Organ and Tissue Transplantation and Alternatives

Table of Contents

Chapter 1 Introduction

Study Goals and Objectives
Reasons for Doing This Study
Scope of Report
Information Sources
Methodology
Geographic Breakdown
Analyst's Credentials
BCC Custom Research
Related BCC Research Reports

Chapter 2 Summary and Highlights

Chapter 3 Market and Technology Background

Organ and Tissue Transplantation and Alternatives
Cost of Care
Solid Organ Preservation
Immunosuppression
Organ Transplantation Alternatives
Trends in Organ and Tissue Transplantation Techniques and Their Alternatives

• 3D Tissue Assembly
• Nanotechnology for Tissue Regeneration
• Innovation by Small Firms

Chapter 4 Market Dynamics

Market Drivers

• Increasing Epidemiology of Different Diseases Influencing Organ Transplantations
• Rise in the Geriatric Population
• Rising Awareness of Importance of Organ and Tissue Donation
• New Therapeutic Pathways for Organ Transplantation and Their Alternatives

Market Restraints

• Challenges in Human Leukocyte Antigen (HLA) Sequencing
• Demand and Supply Gap

Market Opportunities

• Growing Economic Benefits of Organ and Tissue Transplants
• Improvement in Healthcare Infrastructure

Chapter 5 Market Breakdown by Product & Devices

Global Market for Organ and Tissue Transplantation and Alternatives
Alternative Technologies

• Market Size and Forecast
• Alternatives to Heart Transplantation
• Surgical
• Mechanical
• Total Artificial Heart
• Ventricular Assist Devices (VADs)
• Generations of Designs
• Orthopedic Alternatives

Tissue Products

• Market Size and Forecast

Immunosuppressants

• Market Size and Forecast

Solid Organ Preservation Solutions

• Market Size and Forecast
• Preservation Solutions in Development

Tissue Typing

• Market Size and Forecast

Chapter 6 Market Breakdown by Region

Global Market for Organ and Tissue Transplantation and Alternatives by Region
North America

• United States
• Canada
• Mexico

Europe

• Germany
• France
• U.K.
• Italy
• Spain
• Rest of Europe

Asia-Pacific

• Japan
• China
• India
• Australia and New Zealand
• Rest of Asia-Pacific

Rest of the World

• Market Analysis
• Brazil
• South Africa
• Rest of the World Countries

Chapter 7 Impact of COVID-19

Introduction

• Impact on Kidney Transplant Program
• Impact on Pharmaceutical Companies
• Donor Testing
• COVID-19 in Transplant Recipients
• Minimizing Infection Risk in Recipients
• Future Perspectives

Chapter 8 Overview of Donation Process

Introduction

• Black Market Donors
• The Transplantation Process
• Cost of Solid Organ Transplantation in the U.S.

Chapter 9 Regulations & Reimbursement

Regulations in the U.S.
U.S. Federal Regulation of Human Tissue
History of Regulation in the U.S.
Regulations Outside the U.S.
Reimbursement in the U.S.
Organ Acquisition Costs
Reimbursement for Hospital Costs
Reimbursement for Physician Services
Reimbursement for Immunosuppressants in the U.S.
Reimbursement Outside the U.S.
Treatment in EU Countries

Chapter 10 Competitive Landscape

Global Company Ranking Analysis
Mergers and Acquisitions
Agreements, Launches, Collaborations, and Partnerships

Chapter 11 Company Profiles

ABIOMED INC.
ABBVIE INC.
AMGEN INC.
ASTRAZENECA
BAYER AG
BRISTOL-MYERS SQUIBB
CAREDX INC.
F. HOFFMANN-LA ROCHE LTD.
JOHNSON & JOHNSON
MYLAN N.V.
NOVARTIS AG
PFIZER INC.
TRANSMEDICS INC.
VERTEX PHARMACEUTICALS INC.
XVIVO PERFUSION

Chapter 12 Appendix: Acronyms

List of Tables

Summary Table A : Global Market for Organ and Tissue Transplantation and Alternatives, by Product & Devices, Through 2024
Summary Table B : Global Market for Organ and Tissue Transplantation and Alternatives, by Region, Through 2024
Table 1 : MiMedx: Patent Portfolio
Table 2 : Product Launches in Transplant Diagnostics, 2012-2016
Table 3 : Global Market for Organ and Tissue Transplantation and Alternatives, by Product & Devices, Through 2024
Table 4 : Global Market for Alternative Technologies in Organ and Tissue Transplantation and Alternatives, Through 2024
Table 5 : Selected Global Commercial Opportunities for New Orthopedic Devices in the Future
Table 6 : Indications for Bioartificial Liver Transplantation
Table 7 : Global Market for Alternative Technologies in the Organ and Tissue Transplantation and Alternatives Market, by Region, Through 2024
Table 8 : Global Market for Tissue Products in the Organ and Tissue Transplantation and Alternatives Market, Through 2024
Table 9 : Cartilage and Soft Tissue Biologics and Biomaterials
Table 10 : Global Market of Tissue Products in Organ and Tissue Transplantation and Alternatives, by Region, Through 2024
Table 11 : Therapeutic Effects of Immunosuppressants
Table 12 : Global Market for Immunosuppressants in the Organ and Tissue Transplantation and Alternatives Market, Through 2024
Table 13 : Immunosuppressants, by Drug Class, Generic Name, Brand Name, and Manufacturer
Table 14 : Global Market of Immunosuppressants in the Organ and Tissue Transplantation and Alternatives, by Region, Through 2024
Table 15 : Cold Ischemia Time for Transplanted Organs
Table 16 : Global Market for Solid Organ Preservation Solutions in Organ and Tissue Transplantation and Alternatives, Through 2024
Table 17 : Optimal Preservation Solution Design
Table 18 : Major Organ Preservation Solutions
Table 19 : Global Market for Solid Organ Preservation Solutions in Organ and Tissue Transplantation and Alternatives, by Region, Through 2024
Table 20 : Tissue Typing Technologies
Table 21 : Global Market for Tissue Typing in Organ and Tissue Transplantation and Alternatives, Through 2024
Table 22 : Global Market for Tissue Typing in Organ and Tissue Transplantation and Alternatives, by Region, Through 2024
Table 23 : Global Market for Organ and Tissue Transplantation and Alternatives, by Region, Through 2024
Table 24 : North American Market for Organ and Tissue Transplantation and Alternatives, by Product & Devices, Through 2024
Table 25 : North American Market for Organ and Tissue Transplantation and Alternatives, by Country, Through 2024
Table 26 : European Market for Organ and Tissue Transplantation and Alternatives, by Product & Devices, Through 2024
Table 27 : European Market for Organ and Tissue Transplantation and Alternatives, by Country, Through 2024
Table 28 : Transplant Numbers in Germany, 2013-2019
Table 29 : Statistics for Cost of Bone Damage Repair and Related Disorders in Europe
Table 30 : Asia-Pacific Market for Organ and Tissue Transplantation and Alternatives, by Product & Devices, Through 2024
Table 31 : Asia-Pacific Market for Organ and Tissue Transplantation and Alternatives, by Country, Through 2024
Table 32 : Types of Organ Rejection After Transplant Procedures
Table 33 : Organ Transplantation Rates in Southeast Asian Countries, 2011-2014
Table 34 : Rest of the World Market for Organ and Tissue Transplantation and Alternatives, by Product & Devices, Through 2024
Table 35 : Registered Liver Transplantations (LT)/Kidney Transplantation in Middle East Countries, 2017
Table 36 : Rest of the World Market for Organ and Tissue Transplantation and Alternatives, by Country, Through 2024
Table 37 : Communicable and Noncommunicable Diseases Leading to Mortality in Brazil, 2018
Table 38 : Number of Organ Transplant Procedures in Brazil, by Type of Organ, 2015
Table 39 : Number of Organ Transplant Procedures in Turkey, by Type of Organ, 2019-2020
Table 40 : Pharmaceutical Company Efforts to Tackle COVID-19
Table 41 : U.S. Organ/Tissue Transplants: Total Estimated Transplants and Estimated Billed Charges, 2019
Table 42 : Immunosuppressive Drugs Currently Covered, by Medicare*
Table 43 : Overview of Medicare Immunosuppressive Drug Coverage
Table 44 : Selected Transplant Industry Acquisitions, 2010-Early 2015
Table 45 : Abiomed Inc: Product Portfolio
Table 46 : AbbVie: Product Portfolio
Table 47 : Amgen Inc.: Product Portfolio
Table 48 : AstraZeneca: Product Portfolio
Table 49 : Bayer AG: Product Portfolio
Table 50 : Bristol-Myers Squibb: Product Portfolio
Table 51 : CareDx Inc.: Product Portfolio
Table 52 : F. Hoffmann-La Roche & Co.: Product Portfolio
Table 53 : Johnson & Johnson: Immunosuppressants Product Portfolio
Table 54 : Mylan N.V.: Product Portfolio
Table 55 : Novartis AG: Product Portfolio
Table 56 : Pfizer Inc.: Product Portfolio
Table 57 : Pfizer Inc.: Pipeline Product Portfolio
Table 58 : Transmedics Inc.: Product Portfolio
Table 59 : Vertex Pharmaceuticals Inc.: Product Portfolio
Table 60 : XVIVO Perfusion: Product Portfolio
Table 61 : Acronyms Used in This Report

List of Figures

Summary Figure A : Global Market for Organ and Tissue Transplantation and Alternatives, by Product & Devices, 2018-2024
Summary Figure B : Global Market Shares of Organ and Tissue Transplantation and Alternatives, by Alternative Technologies, 2019
Summary Figure C : Global Market Shares for Organ and Tissue Transplantation and Alternatives, by Tissue Products, 2019
Summary Figure D : Global Market Shares for Organ and Tissue Transplantation and Alternatives, by Immunosuppressants, 2019
Summary Figure E : Global Market Shares for Organ and Tissue Transplantation and Alternatives, by Solid Organ Preservation Solutions, 2019
Figure 1 : Nanotechnology and Tissue Regeneration
Figure 2 : Number of Elderly (≥ 65 Years) Receiving Kidney Transplantation in the U.S., 2014-2018
Figure 3 : Number of Diabetes Patients Globally (20 to 79 Years of Age), 2000-2045
Figure 4 : Waiting List for Organs in the U.S., by Type of Organ, September 2020
Figure 5 : Number of Kidney Transplants, by Country, 2015
Figure 6 : Patients on Waiting List vs. Transplant Performed in the U.S., by Organ, 2019
Figure 7 : Global Market Shares of Organ and Tissue Transplantation and Alternatives, by Product & Devices, 2019
Figure 8 : Global Market for Alternative Technologies in Organ and Tissue Transplantation and Alternatives, 2018-2024
Figure 9 : Global Market Shares of Alternative Technologies in Organ and Tissue Transplantation and Alternatives, 2019
Figure 10 : Global Market Shares of Orthopedic Alternatives in Organ and Tissue Transplantation and Alternatives, 2019
Figure 11 : Global Market for Alternative Technologies in the Organ and Tissue Transplantation and Alternatives Market, by Region, 2018-2024
Figure 12 : Global Market for Tissue Products in the Organ and Tissue Transplantation and Alternatives Market, 2018-2024
Figure 13 : Global Market Shares for Tissue Products in the Organ and Tissue Transplantation and Alternatives Market, 2019
Figure 14 : Global Market Shares for Peripheral Blood Stem Cells, Cord Blood, Bone Marrow in the Organ and Tissue Transplantation and Alternatives Market, 2019
Figure 15 : Global Market Shares for Orthobiologics (Bone Allografts, Machined Bone, DBM) in the Organ and Tissue Transplantation and Alternatives Market, 2019
Figure 16 : Global Market of Tissue Products in Organ and Tissue Transplantation and Alternatives, by Region, 2018-2024
Figure 17 : Global Market for Immunosuppressants in the Organ and Tissue Transplantation and Alternatives, 2018-2024
Figure 18 : Global Market Shares for Immunosuppressants in the Organ and Tissue Transplantation and Alternatives Market, 2019
Figure 19 : Global Market Shares for Calcineurin Inhibitors in the Organ and Tissue Transplantation and Alternatives Market, 2019
Figure 20 : Global Market Shares for Anti-proliferative Agents in the Organ and Tissue Transplantation and Alternatives Market, 2019
Figure 21 : Global Market Shares for m-TOR Inhibitors in the Organ and Tissue Transplantation and Alternatives Market, 2019
Figure 22 : Global Market Shares for Polyclonal Antibodies in the Organ and Tissue Transplantation and Alternatives Market, 2019
Figure 23 : Global Market of Immunosuppressants in Organ and Tissue Transplantation and Alternatives, by Region, 2018-2024
Figure 24 : Global Market for Solid Organ Preservation Solutions in Organ and Tissue Transplantation and Alternatives, 2018-2024
Figure 25 : Global Market Shares for Solid Organ Preservation Solutions in Organ and Tissue Transplantation and Alternatives, 2019
Figure 26 : Global Market for Solid Organ Preservation Solutions in Organ and Tissue Transplantation and Alternatives, by Region, 2018-2024
Figure 27 : Global Market for Tissue Typing in Organ and Tissue Transplantation and Alternatives, 2018-2024
Figure 28 : Global Market for Tissue Typing in Organ and Tissue Transplantation and Alternatives, by Region, 2018-2024
Figure 29 : Global Market Shares of Organ and Tissue Transplantation and Alternatives, by Region, 2019
Figure 30 : North American Market Shares of Organ and Tissue Transplantation and Alternatives, by Product & Devices, 2019
Figure 31 : North American Market Shares of Organ and Tissue Transplantation and Alternatives, by Alternative Devices, 2019
Figure 32 : North American Market Shares of Organ and Tissue Transplantation and Alternatives, by Tissue Products, 2019
Figure 33 : North American Market Shares of Organ and Tissue Transplantation and Alternatives, by Immunosuppressants, 2019
Figure 34 : North American Market Shares of Organ and Tissue Transplantation and Alternatives, by Solid Organ Preservation Solutions, 2019
Figure 35 : North American Market Shares for Organ and Tissue Transplantation and Alternatives, by Country, 2019
Figure 36 : United States Market for Organ and Tissue Transplantation and Alternatives, 2018-2024
Figure 37 : Canadian Market for Organ and Tissue Transplantation and Alternatives, 2018-2024
Figure 38 : Mexican Market for Organ and Tissue Transplantation and Alternatives, 2018-2024
Figure 39 : European Market Shares of Organ and Tissue Transplantation and Alternatives, by Product & Devices, 2019
Figure 40 : European Market Shares of Organ and Tissue Transplantation and Alternatives, by Alternative Technologies, 2019
Figure 41 : European Market Shares of Organ and Tissue Transplantation and Alternatives, by Tissue Products, 2019
Figure 42 : European Market Shares of Organ and Tissue Transplantation and Alternatives, by Immunosuppressants, 2019
Figure 43 : European Market Shares of Organ and Tissue Transplantation and Alternatives, by Solid Organ Preservation Solutions, 2019
Figure 44 : European Market Shares of Organ and Tissue Transplantation and Alternatives, by Country, 2019
Figure 45 : German Market for Organ and Tissue Transplantation and Alternatives, 2018-2024
Figure 46 : French Market for Organ and Tissue Transplantation and Alternatives, 2018-2024
Figure 47 : U.K. Market for Organ and Tissue Transplantation and Alternatives, 2018-2024
Figure 48 : Italian Market for Organ and Tissue Transplantation and Alternatives, 2018-2024
Figure 49 : Spainish Market for Organ and Tissue Transplantation and Alternatives, 2018-2024
Figure 50 : Rest of Europe Market for Organ and Tissue Transplantation and Alternatives, 2018-2024
Figure 51 : Asia-Pacific Market Shares of Organ and Tissue Transplantation and Alternatives, by Product & Devices, 2019
Figure 52 : Asia-Pacific Market Shares of Organ and Tissue Transplantation and Alternatives, by Alternative Technologies, 2019
Figure 53 : Asia-Pacific Market Shares of Organ and Tissue Transplantation and Alternatives, by Tissue Products, 2019
Figure 54 : Asia-Pacific Market Shares of Organ and Tissue Transplantation and Alternatives, by Immunosuppressants, 2019
Figure 55 : Asia-Pacific Market Shares of Organ and Tissue Transplantation and Alternatives, by Solid Organ Preservation Solutions, 2019
Figure 56 : Asia-Pacific Market Shares of Organ and Tissue Transplantation and Alternatives, by Country, 2019
Figure 57 : Japanese Market for Organ and Tissue Transplantation and Alternatives, 2018-2024
Figure 58 : Chinese Market for Organ and Tissue Transplantation and Alternatives, 2018-2024
Figure 59 : Indian Market for Organ and Tissue Transplantation and Alternatives, 2018-2024
Figure 60 : Australia and New Zealand’s Market for Organ and Tissue Transplantation and Alternatives, 2018-2024
Figure 61 : Number of Organ Donations in Australia, by Type of Donor, 2015
Figure 62 : Rest of Asia-Pacific Market for Organ and Tissue Transplantation and Alternatives, 2018-2024
Figure 63 : Rest of the World Market Shares of Organ and Tissue Transplantation and Alternatives, by Products & Devices, 2019
Figure 64 : Rest of the World Market Shares of Organ and Tissue Transplantation and Alternatives, by Alternative Technologies, 2019
Figure 65 : Rest of the World Market Shares of Organ and Tissue Transplantation and Alternatives, by Tissue Products, 2019
Figure 66 : Rest of the World Market Shares of Organ and Tissue Transplantation and Alternatives, by Immunosuppressants, 2019
Figure 67 : Rest of the World Market Shares of Organ and Tissue Transplantation and Alternatives, by Solid Organ Preservation Solutions, 2019
Figure 68 : Rest of the World Market Shares of Organ and Tissue Transplantation and Alternatives, by Country, 2019
Figure 69 : Brazilian Market for Organ and Tissue Transplantation and Alternatives, 2018-2024
Figure 70 : South African Market for Organ and Tissue Transplantation and Alternatives, 2018-2024
Figure 71 : Rest of the World Countries Market for Organ and Tissue Transplantation and Alternatives, 2018-2024
Figure 72 : Steep Reduction in Organ Transplantation Seen During COVID-19
Figure 73 : Global Market Ranking in the Organ and Tissue Transplantation and Alternatives Market, by Pharmaceutical Company, 2019
Figure 74 : Global Market Ranking of Organ and Tissue Transplantation and Alternatives, by Diagnostic and Alternatives in the Organ Manufacturing Industry, 2019
Figure 75 : Abiomed Inc.: Annual Revenue, 2016-2020
Figure 76 : Abiomed Inc.: Revenue Shares for R&D, by Impella Devices, 2016-2020
Figure 77 : AbbVie: Annual Revenue, 2016-2019
Figure 78 : AbbVie: Revenue Shares, by Region/Country, 2019
Figure 79 : AbbVie: Revenue Shares, by Business Unit, 2019
Figure 80 : Amgen Inc.: Annual Revenue, 2016-2019
Figure 81 : Amgen Inc.: Revenue Shares, by Region/Country, 2019
Figure 82 : Amgen Inc.: Revenue Shares, by Products, 2019
Figure 83 : AstraZeneca: Annual Revenue, 2016-2019
Figure 84 : AstraZeneca: Revenue Shares, by Region/Country, 2019
Figure 85 : AstraZeneca: Revenue Shares, by Business Unit, 2019
Figure 86 : Bayer AG: Annual Revenue, 2016-2019
Figure 87 : Bayer AG: Revenue Shares, by Region, 2019
Figure 88 : Bayer AG: Revenue Shares, by Business Unit, 2019
Figure 89 : Bristol-Myers Squibb: Annual Revenue, 2016-2019
Figure 90 : Bristol-Myers Squibb: Revenue Shares, by Region/Country, 2019
Figure 91 : Bristol-Myers Squibb: Revenue Shares, by Brands, 2019
Figure 92 : CareDx Inc.: Annual Revenue, 2016-2019
Figure 93 : CareDx Inc.: Revenue Shares in Pharmaceutical Segment, by Region/Country, 2019
Figure 94 : CareDx Inc.: Revenue Shares, by Business Segment, 2019
Figure 95 : F. Hoffmann-La Roche & Co.: Annual Revenue, 2016-2019
Figure 96 : F. Hoffmann-La Roche & Co.: Revenue Shares in Pharmaceutical Segment, by Region/Country, 2019
Figure 97 : F. Hoffmann-La Roche & Co.: Revenue Shares, by Business Segment, 2019
Figure 98 : Johnson & Johnson: Annual Revenue, 2016-2019
Figure 99 : Johnson & Johnson: Revenue Shares, by Region/Country, 2019
Figure 100 : Johnson & Johnson: Revenue Shares, by Business Unit, 2019
Figure 101 : Mylan N.V.: Annual Revenue, 2016-2019
Figure 102 : Mylan N.V.: Revenue Shares, by Region, 2019
Figure 103 : Mylan N.V.: Revenue Shares, by Business Unit, 2019
Figure 104 : Novartis AG.: Annual Revenue, 2015-2019
Figure 105 : Novartis AG: Revenue Shares, by Region/Country, 2019
Figure 106 : Novartis AG: Revenue Shares, by Business Segment, 2019
Figure 107 : Pfizer Inc.: Annual Revenue, 2016-2019
Figure 108 : Pfizer Inc.: Revenue Shares, by Region/Country, 2019
Figure 109 : Pfizer Inc.: Revenue Shares, by Business Segment, 2019
Figure 110 : Transmedics Inc.: Annual Revenue, 2018 and 2019
Figure 111 : Transmedics Inc.: Revenue Shares, by OCS Product, 2019
Figure 112 : Transmedics Inc.: Revenue Shares, by Region/Country, 2019
Figure 113 : Vertex Pharmaceuticals Inc.: Annual Revenue, 2016-2019
Figure 114 : Vertex Pharmaceuticals Inc.: Research and Development Expense, 2017-2019
Figure 115 : Vertex Pharmaceuticals Inc.: Revenue Shares, by Business Segment, 2019
Figure 116 : XVIVO Perfusion: Annual Revenue, 2018 and 2019
Figure 117 : XVIVO Perfusion: Revenue Shares, by Region, 2019

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