2025 (USD MILLION) 78
・ TABLE 17 LATIN AMERICA: IN VIVO TOXICOLOGY MARKET FOR REAGENTS & KITS,
BY COUNTRY, 2018–2025 (USD MILLION) 78
6.2.2 ANIMAL MODELS 78
・ TABLE 18 IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE,
2018–2025 (USD MILLION) 79
・ TABLE 19 IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY REGION,
2018–2025 (USD MILLION) 79
・ TABLE 20 NORTH AMERICA: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS,
BY COUNTRY, 2018–2025 (USD MILLION) 79
・ TABLE 21 EUROPE: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY COUNTRY, 2018–2025 (USD MILLION) 80
・ TABLE 22 ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS,
BY COUNTRY, 2018–2025 (USD MILLION) 80
・ TABLE 23 LATIN AMERICA: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS,
BY COUNTRY, 2018–2025 (USD MILLION) 80
6.2.2.1 MICE MODELS 81
6.2.2.1.1 MICE MODELS ARE WIDELY USED IN IN VIVO TOXICITY TESTING 81
・ TABLE 24 PROMINENT MICE MODELS AVAILABLE IN THE MARKET 81
・ TABLE 25 IN VIVO TOXICOLOGY MARKET FOR MICE MODELS, BY REGION,
2018–2025 (USD MILLION) 82
・ TABLE 26 NORTH AMERICA: IN VIVO TOXICOLOGY MARKET FOR MICE MODELS,
BY COUNTRY, 2018–2025 (USD MILLION) 82
・ TABLE 27 EUROPE: IN VIVO TOXICOLOGY MARKET FOR MICE MODELS, BY COUNTRY, 2018–2025 (USD MILLION) 82
・ TABLE 28 ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET FOR MICE MODELS,
BY COUNTRY, 2018–2025 (USD MILLION) 83
・ TABLE 29 LATIN AMERICA: IN VIVO TOXICOLOGY MARKET FOR MICE MODELS,
BY COUNTRY, 2018–2025 (USD MILLION) 83
6.2.2.2 RAT MODELS 83
6.2.2.2.1 EASE OF PERFORMING SURGERY ON RAT MODELS AND DEVELOPMENT OF GENETICALLY MODIFIED RAT MODELS DRIVE THE MARKET 83
・ TABLE 30 IN VIVO TOXICOLOGY MARKET FOR RAT MODELS, BY REGION,
2018–2025 (USD MILLION) 84
・ TABLE 31 NORTH AMERICA: IN VIVO TOXICOLOGY MARKET FOR RAT MODELS,
BY COUNTRY, 2018–2025 (USD MILLION) 84
・ TABLE 32 EUROPE: IN VIVO TOXICOLOGY MARKET FOR RAT MODELS, BY COUNTRY, 2018–2025 (USD MILLION) 85
・ TABLE 33 ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET FOR RAT MODELS, BY COUNTRY, 2018–2025 (USD MILLION) 85
・ TABLE 34 LATIN AMERICA: IN VIVO TOXICOLOGY MARKET FOR RAT MODELS,
BY COUNTRY, 2018–2025 (USD MILLION) 85
6.2.2.3 OTHER ANIMAL MODELS 86
・ TABLE 35 GUINEA PIG AND HAMSTER MODELS: ADVANTAGES AND USAGE 86
・ TABLE 36 NON-RODENT ANIMAL MODELS: ADVANTAGES AND USAGE 87
・ TABLE 37 IN VIVO TOXICOLOGY MARKET FOR OTHER ANIMAL MODELS, BY REGION, 2018–2025 (USD MILLION) 87
・ TABLE 38 NORTH AMERICA: IN VIVO TOXICOLOGY MARKET FOR OTHER ANIMAL MODELS, BY COUNTRY, 2018–2025 (USD MILLION) 87
・ TABLE 39 EUROPE: IN VIVO TOXICOLOGY MARKET FOR OTHER ANIMAL MODELS,
BY COUNTRY, 2018–2025 (USD MILLION) 88
・ TABLE 40 ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET FOR OTHER ANIMAL MODELS, BY COUNTRY, 2018–2025 (USD MILLION) 88
・ TABLE 41 LATIN AMERICA: IN VIVO TOXICOLOGY MARKET FOR OTHER ANIMAL MODELS, BY COUNTRY, 2018–2025 (USD MILLION) 88
6.3 INSTRUMENTS 89
6.3.1 GROWING RESEARCH AND INTRODUCTION OF COMBINATION INSTRUMENTS ARE KEY GROWTH FACTORS 89
・ TABLE 42 IN VIVO TOXICOLOGY MARKET FOR INSTRUMENTS, BY REGION,
2018–2025 (USD MILLION) 89
・ TABLE 43 NORTH AMERICA: IN VIVO TOXICOLOGY MARKET FOR INSTRUMENTS,
BY COUNTRY, 2018–2025 (USD MILLION) 90
・ TABLE 44 EUROPE: IN VIVO TOXICOLOGY MARKET FOR INSTRUMENTS, BY COUNTRY, 2018–2025 (USD MILLION) 90
・ TABLE 45 ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET FOR INSTRUMENTS,
BY COUNTRY, 2018–2025 (USD MILLION) 90
・ TABLE 46 LATIN AMERICA: IN VIVO TOXICOLOGY MARKET FOR INSTRUMENTS,
BY COUNTRY, 2018–2025 (USD MILLION) 91
7 IN VIVO TOXICOLOGY MARKET, BY TEST TYPE 92
7.1 INTRODUCTION 93
・ TABLE 47 IN VIVO TOXICOLOGY MARKET, BY TEST TYPE, 2018–2025 (USD MILLION) 93
7.2 CHRONIC TOXICITY TESTING 93
7.2.1 CHRONIC TOXICITY TESTING IS ESSENTIAL FOR NEW DRUG ENTITY APPROVALS 93
・ TABLE 48 CHRONIC TOXICITY TESTING MARKET, BY REGION,
2018–2025 (USD MILLION) 94
・ TABLE 49 NORTH AMERICA: CHRONIC TOXICITY TESTING MARKET, BY COUNTRY,
2018–2025 (USD MILLION) 94
・ TABLE 50 EUROPE: CHRONIC TOXICITY TESTING MARKET, BY COUNTRY,
2018–2025 (USD MILLION) 94
・ TABLE 51 ASIA PACIFIC: CHRONIC TOXICITY TESTING MARKET, BY COUNTRY,
2018–2025 (USD MILLION) 95
・ TABLE 52 LATIN AMERICA: CHRONIC TOXICITY TESTING MARKET, BY COUNTRY,
2018–2025 (USD MILLION) 95
7.3 SUB-CHRONIC TOXICITY TESTING 95
7.3.1 SUB-CHRONIC TOXICITY TESTS PROVIDE DATA ON MANY PARAMETERS OF CHRONIC TOXICITY 95
・ TABLE 53 SUB-CHRONIC TOXICITY TESTING MARKET, BY REGION, 2018–2025 (USD MILLION) 96
・ TABLE 54 NORTH AMERICA: SUB-CHRONIC TOXICITY TESTING MARKET, BY COUNTRY, 2018–2025 (USD MILLION) 96
・ TABLE 55 EUROPE: SUB-CHRONIC TOXICITY TESTING MARKET, BY COUNTRY, 2018–2025 (USD MILLION) 96
・ TABLE 56 ASIA PACIFIC: SUB-CHRONIC TOXICITY TESTING MARKET, BY COUNTRY, 2018–2025 (USD MILLION) 97
・ TABLE 57 LATIN AMERICA: SUB-CHRONIC TOXICITY TESTING MARKET, BY COUNTRY, 2018–2025 (USD MILLION) 97
7.4 SUB-ACUTE TOXICITY TESTING 97
7.4.1 LONG OBSERVATION REQUIREMENTS AND HIGH ANIMAL SAMPLE SIZES ARE CHALLENGES ASSOCIATED WITH SUB-ACUTE TESTING 97
・ TABLE 58 SUB-ACUTE TOXICITY TESTING MARKET, BY REGION, 2018–2025 (USD MILLION) 98
・ TABLE 59 NORTH AMERICA: SUB-ACUTE TOXICITY TESTING MARKET, BY COUNTRY, 2018–2025 (USD MILLION) 98
・ TABLE 60 EUROPE: SUB-ACUTE TOXICITY TESTING MARKET, BY COUNTRY,
2018–2025 (USD MILLION) 98
・ TABLE 61 ASIA PACIFIC: SUB-ACUTE TOXICITY TESTING MARKET, BY COUNTRY,
2018–2025 (USD MILLION) 99
・ TABLE 62 LATIN AMERICA: SUB-ACUTE TOXICITY TESTING MARKET, BY COUNTRY, 2018–2025 (USD MILLION) 99
7.5 ACUTE TOXICITY TESTING 99
7.5.1 DISADVANTAGES OF ACUTE TOXICITY TESTING HAVE DRIVEN USE OF ALTERNATIVES 99
・ TABLE 63 ALTERNATIVE METHODS TO DETERMINE LD50 IN ACUTE TOXICITY TESTING 100
・ TABLE 64 ACUTE TOXICITY TESTING MARKET, BY REGION, 2018–2025 (USD MILLION) 100
・ TABLE 65 NORTH AMERICA: ACUTE TOXICITY TESTING MARKET, BY COUNTRY, 2018–2025 (USD MILLION) 100
・ TABLE 66 EUROPE: ACUTE TOXICITY TESTING MARKET, BY COUNTRY,
2018–2025 (USD MILLION) 101
・ TABLE 67 ASIA PACIFIC: ACUTE TOXICITY TESTING MARKET, BY COUNTRY,
2018–2025 (USD MILLION) 101
・ TABLE 68 LATIN AMERICA: ACUTE TOXICITY TESTING MARKET, BY COUNTRY,
2018–2025 (USD MILLION) 101
8 IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY 102
8.1 INTRODUCTION 103
・ TABLE 69 IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2018–2025 (USD MILLION) 103
8.2 OUTSOURCED TESTING FACILITIES 103
8.2.1 FOCUS ON COST CURTAILMENT AND NEED TO ACCESS SKILLED LABOR & EXPERTISE HAS BOOSTED OUTSOURCING 103
・ TABLE 70 IN VIVO TOXICOLOGY MARKET FOR OUTSOURCED TESTING FACILITIES,
BY REGION, 2018–2025 (USD MILLION) 104
・ TABLE 71 NORTH AMERICA: IN VIVO TOXICOLOGY MARKET FOR OUTSOURCED TESTING FACILITIES, BY COUNTRY, 2018–2025 (USD MILLION) 105
・ TABLE 72 EUROPE: IN VIVO TOXICOLOGY MARKET FOR OUTSOURCED TESTING FACILITIES, BY COUNTRY, 2018–2025 (USD MILLION) 105
・ TABLE 73 ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET FOR OUTSOURCED TESTING FACILITIES, BY COUNTRY, 2018–2025 (USD MILLION) 105
・ TABLE 74 LATIN AMERICA: IN VIVO TOXICOLOGY MARKET FOR OUTSOURCED TESTING FACILITIES, BY COUNTRY, 2018–2025 (USD MILLION) 106
8.3 IN-HOUSE TESTING FACILITIES 106
8.3.1 HIGH COSTS OF IN-HOUSE TESTING RESTRICT MARKET GROWTH 106
・ TABLE 75 IN VIVO TOXICOLOGY MARKET FOR IN-HOUSE TESTING FACILITIES, BY REGION, 2018–2025 (USD MILLION) 106
・ TABLE 76 NORTH AMERICA: IN VIVO TOXICOLOGY MARKET FOR IN-HOUSE TESTING FACILITIES, BY COUNTRY, 2018–2025 (USD MILLION) 107
・ TABLE 77 EUROPE: IN VIVO TOXICOLOGY MARKET FOR IN-HOUSE TESTING FACILITIES, BY COUNTRY, 2018–2025 (USD MILLION) 107
・ TABLE 78 ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET FOR IN-HOUSE TESTING FACILITIES, BY COUNTRY, 2018–2025 (USD MILLION) 107
・ TABLE 79 LATIN AMERICA: IN VIVO TOXICOLOGY MARKET FOR IN-HOUSE TESTING FACILITIES, BY COUNTRY, 2018–2025 (USD MILLION) 108
9 IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT 109
9.1 INTRODUCTION 110
・ TABLE 80 IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2018–2025 (USD MILLION) 110
9.2 IMMUNOTOXICITY 110
9.2.1 IMMUNOTOXICITY TESTING HOLDS THE LARGEST SHARE OF THE MARKET,
BY ENDPOINT 110
・ TABLE 81 IN VIVO TOXICOLOGY MARKET FOR IMMUNOTOXICITY, BY REGION,
2018–2025 (USD MILLION) 111
・ TABLE 82 NORTH AMERICA: IN VIVO TOXICOLOGY MARKET FOR IMMUNOTOXICITY,
BY COUNTRY, 2018–2025 (USD MILLION) 111
・ TABLE 83 EUROPE: IN VIVO TOXICOLOGY MARKET FOR IMMUNOTOXICITY, BY COUNTRY, 2018–2025 (USD MILLION) 111
・ TABLE 84 ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET FOR IMMUNOTOXICITY,
BY COUNTRY, 2018–2025 (USD MILLION) 112
・ TABLE 85 LATIN AMERICA: IN VIVO TOXICOLOGY MARKET FOR IMMUNOTOXICITY,
BY COUNTRY, 2018–2025 (USD MILLION) 112
9.3 SYSTEMIC TOXICITY 112
9.3.1 SYSTEMIC TOXICITY HELPS IDENTIFY A RANGE OF PARAMETERS IN PHARMA/BIOLOGIC TESTING 112
・ TABLE 86 IN VIVO TOXICOLOGY MARKET FOR SYSTEMIC TOXICITY, BY REGION,
2018–2025 (USD MILLION) 113
・ TABLE 87 NORTH AMERICA: IN VIVO TOXICOLOGY MARKET FOR SYSTEMIC TOXICITY,
BY COUNTRY, 2018–2025 (USD MILLION) 113
・ TABLE 88 EUROPE: IN VIVO TOXICOLOGY MARKET FOR SYSTEMIC TOXICITY,
BY COUNTRY, 2018–2025 (USD MILLION) 113
・ TABLE 89 ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET FOR SYSTEMIC TOXICITY,
BY COUNTRY, 2018–2025 (USD MILLION) 114
・ TABLE 90 LATIN AMERICA: IN VIVO TOXICOLOGY MARKET FOR SYSTEMIC TOXICITY,
BY COUNTRY, 2018–2025 (USD MILLION) 114
9.4 CARCINOGENICITY 114
9.4.1 RISING CANCER RESEARCH IS DRIVING THE MARKET FOR CARCINOGENICITY TESTING 114
・ TABLE 91 IN VIVO TOXICOLOGY MARKET FOR CARCINOGENICITY, BY REGION,
2018–2025 (USD MILLION) 115
・ TABLE 92 NORTH AMERICA: IN VIVO TOXICOLOGY MARKET FOR CARCINOGENICITY,
BY COUNTRY, 2018–2025 (USD MILLION) 115
・ TABLE 93 EUROPE: IN VIVO TOXICOLOGY MARKET FOR CARCINOGENICITY,
BY COUNTRY, 2018–2025 (USD MILLION) 115
・ TABLE 94 ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET FOR CARCINOGENICITY,
BY COUNTRY, 2018–2025 (USD MILLION) 116
・ TABLE 95 LATIN AMERICA: IN VIVO TOXICOLOGY MARKET FOR CARCINOGENICITY,
BY COUNTRY, 2018–2025 (USD MILLION) 116
9.5 GENOTOXICITY 116
9.5.1 GENOTOXICITY TESTING HELPS ISOLATE MUTATIVE SUBSTANCES 116
・ TABLE 96 TYPES OF GENOTOXICITY TESTS 117
・ TABLE 97 IN VIVO TOXICOLOGY MARKET FOR GENOTOXICITY, BY REGION,
2018–2025 (USD MILLION) 117
・ TABLE 98 NORTH AMERICA: IN VIVO TOXICOLOGY MARKET FOR GENOTOXICITY,
BY COUNTRY, 2018–2025 (USD MILLION) 118
・ TABLE 99 EUROPE: IN VIVO TOXICOLOGY MARKET FOR GENOTOXICITY, BY COUNTRY, 2018–2025 (USD MILLION) 118
・ TABLE 100 ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET FOR GENOTOXICITY,
BY COUNTRY, 2018–2025 (USD MILLION) 118
・ TABLE 101 LATIN AMERICA: IN VIVO TOXICOLOGY MARKET FOR GENOTOXICITY,
BY COUNTRY, 2018–2025 (USD MILLION) 119
9.6 DEVELOPMENTAL & REPRODUCTIVE TOXICITY 119
9.6.1 RISING PREVALENCE OF SEXUAL HEALTH & DEVELOPMENTAL ABNORMALITIES DRIVE MARKET GROWTH 119
・ TABLE 102 IN VIVO TOXICOLOGY MARKET FOR DART, BY REGION,
2018–2025 (USD MILLION) 119
・ TABLE 103 NORTH AMERICA: IN VIVO TOXICOLOGY MARKET FOR DART, BY COUNTRY, 2018–2025 (USD MILLION) 120
・ TABLE 104 EUROPE: IN VIVO TOXICOLOGY MARKET FOR DART, BY COUNTRY,
2018–2025 (USD MILLION) 120
・ TABLE 105 ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET FOR DART, BY COUNTRY,
2018–2025 (USD MILLION) 120
・ TABLE 106 LATIN AMERICA: IN VIVO TOXICOLOGY MARKET FOR DART, BY COUNTRY, 2018–2025 (USD MILLION) 121
9.7 OTHER TOXICITY ENDPOINTS 121
・ TABLE 107 IN VIVO TOXICOLOGY MARKET FOR OTHER TOXICITY ENDPOINTS, BY REGION, 2018–2025 (USD MILLION) 121
・ TABLE 108 NORTH AMERICA: IN VIVO TOXICOLOGY MARKET FOR OTHER TOXICITY ENDPOINTS, BY COUNTRY, 2018–2025 (USD MILLION) 122
・ TABLE 109 EUROPE: IN VIVO TOXICOLOGY MARKET FOR OTHER TOXICITY ENDPOINTS,
BY COUNTRY, 2018–2025 (USD MILLION) 122
・ TABLE 110 ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET FOR OTHER TOXICITY ENDPOINTS, BY COUNTRY, 2018–2025 (USD MILLION) 122
・ TABLE 111 LATIN AMERICA: IN VIVO TOXICOLOGY MARKET FOR OTHER TOXICITY ENDPOINTS, BY COUNTRY, 2018–2025 (USD MILLION) 123
10 IN VIVO TOXICOLOGY MARKET, BY END USER 124
10.1 INTRODUCTION 125
・ TABLE 112 IN VIVO TOXICOLOGY MARKET, BY END USER, 2018–2025 (USD MILLION) 125
10.2 ACADEMIC & RESEARCH INSTITUTES 125
10.2.1 GROWING PARTNERSHIPS AND HIGH USE OF INSTRUMENTS & CONSUMABLES DRIVE MARKET GROWTH 125
・ TABLE 113 IN VIVO TOXICOLOGY MARKET FOR ACADEMIC & RESEARCH INSTITUTES,
BY REGION, 2018–2025 (USD MILLION) 126
・ TABLE 114 NORTH AMERICA: IN VIVO TOXICOLOGY MARKET FOR ACADEMIC & RESEARCH INSTITUTES, BY COUNTRY, 2018–2025 (USD MILLION) 126
・ TABLE 115 EUROPE: IN VIVO TOXICOLOGY MARKET FOR ACADEMIC & RESEARCH INSTITUTES, BY COUNTRY, 2018–2025 (USD MILLION) 126
・ TABLE 116 ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET FOR ACADEMIC & RESEARCH INSTITUTES, BY COUNTRY, 2018–2025 (USD MILLION) 127
・ TABLE 117 LATIN AMERICA: IN VIVO TOXICOLOGY MARKET FOR ACADEMIC & RESEARCH INSTITUTES, BY COUNTRY, 2018–2025 (USD MILLION) 127
10.3 PHARMACEUTICAL & BIOTECHNOLOGY COMPANIES 127
10.3.1 GROWING IMPORTANCE OF PRECLINICAL TOXICOLOGY EVALUATION HAS INCREASED DEMAND FOR TESTING, ESPECIALLY IN PHARMA COMPANIES 127
・ TABLE 118 IN VIVO TOXICOLOGY MARKET FOR PHARMACEUTICAL & BIOTECHNOLOGY COMPANIES, BY REGION, 2018–2025 (USD MILLION) 128
・ TABLE 119 NORTH AMERICA: IN VIVO TOXICOLOGY MARKET FOR PHARMACEUTICAL & BIOTECHNOLOGY COMPANIES, BY COUNTRY, 2018–2025 (USD MILLION) 128
・ TABLE 120 EUROPE: IN VIVO TOXICOLOGY MARKET FOR PHARMACEUTICAL & BIOTECHNOLOGY COMPANIES, BY COUNTRY, 2018–2025 (USD MILLION) 129
・ TABLE 121 ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET FOR PHARMACEUTICAL & BIOTECHNOLOGY COMPANIES, BY COUNTRY, 2018–2025 (USD MILLION) 129
・ TABLE 122 LATIN AMERICA: IN VIVO TOXICOLOGY MARKET FOR PHARMACEUTICAL & BIOTECHNOLOGY COMPANIES, BY COUNTRY, 2018–2025 (USD MILLION) 129
10.4 CONTRACT RESEARCH ORGANIZATIONS 130
10.4.1 CONTRACT SERVICES HAVE REGISTERED RISING DEMAND DUE TO INCREASING COSTS OF RESEARCH 130
・ TABLE 123 IN VIVO TOXICOLOGY MARKET FOR CONTRACT RESEARCH ORGANIZATIONS, BY REGION, 2018–2025 (USD MILLION) 130
・ TABLE 124 NORTH AMERICA: IN VIVO TOXICOLOGY MARKET FOR CONTRACT RESEARCH ORGANIZATIONS, BY COUNTRY, 2018–2025 (USD MILLION) 130
・ TABLE 125 EUROPE: IN VIVO TOXICOLOGY MARKET FOR CONTRACT RESEARCH ORGANIZATIONS, BY COUNTRY, 2018–2025 (USD MILLION) 131
・ TABLE 126 ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET FOR CONTRACT RESEARCH ORGANIZATIONS, BY COUNTRY, 2018–2025 (USD MILLION) 131
・ TABLE 127 LATIN AMERICA: IN VIVO TOXICOLOGY MARKET FOR CONTRACT RESEARCH ORGANIZATIONS, BY COUNTRY, 2018–2025 (USD MILLION) 131
10.5 OTHER END USERS 132
・ TABLE 128 IN VIVO TOXICOLOGY MARKET FOR OTHER END USERS, BY REGION,
2018–2025 (USD MILLION) 132
・ TABLE 129 NORTH AMERICA: IN VIVO TOXICOLOGY MARKET FOR OTHER END USERS,
BY COUNTRY, 2018–2025 (USD MILLION) 133
・ TABLE 130 EUROPE: IN VIVO TOXICOLOGY MARKET FOR OTHER END USERS,
BY COUNTRY, 2018–2025 (USD MILLION) 133
・ TABLE 131 ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET FOR OTHER END USERS,
BY COUNTRY, 2018–2025 (USD MILLION) 133
・ TABLE 132 LATIN AMERICA: IN VIVO TOXICOLOGY MARKET FOR OTHER END USERS,
BY COUNTRY, 2018–2025 (USD MILLION) 134
11 IN VIVO TOXICOLOGY MARKET, BY REGION 135
11.1 INTRODUCTION 136
・ FIGURE 20 IN VIVO TOXICOLOGY MARKET SNAPSHOT 136
・ TABLE 133 IN VIVO TOXICOLOGY MARKET, BY REGION, 2018–2025 (USD MILLION) 136
11.2 NORTH AMERICA 137
・ FIGURE 21 NORTH AMERICA: IN VIVO TOXICOLOGY MARKET SNAPSHOT 137
・ TABLE 134 NORTH AMERICA: IN VIVO TOXICOLOGY MARKET, BY COUNTRY,
2018–2025 (USD MILLION) 138
・ TABLE 135 NORTH AMERICA: IN VIVO TOXICOLOGY MARKET, BY PRODUCT,
2018–2025 (USD MILLION) 138
・ TABLE 136 NORTH AMERICA: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES,
BY TYPE, 2018–2025 (USD MILLION) 138
・ TABLE 137 NORTH AMERICA: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS,
BY TYPE, 2018–2025 (USD MILLION) 139
・ TABLE 138 NORTH AMERICA: IN VIVO TOXICOLOGY MARKET, BY TEST TYPE,
2018–2025 (USD MILLION) 139
・ TABLE 139 NORTH AMERICA: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT, 2018–2025 (USD MILLION) 139
・ TABLE 140 NORTH AMERICA: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY, 2018–2025 (USD MILLION) 140
・ TABLE 141 NORTH AMERICA: IN VIVO TOXICOLOGY MARKET, BY END USER,
2018–2025 (USD MILLION) 140
11.2.1 US 140
11.2.1.1 GOVERNMENT FUNDING FOR LIFE SCIENCES RESEARCH DRIVES THE MARKET GROWTH IN THE US 140
・ TABLE 142 US: IN VIVO TOXICOLOGY MARKET, BY PRODUCT, 2018–2025 (USD MILLION) 141
・ TABLE 143 US: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES, BY TYPE,
2018–2025 (USD MILLION) 141
・ TABLE 144 US: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE,
2018–2025 (USD MILLION) 142
・ TABLE 145 US: IN VIVO TOXICOLOGY MARKET, BY TEST TYPE, 2018–2025 (USD MILLION) 142
・ TABLE 146 US: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2018–2025 (USD MILLION) 142
・ TABLE 147 US: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2018–2025 (USD MILLION) 143
・ TABLE 148 US: IN VIVO TOXICOLOGY MARKET, BY END USER,
2018–2025 (USD MILLION) 143
11.2.2 CANADA 143
11.2.2.1 GROWTH IN STEM CELL RESEARCH ACTIVITIES EXPECTED TO LEAD TO MARKET EXPANSION 143
・ TABLE 149 CANADA: IN VIVO TOXICOLOGY MARKET, BY PRODUCT,
2018–2025 (USD MILLION) 144
・ TABLE 150 CANADA: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES, BY TYPE, 2018–2025 (USD MILLION) 144
・ TABLE 151 CANADA: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE, 2018–2025 (USD MILLION) 144
・ TABLE 152 CANADA: IN VIVO TOXICOLOGY MARKET, BY TEST TYPE,
2018–2025 (USD MILLION) 145
・ TABLE 153 CANADA: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2018–2025 (USD MILLION) 145
・ TABLE 154 CANADA: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2018–2025 (USD MILLION) 145
・ TABLE 155 CANADA: IN VIVO TOXICOLOGY MARKET, BY END USER,
2018–2025 (USD MILLION) 146
11.3 EUROPE 146
・ TABLE 156 EUROPE: IN VIVO TOXICOLOGY MARKET, BY COUNTRY,
2018–2025 (USD MILLION) 146
・ TABLE 157 EUROPE: IN VIVO TOXICOLOGY MARKET, BY PRODUCT,
2018–2025 (USD MILLION) 147
・ TABLE 158 EUROPE: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES, BY TYPE, 2018–2025 (USD MILLION) 147
・ TABLE 159 EUROPE: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE, 2018–2025 (USD MILLION) 147
・ TABLE 160 EUROPE: IN VIVO TOXICOLOGY MARKET, BY TEST TYPE,
2018–2025 (USD MILLION) 148
・ TABLE 161 EUROPE: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2018–2025 (USD MILLION) 148
・ TABLE 162 EUROPE: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2018–2025 (USD MILLION) 148
・ TABLE 163 EUROPE: IN VIVO TOXICOLOGY MARKET, BY END USER,
2018–2025 (USD MILLION) 149
11.3.1 UK 149
11.3.1.1 INCREASING FOCUS ON CANCER RESEARCH IN THE UK IS A KEY MARKET GROWTH DRIVER 149
・ TABLE 164 UK: IN VIVO TOXICOLOGY MARKET, BY PRODUCT, 2018–2025 (USD MILLION) 149
・ TABLE 165 UK: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES, BY TYPE,
2018–2025 (USD MILLION) 150
・ TABLE 166 UK: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE,
2018–2025 (USD MILLION) 150
・ TABLE 167 UK: IN VIVO TOXICOLOGY MARKET, BY TEST TYPE, 2018–2025 (USD MILLION) 150
・ TABLE 168 UK: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2018–2025 (USD MILLION) 151
・ TABLE 169 UK: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2018–2025 (USD MILLION) 151
・ TABLE 170 UK: IN VIVO TOXICOLOGY MARKET, BY END USER,
2018–2025 (USD MILLION) 151
11.3.2 GERMANY 152
11.3.2.1 GERMANY ACCOUNTED FOR THE SECOND-LARGEST SHARE OF THE EUROPEAN MARKET 152
・ TABLE 171 GERMANY: IN VIVO TOXICOLOGY MARKET, BY PRODUCT,
2018–2025 (USD MILLION) 152
・ TABLE 172 GERMANY: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES, BY TYPE, 2018–2025 (USD MILLION) 152
・ TABLE 173 GERMANY: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE, 2018–2025 (USD MILLION) 153
・ TABLE 174 GERMANY: IN VIVO TOXICOLOGY MARKET, BY TEST TYPE,
2018–2025 (USD MILLION) 153
・ TABLE 175 GERMANY: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2018–2025 (USD MILLION) 153
・ TABLE 176 GERMANY: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2018–2025 (USD MILLION) 154
・ TABLE 177 GERMANY: IN VIVO TOXICOLOGY MARKET, BY END USER,
2018–2025 (USD MILLION) 154
11.3.3 FRANCE 154
11.3.3.1 INCREASED INVESTMENTS IN PROTEOMICS AND GENOMICS TO FUEL GROWTH OF MICE MODELS 154
・ TABLE 178 FRANCE: IN VIVO TOXICOLOGY MARKET, BY PRODUCT,
2018–2025 (USD MILLION) 155
・ TABLE 179 FRANCE: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES, BY TYPE, 2018–2025 (USD MILLION) 155
・ TABLE 180 FRANCE: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE, 2018–2025 (USD MILLION) 155
・ TABLE 181 FRANCE: IN VIVO TOXICOLOGY MARKET, BY TEST TYPE,
2018–2025 (USD MILLION) 156
・ TABLE 182 FRANCE: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2018–2025 (USD MILLION) 156
・ TABLE 183 FRANCE: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2018–2025 (USD MILLION) 156
・ TABLE 184 FRANCE: IN VIVO TOXICOLOGY MARKET, BY END USER,
2018–2025 (USD MILLION) 157
11.3.4 ITALY 157
11.3.4.1 GROWTH IN THE BIOTECHNOLOGY AND PHARMACEUTICAL INDUSTRIES TO DRIVE MARKET GROWTH 157
・ TABLE 185 ITALY: IN VIVO TOXICOLOGY MARKET, BY PRODUCT,
2018–2025 (USD MILLION) 157
・ TABLE 186 ITALY: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES, BY TYPE,
2018–2025 (USD MILLION) 158
・ TABLE 187 ITALY: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE,
2018–2025 (USD MILLION) 158
・ TABLE 188 ITALY: IN VIVO TOXICOLOGY MARKET, BY TEST TYPE,
2018–2025 (USD MILLION) 158
・ TABLE 189 ITALY: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2018–2025 (USD MILLION) 159
・ TABLE 190 ITALY: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2018–2025 (USD MILLION) 159
・ TABLE 191 ITALY: IN VIVO TOXICOLOGY MARKET, BY END USER,
2018–2025 (USD MILLION) 159
11.3.5 SPAIN 160
11.3.5.1 SHORT STUDY START-UP TIMES AND RISING R&D EXPENDITURE TO BOOST THE GROWTH OF THE SPANISH MARKET 160
・ TABLE 192 SPAIN: IN VIVO TOXICOLOGY MARKET, BY PRODUCT,
2018–2025 (USD MILLION) 160
・ TABLE 193 SPAIN: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES, BY TYPE,
2018–2025 (USD MILLION) 160
・ TABLE 194 SPAIN: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE,
2018–2025 (USD MILLION) 161
・ TABLE 195 SPAIN: IN VIVO TOXICOLOGY MARKET, BY TEST TYPE,
2018–2025 (USD MILLION) 161
・ TABLE 196 SPAIN: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2018–2025 (USD MILLION) 161
・ TABLE 197 SPAIN: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2018–2025 (USD MILLION) 162
・ TABLE 198 SPAIN: IN VIVO TOXICOLOGY MARKET, BY END USER,
2018–2025 (USD MILLION) 162
11.3.6 REST OF EUROPE 162
・ TABLE 199 ROE: IN VIVO TOXICOLOGY MARKET, BY PRODUCT,
2018–2025 (USD MILLION) 163
・ TABLE 200 ROE: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES,
BY TYPE, 2018–2025 (USD MILLION) 163
・ TABLE 201 ROE: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS,
BY TYPE, 2018–2025 (USD MILLION) 163
・ TABLE 202 ROE: IN VIVO TOXICOLOGY MARKET, BY TEST TYPE,
2018–2025 (USD MILLION) 164
・ TABLE 203 ROE: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2018–2025 (USD MILLION) 164
・ TABLE 204 ROE: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2018–2025 (USD MILLION) 164
・ TABLE 205 ROE: IN VIVO TOXICOLOGY MARKET, BY END USER,
2018–2025 (USD MILLION) 165
11.4 ASIA PACIFIC 165
・ FIGURE 22 ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET SNAPSHOT 166
・ TABLE 206 ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET, BY COUNTRY,
2018–2025 (USD MILLION) 167
・ TABLE 207 ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET, BY PRODUCT,
2018–2025 (USD MILLION) 167
・ TABLE 208 ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES, BY TYPE, 2018–2025 (USD MILLION) 167
・ TABLE 209 ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE, 2018–2025 (USD MILLION) 168
・ TABLE 210 ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET, BY TEST TYPE,
2018–2025 (USD MILLION) 168
・ TABLE 211 ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2018–2025 (USD MILLION) 168
・ TABLE 212 ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2018–2025 (USD MILLION) 169
・ TABLE 213 ASIA PACIFIC: IN VIVO TOXICOLOGY MARKET, BY END USER,
2018–2025 (USD MILLION) 169
11.4.1 CHINA 169
11.4.1.1 INTERNATIONAL ALLIANCES FOR R&D ARE DRIVING THE MARKET 169
・ TABLE 214 CHINA: IN VIVO TOXICOLOGY MARKET, BY PRODUCT,
2018–2025 (USD MILLION) 170
・ TABLE 215 CHINA: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES, BY TYPE,
2018–2025 (USD MILLION) 170
・ TABLE 216 CHINA: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE,
2018–2025 (USD MILLION) 170
・ TABLE 217 CHINA: IN VIVO TOXICOLOGY MARKET, BY TEST TYPE,
2018–2025 (USD MILLION) 171
・ TABLE 218 CHINA: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2018–2025 (USD MILLION) 171
・ TABLE 219 CHINA: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2018–2025 (USD MILLION) 171
・ TABLE 220 CHINA: IN VIVO TOXICOLOGY MARKET, BY END USER,
2018–2025 (USD MILLION) 172
11.4.2 JAPAN 172
11.4.2.1 INCREASING FOCUS ON PERSONALIZED DIAGNOSTICS PRODUCTS TO SUPPORT MARKET GROWTH 172
・ TABLE 221 JAPAN: IN VIVO TOXICOLOGY MARKET, BY PRODUCT,
2018–2025 (USD MILLION) 172
・ TABLE 222 JAPAN: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES, BY TYPE,
2018–2025 (USD MILLION) 173
・ TABLE 223 JAPAN: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE,
2018–2025 (USD MILLION) 173
・ TABLE 224 JAPAN: IN VIVO TOXICOLOGY MARKET, BY TEST TYPE,
2018–2025 (USD MILLION) 173
・ TABLE 225 JAPAN: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2018–2025 (USD MILLION) 174
・ TABLE 226 JAPAN: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2018–2025 (USD MILLION) 174
・ TABLE 227 JAPAN: IN VIVO TOXICOLOGY MARKET, BY END USER,
2018–2025 (USD MILLION) 174
11.4.3 INDIA 175
11.4.3.1 ROBUST GROWTH IN THE BIOTECH INDUSTRY IN INDIA TO BOOST THE MARKET GROWTH 175
・ TABLE 228 INDIA: IN VIVO TOXICOLOGY MARKET, BY PRODUCT,
2018–2025 (USD MILLION) 175
・ TABLE 229 INDIA: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES, BY TYPE,
2018–2025 (USD MILLION) 175
・ TABLE 230 INDIA: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE,
2018–2025 (USD MILLION) 176
・ TABLE 231 INDIA: IN VIVO TOXICOLOGY MARKET, BY TEST TYPE,
2018–2025 (USD MILLION) 176
・ TABLE 232 INDIA: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2018–2025 (USD MILLION) 176
・ TABLE 233 INDIA: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2018–2025 (USD MILLION) 177
・ TABLE 234 INDIA: IN VIVO TOXICOLOGY MARKET, BY END USER,
2018–2025 (USD MILLION) 177
11.4.4 REST OF ASIA PACIFIC 177
・ TABLE 235 ROAPAC: IN VIVO TOXICOLOGY MARKET, BY PRODUCT,
2018–2025 (USD MILLION) 178
・ TABLE 236 ROAPAC: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES, BY TYPE, 2018–2025 (USD MILLION) 178
・ TABLE 237 ROAPAC: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE, 2018–2025 (USD MILLION) 178
・ TABLE 238 ROAPAC: IN VIVO TOXICOLOGY MARKET, BY TEST TYPE,
2018–2025 (USD MILLION) 179
・ TABLE 239 ROAPAC: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2018–2025 (USD MILLION) 179
・ TABLE 240 ROAPAC: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2018–2025 (USD MILLION) 179
・ TABLE 241 ROAPAC: IN VIVO TOXICOLOGY MARKET, BY END USER,
2018–2025 (USD MILLION) 180
11.5 LATIN AMERICA 180
・ TABLE 242 LATIN AMERICA: IN VIVO TOXICOLOGY MARKET, BY COUNTRY,
2018–2025 (USD MILLION) 180
・ TABLE 243 LATIN AMERICA: IN VIVO TOXICOLOGY MARKET, BY PRODUCT,
2018–2025 (USD MILLION) 181
・ TABLE 244 LATIN AMERICA: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES, BY TYPE, 2018–2025 (USD MILLION) 181
・ TABLE 245 LATIN AMERICA: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS,
BY TYPE, 2018–2025 (USD MILLION) 181
・ TABLE 246 LATIN AMERICA: IN VIVO TOXICOLOGY MARKET, BY TEST TYPE,
2018–2025 (USD MILLION) 182
・ TABLE 247 LATIN AMERICA: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT, 2018–2025 (USD MILLION) 182
・ TABLE 248 LATIN AMERICA: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2018–2025 (USD MILLION) 182
・ TABLE 249 LATIN AMERICA: IN VIVO TOXICOLOGY MARKET, BY END USER,
2018–2025 (USD MILLION) 183
11.5.1 BRAZIL 183
11.5.1.1 GROWING BIOLOGICS SECTOR IN THE COUNTRY TO DRIVE THE MARKET 183
・ TABLE 250 BRAZIL: IN VIVO TOXICOLOGY MARKET, BY PRODUCT,
2018–2025 (USD MILLION) 183
・ TABLE 251 BRAZIL: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES, BY TYPE,
2018–2025 (USD MILLION) 184
・ TABLE 252 BRAZIL: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE, 2018–2025 (USD MILLION) 184
・ TABLE 253 BRAZIL: IN VIVO TOXICOLOGY MARKET, BY TEST TYPE,
2018–2025 (USD MILLION) 184
・ TABLE 254 BRAZIL: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2018–2025 (USD MILLION) 185
・ TABLE 255 BRAZIL: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2018–2025 (USD MILLION) 185
・ TABLE 256 BRAZIL: IN VIVO TOXICOLOGY MARKET, BY END USER,
2018–2025 (USD MILLION) 185
11.5.2 MEXICO 186
11.5.2.1 FAVORABLE BUSINESS ENVIRONMENT FOR MARKET PLAYERS TO SUPPORT MARKET GROWTH 186
・ TABLE 257 MEXICO: IN VIVO TOXICOLOGY MARKET, BY PRODUCT,
2018–2025 (USD MILLION) 186
・ TABLE 258 MEXICO: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES, BY TYPE,
2018–2025 (USD MILLION) 186
・ TABLE 259 MEXICO: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE, 2018–2025 (USD MILLION) 187
・ TABLE 260 MEXICO: IN VIVO TOXICOLOGY MARKET, BY TEST TYPE,
2018–2025 (USD MILLION) 187
・ TABLE 261 MEXICO: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2018–2025 (USD MILLION) 187
・ TABLE 262 MEXICO: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2018–2025 (USD MILLION) 188
・ TABLE 263 MEXICO: IN VIVO TOXICOLOGY MARKET, BY END USER,
2018–2025 (USD MILLION) 188
11.5.3 REST OF LATIN AMERICA 188
・ TABLE 264 ROLATAM: IN VIVO TOXICOLOGY MARKET, BY PRODUCT,
2018–2025 (USD MILLION) 188
・ TABLE 265 ROLATAM: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES, BY TYPE, 2018–2025 (USD MILLION) 189
・ TABLE 266 ROLATAM: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE, 2018–2025 (USD MILLION) 189
・ TABLE 267 ROLATAM: IN VIVO TOXICOLOGY MARKET, BY TEST TYPE,
2018–2025 (USD MILLION) 189
・ TABLE 268 ROLATAM: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT,
2018–2025 (USD MILLION) 190
・ TABLE 269 ROLATAM: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY,
2018–2025 (USD MILLION) 190
・ TABLE 270 ROLATAM: IN VIVO TOXICOLOGY MARKET, BY END USER,
2018–2025 (USD MILLION) 190
11.6 MIDDLE EAST & AFRICA 191
11.6.1 INFRASTRUCTURAL DEVELOPMENT TO CONTRIBUTE TO MARKET GROWTH IN THE MEA 191
・ TABLE 271 MIDDLE EAST & AFRICA: IN VIVO TOXICOLOGY MARKET, BY PRODUCT,
2018–2025 (USD MILLION) 191
・ TABLE 272 MIDDLE EAST & AFRICA: IN VIVO TOXICOLOGY MARKET FOR CONSUMABLES, BY TYPE, 2018–2025 (USD MILLION) 191
・ TABLE 273 MIDDLE EAST & AFRICA: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY TYPE, 2018–2025 (USD MILLION) 192
・ TABLE 274 MIDDLE EAST & AFRICA: IN VIVO TOXICOLOGY MARKET, BY TEST TYPE,
2018–2025 (USD MILLION) 192
・ TABLE 275 MIDDLE EAST & AFRICA: IN VIVO TOXICOLOGY MARKET, BY TOXICITY ENDPOINT, 2018–2025 (USD MILLION) 193
・ TABLE 276 MIDDLE EAST & AFRICA: IN VIVO TOXICOLOGY MARKET, BY TESTING FACILITY, 2018–2025 (USD MILLION) 193
・ TABLE 277 MIDDLE EAST & AFRICA: IN VIVO TOXICOLOGY MARKET, BY END USER, 2018–2025 (USD MILLION) 193
12 COMPETITIVE LANDSCAPE 194
12.1 INTRODUCTION 194
12.2 MARKET SHARE ANALYSIS (2019) 194
・ FIGURE 23 IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS, BY KEY PLAYER, 2019 194
12.2.1 ENVIGO (US) 195
12.3 MARKET RANKING ANALYSIS 196
・ FIGURE 24 COMPANY RANKING IN THE IN VIVO TOXICOLOGY INSTRUMENTS MARKET, 2019 196
12.4 MARKET EVALUATION FRAMEWORK (ANIMAL MODELS) 197
・ TABLE 278 MARKET EVALUATION FRAMEWORK: PRODUCT LAUNCHES WAS THE MAJOR STRATEGY ADOPTED BY PLAYERS 197
12.5 COMPETITIVE SCENARIO 197
12.5.1 KEY PRODUCT LAUNCHES 197
12.5.2 KEY ACQUISITIONS 198
12.5.3 KEY COLLABORATIONS 198
12.5.4 KEY EXPANSIONS 198
12.6 MARKET EVALUATION FRAMEWORK (INSTRUMENTS) 199
12.6.1 KEY MARKET DEVELOPMENTS 199
12.6.1.1 PRODUCT LAUNCHES 199
12.6.1.2 ACQUISITIONS 199
12.6.1.3 PARTNERSHIPS, COLLABORATIONS, AND AGREEMENTS 200
12.6.1.4 EXPANSIONS 200
12.7 COMPANY PRODUCT FOOTPRINT 201
・ TABLE 279 PRODUCT PORTFOLIO ANALYSIS: IN VIVO TOXICOLOGY MARKET (ANIMAL MODELS) 201
12.8 COMPANY GEOGRAPHIC FOOTPRINT 202
・ TABLE 280 GEOGRAPHIC REVENUE MIX: IN VIVO TOXICOLOGY MARKET (2019) 202
12.9 REVENUE ANALYSIS OF KEY MARKET PLAYERS 203
・ FIGURE 25 REVENUE ANALYSIS: IN VIVO TOXICOLOGY MARKET (2019) 203
12.10 COMPETITIVE LEADERSHIP MAPPING: IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS 204
12.10.1 STARS 204
12.10.2 EMERGING LEADERS 204
12.10.3 PERVASIVE PLAYERS 204
12.10.4 PARTICIPANTS 205
・ FIGURE 26 IN VIVO TOXICOLOGY MARKET FOR ANIMAL MODELS: COMPANY EVALUATION MATRIX, 2019 205
12.11 COMPETITIVE LEADERSHIP MAPPING: IN VIVO TOXICOLOGY MARKET FOR INSTRUMENTS 206
12.11.1 STARS 206
12.11.2 EMERGING LEADERS 206
12.11.3 PERVASIVE PLAYERS 206
12.11.4 PARTICIPANTS 206
・ FIGURE 27 IN VIVO TOXICOLOGY MARKET FOR INSTRUMENTS: COMPANY EVALUATION MATRIX, 2019 207
13 COMPANY PROFILES 208
13.1 MAJOR PLAYERS 208
(BUSINESS OVERVIEW, PRODUCTS OFFERED, RECENT DEVELOPMENTS, MNM VIEW)*
13.1.1 CHARLES RIVER LABORATORIES 208
・ TABLE 281 CHARLES RIVER LABORATORIES: BUSINESS OVERVIEW 208
・ FIGURE 28 CHARLES RIVER LABORATORIES: COMPANY SNAPSHOT (2019) 209
13.1.2 THE JACKSON LABORATORY 212
・ TABLE 282 THE JACKSON LABORATORY: BUSINESS OVERVIEW 212
・ FIGURE 29 THE JACKSON LABORATORY: COMPANY SNAPSHOT (2019) 212
13.1.3 ENVIGO 215
・ TABLE 283 ENVIGO: BUSINESS OVERVIEW 215
13.1.4 TACONIC BIOSCIENCES 218
・ TABLE 284 TACONIC BIOSCIENCES, INC.: BUSINESS OVERVIEW 218
13.1.5 GENOWAY 221
・ TABLE 285 GENOWAY: BUSINESS OVERVIEW 221
・ FIGURE 30 GENOWAY: COMPANY SNAPSHOT (2019) 221
13.1.6 HARBOUR BIOMED 224
・ TABLE 286 HARBOUR BIOMED: BUSINESS OVERVIEW 224
13.1.7 CROWN BIOSCIENCE 225
・ TABLE 287 CROWN BIOSCIENCE, INC.: BUSINESS OVERVIEW 225
13.1.8 TRANSCURE BIOSERVICES 228
・ TABLE 288 TRANSCURE BIOSERVICES: BUSINESS OVERVIEW 228
13.1.9 OZGENE PTY LTD. 229
・ TABLE 289 OZGENE PTY LTD.: BUSINESS OVERVIEW 229
13.1.10 THERMO FISHER SCIENTIFIC 230
・ TABLE 290 THERMO FISHER SCIENTIFIC, INC.: BUSINESS OVERVIEW 230
・ FIGURE 31 THERMO FISHER SCIENTIFIC, INC.: COMPANY SNAPSHOT (2019) 231
13.1.11 DANAHER CORPORATION 236
・ TABLE 291 DANAHER CORPORATION: BUSINESS OVERVIEW 236
・ FIGURE 32 DANAHER CORPORATION: COMPANY SNAPSHOT (2019) 236
13.1.12 AGILENT TECHNOLOGIES 239
・ TABLE 292 AGILENT TECHNOLOGIES: BUSINESS OVERVIEW 239
・ FIGURE 33 AGILENT TECHNOLOGIES, INC.: COMPANY SNAPSHOT (2019) 239
13.1.13 WATERS CORPORATION 243
・ TABLE 293 WATERS CORPORATION: BUSINESS OVERVIEW 243
・ FIGURE 34 WATERS CORPORATION: COMPANY SNAPSHOT (2019) 243
13.1.14 SHIMADZU CORPORATION 246
・ TABLE 294 SHIMADZU CORPORATION: BUSINESS OVERVIEW 246
・ FIGURE 35 SHIMADZU CORPORATION: COMPANY SNAPSHOT (2019) 246
13.1.15 BIO-RAD LABORATORIES 249
・ TABLE 295 BIO-RAD LABORATORIES, INC.: BUSINESS OVERVIEW 249
・ FIGURE 36 BIO-RAD LABORATORIES, INC.: COMPANY SNAPSHOT (2019) 250
13.1.16 BRUKER CORPORATION 251
・ TABLE 296 BRUKER CORPORATION: BUSINESS OVERVIEW 251
・ FIGURE 37 BRUKER CORPORATION: COMPANY SNAPSHOT (2019) 251
13.1.17 PERKINELMER 253
・ TABLE 297 PERKINELMER, INC.: BUSINESS OVERVIEW 253
・ FIGURE 38 PERKINELMER, INC.: COMPANY SNAPSHOT (2019) 253
13.2 OTHER PLAYERS 256
13.2.1 MERCK KGAA 256
・ TABLE 298 MERCK KGAA: BUSINESS OVERVIEW 256
・ FIGURE 39 MERCK KGAA: COMPANY SNAPSHOT (2019) 256
13.2.2 GE HEALTHCARE 258
・ TABLE 299 GE HEALTHCARE: BUSINESS OVERVIEW 258
・ FIGURE 40 GE HEALTHCARE: COMPANY SNAPSHOT (2019) 258
13.2.3 JANVIER LABS 260
・ TABLE 300 JANVIER LABS: BUSINESS OVERVIEW 260
13.2.4 INGENIOUS TARGETING LABORATORY 261
・ TABLE 301 INGENIOUS TARGETING LABORATORY: BUSINESS OVERVIEW 261
13.2.5 POLYGENE 263
・ TABLE 302 POLYGENE: BUSINESS OVERVIEW 263
13.2.6 GVK BIO 264
・ TABLE 303 GVK BIO: BUSINESS OVERVIEW 264
13.2.7 CYAGEN BIOSCIENCES 266
・ TABLE 304 CYAGEN BIOSCIENCES: BUSINESS OVERVIEW 266
13.2.8 DATA SCIENCES INTERNATIONAL 267
・ TABLE 305 DATA SCIENCE INTERNATIONAL: BUSINESS OVERVIEW 267
*BUSINESS OVERVIEW, PRODUCTS OFFERED, RECENT DEVELOPMENTS, MNM VIEW MIGHT NOT BE CAPTURED IN CASE OF UNLISTED COMPANIES.
14 APPENDIX 269
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