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DNAシーケンシング:研究、応用および臨床用市場2026年予測

Global DNA Sequencing: Research, Applied and Clinical Markets

出版元:BCC ResearchLinkIcon出版元について
発行年:2021年7月
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【レポート紹介】
DNAシーケンシングの世界市場規模は2021年の157億ドルから、2026年には377億ドルへと急速な増加が予測されます。当レポートでは、DNAシーケンシングの市場概要、技術的背景、シーケンシング市場におけるイニシアティブ、COVID-19の影響、研究と応用分野、臨床用途、シーケンシング業界、DNAシーケンシング市場、国地域別市場分析、特許レビュー/状況、競合状況、主要企業プロフィールなどを盛り込み、概略以下の構成でお届けいたします。
【レポート構成概要】
◆イントロダクション
・調査目的
・調査対象
・調査手法

◆サマリーと調査ハイライト

◆市場概要
・DNAシーケンシング市場
・シーケンシング成長の原動力
・シーケンシング用途
・シーケンシング業界

◆技術的背景
・DNAの重要性
・遺伝的変異と分析
・シーケンシングの歴史
・シーケンシングテクノロジー
・サンガーシーケンシング
・次世代シーケンシング(NGS)
・情報技術
・ベースコーリング
・参照シーケンスに対するマッピング
・バリアント分析
・臨床シーケンシング技術の課題

◆シーケンシング市場におけるイニシアティブ
・R&D分野のイニシアティブおよびプログラム
・単一細胞研究
・人口シーケンシングプロジェクト

◆COVID-19の影響
・MedTechへの影響
・DNAシーケンシングへの影響

◆研究と応用分野
・研究開発用途
・応用分野

◆臨床用途
・がん
・メンデル遺伝病
・リプロダクティブヘルス
・微生物学および感染症
・複雑障害
・移植診断

◆シーケンシング業界
・シーケンシング機器
・ロングリードシーケンス
・ターゲット濃縮/増幅
・遺伝子編集
・シーケンシング情報学
・リキッドバイオプシーアッセイ
・リプロダクティブヘルス診断
・非侵襲的出生前検査(NIPT)
・農業産業
・消費者ゲノミクス産業
・DNAデータストレージ業界

◆DNAシーケンシング市場
・市場ダイナミクス(ドライバー)
・DNAシーケンシング市場
・臨床診断シーケンシング
・がんの臨床診断シーケンシング
・リプロダクティブヘルス
・移植

市場データ
市場予測データ各種掲載(2026)
・機器および消耗品、製品タイプ別
・サンプル準備、製品タイプ別
・フォーマット別
・シーケンシングサービス、エンドユーザー別
・用途別
・疾患分野別

◆DNAシーケンシング市場、地域別
・北米
・欧州
・アジア太平洋
・その他地域
※地域別に主要セグメント別の市場予測データ掲載(-2026)

◆特許レビュー/状況
・循環腫瘍細胞に関する特許
・エクソソームに関する特許
・無細胞DNAに関する特許
・バイオマーカーに関する特許
・シーケンシング関連の特許紛争

◆競合状況
・買収
・戦略的提携

◆DNAシーケンシングの主要企業プロフィール
ADMERA HEALTH
ADAPTIVE BIOTECHNOLOGIES INC.
AGILENT TECHNOLOGIES INC.
AMBRY GENETICS
ASURAGEN INC.
ATHENA DIAGNOSTICS INC.
BAYLOR GENETICS
BECTON, DICKINSON AND CO.
BERRY GENOMICS CO. LTD.
BGI SHENZHEN
BIODESIX INC.
BIO-RAD LABORATORIES INC.
CAREDX INC.
CARIS LIFE SCIENCES
※上記を含む全82社プロフィール掲載

(全296頁)


【レポート詳細目次、データ項目一覧は当ページ下を参照ください】

英文詳細目次(table of contents)

【原文詳細目次】

Global DNA Sequencing: Research, Applied and Clinical Markets

Table of Contents

Chapter 1 Introduction

Study Goals and Objectives
Reasons for Doing This Study
What's New in This Report
Scope of Report
Information Sources
Methodology
Geographic Breakdown
Analyst's Credentials
BCC Custom Research
Related BCC Research Reports

Chapter 2 Summary and Highlights

Chapter 3 Overview

Introduction
DNA Sequencing Markets
Sequencing Growth Driving Forces
Sequencing Applications
Sequencing Industry

Chapter 4 Technology Background

Importance of DNA
Genetic Variation and Analysis
History of Sequencing
Sequencing Technologies
Sanger Sequencing
Next-Generation Sequencing (NGS)

  • Short-Read Platforms
  • Long-Read Platforms

Informatics Technologies
Base Calling
Mapping to a Reference Sequence
Variant Analysis
Clinical Sequencing Technology Challenges

Chapter 5 Sequencing Initiatives

Sequencing Initiatives
R&D Initiatives and Programs

  • 1+ Million Genomes
  • Access to Comprehensive Genomic Profiling Coalition (ACGP)
  • Access to Treatment and Testing (ACTT)
  • Africa Pathogen Genomics Initiative
  • Blood Profiling Atlas
  • Cancer-ID
  • Cancer Moon Shots Program
  • China Precision Medicine Initiative
  • ClinGen
  • Early Cancer Detection Consortium
  • EpiFemCare
  • France Genomic Medicine Plan
  • Friends of Cancer Research Project
  • Genomic Medicine Sweden
  • HCA-Organoid
  • Human Cell Atlas
  • Human Immunomics Initiative
  • Immunomonitor Consortium
  • Integration of Imaging and Fluid-Based Tumor Monitoring in Cancer Therapy Program
  • Intervene
  • Liquid Biopsies and Imaging for Improved Cancer Care
  • Liquid Biopsy-Based Malignant Tumor Early Screening Technology Research and Development Project
  • Lung-Map
  • Matchmaker Exchange
  • Metagenomics and Metadesign of Subways and Urban Biomes (MetaSub)
  • Medical Genome Initiative
  • Million Veteran Program (MVP)
  • MIND (Molecular Integration in Neurological Diagnosis)
  • MedSeq
  • National Microbiome Initiative (NMI)
  • Next Generation Single Cell Analysis Program
  • Precision Medicine Initiative
  • Prospective Registry of Multiplex Testing (PROMPT)
  • Quality Assurance Initiative Pathology (QuIP) Initiative
  • TopMed (Trans Omics for Precision Medicine)
  • Treehouse Childhood Cancer Initiative
  • Very Rare Cancer Consortium (VRCC)
  • Worldwide Innovative Networking (WIN) Consortium

Single-Cell Research

  • Cambridge Single-Cell Analysis Core Facility
  • Harvard Medical School Single-Cell Core
  • Mayo Medical Genome Facility
  • National Center for Single-Cell Biology
  • Next-Generation Single-Cell Analysis Program
  • Single-Cell Analysis Core
  • UC San Francisco Single-Cell Analysis Center

Population Sequencing Projects

Chapter 6 Impact of COVID-19 Pandemic

Introduction
Impact on MedTech

  • Elective and Noncritical Procedures
  • Shift in Manufacturing
  • Regulatory Delays, Clinical Trials and Product Launches
  • Supply Chain Disruptions

Impact of COVID-19 on DNA Sequencing

Chapter 7 Research and Applied Applications

Introduction
Research and Development Applications
Applied Applications

  • Direct to Consumer
  • Biopharma
  • Agriculture
  • Forensics
  • Microbiome
  • Synthetic Biology

Chapter 8 Clinical Applications

Introduction
Cancer Applications
Mendelian Disorders Applications
Reproductive Health Applications
Microbiology and Infectious Disease Applications
Complex Disorders Applications
Transplant Diagnostics Applications

Chapter 9 Sequencing Industry

Introduction
Sequencing Instruments Industry

  • Companies

Long-Read Sequencing Industry
Target Enrichment and Amplification Industry
Gene Editing Industry
Sequencing Informatics Industry
Liquid Biopsy Assay Industry
Reproductive Health Diagnostics Industry
Noninvasive Prenatal Testing (NIPT) Industry
Agriculture Industry
Consumer Genomics Industry
DNA Data Storage Industry

Chapter 10 DNA Sequencing Markets

Market Dynamics

  • Market Drivers

Market for DNA Sequencing

  • Sequencing Services Market
  • Sample Prep Kits and Reagents Market
  • Informatics Market
  • Sequencing Instruments and Consumables Market
  • Agriculture Market
  • Biopharma Market
  • Consumer Genomics Market
  • Microbiology Market
  • Population Genomics Market
  • Synthetic Biology Market

Clinical Diagnostic Sequencing

  • Cardiology Market
  • Clinical Microbiology and Infectious Disease Market
  • Mendelian Disorders Market
  • Metabolic/Immune Disorders Market
  • Neurology Market
  • Oncology Market
  • Reproductive Health Market
  • Transplant Market

Cancer Clinical Diagnostics Sequencing

  • Lung Cancer
  • Breast Cancer
  • Colorectal Cancer
  • Pan-Cancer
  • Other Cancers
  • Oncology Screening/Early Detection
  • Oncology Diagnosis
  • Oncology Therapy Guidance
  • Oncology Monitoring

Reproductive Health

  • IVF
  • Newborn Screening
  • Carrier Screening
  • NIPT

Transplant
Geographical Markets

Chapter 11 Patent Review/ New Developments

Patents on Circulating Tumor Cells
Patents on Exosomes
Patents on Cell-Free DNA
Patents Related to Biomarkers
Sequencing-Related Patent Disputes

Chapter 12 Competitive Landscape

Acquisitions
Strategic Alliances

Chapter 13 Company Profiles

ADMERA HEALTH
ADAPTIVE BIOTECHNOLOGIES INC.
AGILENT TECHNOLOGIES INC.
AMBRY GENETICS
ASURAGEN INC.
ATHENA DIAGNOSTICS INC.
BAYLOR GENETICS
BECTON, DICKINSON AND CO.
BERRY GENOMICS CO. LTD.
BGI SHENZHEN
BIODESIX INC.
BIO-RAD LABORATORIES INC.
CAREDX INC.
CARIS LIFE SCIENCES
CEGAT GMBH
CELLMAX LIFE
CENTOGENE AG
COOPERSURGICAL INC.
CYGNUS BIOSCIENCES CO. LTD.
DANAHER CORP.
DARUI BIOTECHNOLOGY CO. LTD.
DEVYSER AB
DIACARTA INC.
DNA ELECTRONICS
ELECTRONIC BIOSCIENCES
EPIC SCIENCES INC.
EUROFINS SCIENTIFIC
FRY LABORATORIES LLC
GENAPSYS INC.
GENDX BV
GENE BY GENE LTD.
GENOMATIX SOFTWARE GMBH
GENOME PROFILING LLC
GOLDEN HELIX
GRANDOMICS BIOSCIENCES CO. LTD.
GUARDANT HEALTH INC.
HELIX OPCO LLC
HISTOGENETICS LLC
HTG MOLECULAR DIAGNOSTICS INC.
ILLUMINA INC.
INEX INNOVATIONS EXCHANGE PTE. LTD.
INIVATA LTD.
INTERPACE DIAGNOSTICS LLC
INVIVOSCRIBE INC.
IREPERTOIRE INC.
KEW INC.
LABORATORY CORP. OF AMERICA INC.
MACROGEN INC.
MDXHEALTH INC.
MERCK KGAA
MYRIAD GENETICS INC.
NATERA INC.
NEOGENOMICS LABORATORIES
NEW ENGLAND BIOLABS
NGENEBIO CO., LTD.
NOVOGENE CO. LTD.
NUGEN TECHNOLOGIES INC.
OMNISEQ CORP.
OXFORD NANOPORE TECHNOLOGIES LTD.
PACIFIC BIOSCIENCES OF CALIFORNIA INC.
PARADIGM DIAGNOSTICS INC.
PARSEQ LAB CO. LTD.
PERKINELMER INC.
PERSONAL GENOME DIAGNOSTICS INC.
PERSONALIS INC.
PREDICINE INC.
PREVENTIONGENETICS INC.
QIAGEN N.V.
QUANTUM BIOSYSTEMS INC.
QUEST DIAGNOSTICS INC.
REAL TIME GENOMICS INC.
ROCHE HOLDING AG
SEEKIN
SEQUENCING.COM
SEVEN BRIDGES GENOMICS INC.
SISTEMAS GENOMICOS SL
SOPHIA GENETICS
TAKARA BIO INC.
THERMO FISHER SCIENTIFIC INC.
UBIQUITY GENOMICS INC.
VORTEX BIOSCIENCES
YOURGENE HEALTH PLC

Chapter 14 Appendix: Acronyms

List of Tables

Summary Table : Global Market for DNA Sequencing, by Major Segment, Through 2026
Table 1 : Global Market for DNA Sequencing, by Product Type, Through 2026
Table 2 : Market for DNA Sequencing Growth Driving Forces
Table 3 : Sequencing End Users and Applications
Table 4 : Key Sequencing Industry Participants, by Sector
Table 5 : DNA Chemical Building Blocks
Table 6 : DNA Translation and Transcription
Table 7 : Long-Range DNA Structure
Table 8 : Genetic Variant Types
Table 9 : Molecular Diagnostic Technology Platforms
Table 10 : Genome Coverage of PCR, Microarray and NGS Technology Platforms
Table 11 : DNA Sequencing Historical Timeline
Table 12 : Sequencing Technology Development, 1990-2020
Table 13 : Cost to Sequence a Single Human Genome, 2001-2021
Table 14 : Sequencing Technology Summary
Table 15 : Summary of Sanger Sequencing
Table 16 : Improvements in Sanger Sequencing
Table 17 : NGS Technologies
Table 18 : Illumina NGS Workflow
Table 19 : Thermo Fisher Scientific NGS Workflow
Table 20 : NGS Bioinformatics Workflow
Table 21 : Sequence Annotation Steps
Table 22 : Future Challenges in Implementing Clinical NGS
Table 23 : Key Sequencing Research and Development Programs
Table 24 : Single-Cell Core Research Facilities
Table 25 : Population Sequencing Projects
Table 26 : Number of Sequencing Projects in GOLD Database, 2018-2020
Table 27 : Main Sequencing Applications
Table 28 : Genetic Analysis Platform Comparison
Table 29 : Sequencing Impact on Agricultural Product Classes
Table 30 : Key Applications in Forensics/Human Identity Sequencing
Table 31 : Key Applications in Microbial Sequencing
Table 32 : Genetic Testing Scope
Table 33 : Key Applications for Sequencing-Based Diagnostics
Table 34 : Cancer Applications
Table 35 : Mendelian Disorders Applications
Table 36 : Reproductive Health Screening Applications
Table 37 : Ethical Issues Associated with NIPT
Table 38 : Microbiology/Infectious Disease Applications
Table 39 : Complex Disorder Applications
Table 40 : Transplant Diagnostics Applications
Table 41 : Subsectors within the Sequencing Industries
Table 42 : NGS and 3GS Industry Company Positioning
Table 43 : Long-Read Sequencing Industry
Table 44 : NGS Target Enrichment Industry
Table 45 : Gene Editing Tools Industry
Table 46 : Agricultural Gene Editing Industry
Table 47 : Sequencing Informatics Industry
Table 48 : Liquid Biopsy Assay Industry: Company Focus
Table 49 : Example of NGS-Based Liquid Biopsy Market Differentiation
Table 50 : NIPT Industry
Table 51 : Key Players in Synthetic Biology Agriculture Industry
Table 52 : Players in Consumer Genomics Industry
Table 53 : Key Forces Driving Growth in Market for DNA Sequencing and Their Implications
Table 54 : Global Market for DNA Sequencing, by Format, Through 2026
Table 55 : Global Market for Sequencing Instruments and Consumables, by Product Type, Through 2026
Table 56 : Global Market for Sequencing Instruments and Consumables, by Product Generation, Through 2026
Table 57 : Global Market for Sample Preparation, by Product Type, Through 2026
Table 58 : Global Market for Sequencing Services, by End User, Through 2026
Table 59 : Global Market for Applied Sequencing Services, by Application, Through 2026
Table 60 : Global Market for Clinical Diagnostic Sequencing, by Disease Category, Through 2026
Table 61 : NGS-Based Dilated Cardiomyopathy Test Providers
Table 62 : NGS-Based Infectious Disease Landscape
Table 63 : Multiple Sclerosis Diagnostic Technologies
Table 64 : Limitations of Tissue Biopsy in Cancer Applications
Table 65 : National Institutes of Health Liquid Biopsy Early Detection Initiative
Table 66 : Clinical Trials on Lung Cancer Liquid Biopsies
Table 67 : Five-Year Survival Rate for Ovarian Cancer
Table 68 : MRI and Liquid Biopsy Methods
Table 69 : Early Detection Tissue of Origin Approaches
Table 70 : Global Market for DNA Sequencing, by Region, Through 2026
Table 71 : North American Market for DNA Sequencing, by Country, Through 2026
Table 72 : North American Market for DNA Sequencing, by Major Segment, Through 2026
Table 73 : European Market for DNA Sequencing, by Country, Through 2026
Table 74 : European Market for DNA Sequencing, by Major Segment, Through 2026
Table 75 : Asia-Pacific Market for DNA Sequencing, by Country, Through 2026
Table 76 : Asia-Pacific Market for DNA Sequencing, by Major Segment, Through 2026
Table 77 : Rest of the World Market for DNA Sequencing, by Major Segment, Through 2026
Table 78 : Patent Activity on Circulating Tumor Cells (CTCs), by Country/Region, January 2010–June 2020
Table 79 : Patent Activity on Exosomes, by Country/Region, January 2010–December 2020
Table 80 : Patent Activity on Cell-Free DNA, by Country/Region, January 2010–December 2020
Table 81 : Patent Activity on Cancer Biomarkers, by Country/Region, January 2010–December 2020
Table 82 : Status of NGS-Based Liquid Biopsy Patent Disputes
Table 83 : Sequencing Industry Acquisitions
Table 84 : Sequencing Industry Strategic Alliances
Table 85 : Acronyms Used in the DNA Sequencing Industry

List of Figures

Summary Figure : Global Market for DNA Sequencing, by Major Segment, 2020-2026
Figure 1 : Agilent: Annual Revenue, 2018–2020
Figure 2 : Agilent: Revenue Share, by Region, 2020
Figure 3 : Agilent: Revenue Share, by Segment, 2020
Figure 4 : BD: Annual Revenue, 2018-2020
Figure 5 : BD: Revenue Share, by Geography, 2020
Figure 6 : BD: Revenue Share, by Segment, 2020
Figure 7 : Bio-Rad: Annual Revenue, 2018–2020
Figure 8 : Bio-Rad: Revenue Share, by Segment, 2020
Figure 9 : Danaher Corp.: Annual Revenue, 2018-2020
Figure 10 : Danaher Corp.: Revenue Share, by Region, 2020
Figure 11 : Danaher Corp.: Revenue Share, by Segment, 2020
Figure 12 : Illumina Inc.: Annual Revenue, 2018–2020
Figure 13 : Illumina Inc.: Revenue Share, by Region/ Country, 2020
Figure 14 : Illumina Inc.: Revenue Share, by Segment, 2020
Figure 15 : Merck KGaA: Annual Revenue, 2019 and 2020
Figure 16 : Merck KGaA: Revenue Share, by Region, 2020
Figure 17 : Merck KGaA: Revenue Share, by Segment, 2020
Figure 18 : Thermo Fisher Scientific: Annual Revenue, 2019 and 2020
Figure 19 : Thermo Fisher Scientific: Revenue Share, by Segment, 2020



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