Bioinformatics: Technologies and Global Markets

Table of Contents

Chapter 1 Introduction

Study Goals and Objectives
Reasons for Doing This Study
Scope of Report
Information Sources
Methodology
Geographic Breakdown
Analyst's Credentials
BCC Custom Research
Related BCC Research Reports

Chapter 2 Summary and Highlights

Chapter 3 Market and Technology Background

Introduction
Biological Data Sources
Bioinformatics in Systems Biology
Bioinformatics in Precision Medicine
Bioinformatics in Drug Development
Cheminformatics
Next-Generation Sequencing
Bioinformatics in Metagenomics
Bioinformatics in Database Management Systems
Market Trends

• Precision Medicine and Biomarker Identification
• Cloud-Based Solutions
• Shift Toward Value-Based Care

Market Challenges

• Data Integration
• Data Reliability and Standardization
• End-to-End Workflows

Market Trends in Bioinformatics Tools and Software

• Purchasing Factors Analysis

Analyzing Experimental Data

Chapter 4 Research Funding for Bioinformatics

Research Grants
Public Funding
Private Funding

Chapter 5 Market Dynamics

Market Drivers

• New Discoveries in Biological Sciences
• Increasing Use of Bioinformatics Analytical Software
• New Antibody Technologies and Antibody Types
• Antibody-Based Drug Discovery and Development
• Developed and Increasing Research Areas
• Increased Government Funding in Emerging Markets
• Need for Further Human Genomic and Proteomic Research
• New Application-Focused Technology Platforms

Market Restraints

• Challenging Issues of Modeling Systems
• Ethical Concerns of Bioinformatics and Computational Genomics

Market Opportunities

• Market Expansion into Emerging Countries
• Development of Novel Bioinformatics and Drugs

Chapter 6 Market Breakdown by Application

Information Overload

• Data Volume
• Data Variety
• Data Velocity
• Data Veracity

Software Scalability and Validity
Global Market for Bioinformatics by Application

• Genomics
• Proteomics
• Transcriptomics
• Metabolomics
• Cheminformatics
• Pharmacogenomics
• Metagenomics
• Other Applications

Chapter 7 Market for Sequencing Services and Platforms

Global Market for Sequencing Services and Platforms

• Sequencing Services
• Sequencing Platforms

Chapter 8 Market Breakdown by Solution

Global Market for Bioinformatics by Solution

• Bioinformatic Tools and Database Services
• Database Management Services
• IT Hardware and Infrastructure

Chapter 9 Market Breakdown by End User

Global Market for Bioinformatics by End User

• Research
• Clinical and Medical
• Other End Users

Chapter 10 Market Breakdown by Region

Global Market for Bioinformatics by Region

• North America
• Europe
• Asia-Pacific
• Rest of the World

Chapter 11 Impact of COVID-19 on the Pharmaceutical/Biotechnology Industry

Short-Term Impact

• Change in Demand
• Shift of Communication and Promotions to Remote Interactions
• Research and Development Changes

Long-Term Impact

• Delayed Approvals for Non-COVID-Related Pharmaceutical/Biotech Products
• Self-Sufficiency in Pharma/Biotech Industry
• Pharmaceutical Industry Growth Slow-Down
• Changes in Consumption Trends in Health-Related Products

Chapter 12 Bioinformatics Applications in Pharmaceutical R&D

Introduction
Drug Discovery and Development Process

• Target Identification
• Target Validation
• Lead Identification
• Lead Optimization

Clinical Research: Drug Development

• Preclinical Experiments
• Investigational New Drug Applications
• Clinical Trials
• New Drug Application
• NDA Approval

Post-Launch Ongoing Studies and Phase IV Clinical Trials

• Electronic Health Records
• Mobile Health Technologies
• Recent Pharmaceutical and Bioinformatics Alliances and Partnerships

Conclusions

Chapter 13 Competitive Landscape

Global Company Market Ranking Analysis

Chapter 14 Company Profiles

3RD MILLENNIUM INC.
AGILENT TECHNOLOGIES INC.
BIOMATTERS LTD. GENEIOUS
BIO-RAD (ABD SEROTEC)
BIO-TECHNE
COMPUGEN LTD.
DASSAULT SYSTEMES BIOVIA
DNASTAR, INC.
GENEDATA AG
GENEVA BIOFORMATICS (GENEBIO) SA
GENOMATIX SOFTWARE GMBH
GNS HEALTHCARE INC.
GVK BIOSCIENCES PVT. LTD.
ILLUMINA INC.
INTE:LIGAND SOFTWARE ENTWICKLUNGS UND CONSULTING GMBH
MACVECTOR INC.
MOLECULAR CONNECTIONS PVT. LTD.
MOLECULAR NETWORKS GMBH
NONLINEAR DYNAMICS LTD.
OCIMUM BIOSOLUTIONS LTD.
PERKINELMER INFORMATICS INC.
PERSONALIS INC.
QLUCORE AB
REAL TIME GENOMICS INC.
SMARTGENE SERVICES SARL
SYNGENE INTERNATIONAL
THERMO FISHER SCIENTIFIC INC.
Chapter 15 Appendix: Acronyms

List of Tables

Summary Table : Global Market for Bioinformatics, by Application, Through 2025
Table 1 : Recommendations for NGS Bioinformatics Tools
Table 2 : Bioinformatics Tools Used for Metagenomics Analysis
Table 3 : DBMS Platforms in Bioinformatics
Table 4 : Growth in Selected EMBL-EBI Resources, 2015 and 2016
Table 5 : Public Funding Programs, 2012-2018
Table 6 : Global Market for Bioinformatics, by Application, Through 2025
Table 7 : Cloud-Based Bioinformatics Tools
Table 8 : Global Market for Bioinformatics in Genomics Applications, by Region, Through 2025
Table 9 : Global Market for Bioinformatics in Proteomics Applications, by Region, Through 2025
Table 10 : Global Market for Bioinformatics in Transcriptomics Applications, by Region, Through 2025
Table 11 : Commercially Available Metabolomics Software
Table 12 : Open Access Tools for Complex Liquid Chromatography-Mass Spectrometry Data Analysis
Table 13 : Global Market for Bioinformatics in Metabolomics Applications, by Region, Through 2025
Table 14 : Cheminformatics Software Solutions for Drug R&D
Table 15 : Global Market for Bioinformatics in Cheminformatics Applications, by Region, Through 2025
Table 16 : Pharmacogenomic Biomarkers in Drug Labeling
Table 17 : Recent Research on Biomarkers
Table 18 : Global Market for Bioinformatics in Pharmacogenomics Applications, by Region, Through 2025
Table 19 : Bioinformatic Tools and Databases Used in Pharmacogenomics
Table 20 : Bioinformatic Tools for Pharmacogenomic Studies
Table 21 : Global Market for Bioinformatics in Metagenomics Applications, by Region, Through 2025
Table 22 : Toxicogenomic Studies Planned or Ongoing, 2016
Table 23 : Global Market for Bioinformatics in Other Applications, by Region, Through 2025
Table 24 : Global Market for Sequencing Services and Platforms, Through 2025
Table 25 : Global Market for Sequencing Services, by Region, Through 2025
Table 26 : Sequence Analysis Software
Table 27 : Global Market for Sequencing Platforms, by Region, Through 2025
Table 28 : Sequence Alignment Platforms
Table 29 : Global Market for Bioinformatics, by Solution, Through 2025
Table 30 : Global Market for Bioinformatic Tools and Database Services, by Region, Through 2025
Table 31 : Bioinformatic Tools for Pharmacogenomic Software
Table 32 : Toxicogenomic Studies Planned or Ongoing, 2016
Table 33 : Bioinformatics Archival Databases
Table 34 : Bioinformatics Curative Databases
Table 35 : Commercially Available Bioinformatics Databases
Table 36 : Biological Databases for Human Research
Table 37 : Software for Biological Analysis
Table 38 : Open-Source Bioinformatics Software
Table 39 : NGS Platforms for Clinical Diagnostics
Table 40 : Commonly Used Tools for NGS-based DNA Analysis, by Functional Category
Table 41 : Commercially Available Integrated DNA Analysis Solutions and Relevant Functionality
Table 42 : Global Market for Data Analysis Software and Analytical Services, by Region, Through 2025
Table 43 : High-Performance Computing Architectures: Advantages and Drawbacks
Table 44 : Highest Performance Supercomputers, 2018
Table 45 : SaaS Products
Table 46 : Global Market for IT Hardware and Infrastructure, by Region, Through 2025
Table 47 : Global Market for Bioinformatics, by End User, Through 2025
Table 48 : Sequencing Data Analysis Bioinformatics Software and Tools
Table 49 : Global Market for Bioinformatics for Research End Users, by Region, Through 2025
Table 50 : Global Market for Bioinformatics for Clinical and Medical End Users, by Region, Through 2025
Table 51 : Bioinformatics-Based Clinical and Medical Laboratory Information Management System
Table 52 : Tools Used to Identify the Protein Structure in Bioinformatics for Healthcare Applications and Function
Table 53 : Number of Therapeutic Drugs Developed Globally, by Disease Type, 2017
Table 54 : Global Market for Other End Users of Bioinformatics, by Region, Through 2025
Table 55 : Global Market for Bioinformatics, by Region, Through 2025
Table 56 : Number of Grants, by Type of Cancer, 2017
Table 57 : North American Market for Bioinformatics, by Solution, Through 2025
Table 58 : North American Market for Sequencing Services and Platforms, Through 2025
Table 59 : North American Market for Bioinformatics, by Application, Through 2025
Table 60 : North American Market for Bioinformatics, by End User, Through 2025
Table 61 : North American Market for Bioinformatics, by Country, Through 2025
Table 62 : Leading Bioinformatics Companies in the U.S.
Table 63 : Venture Capital Companies Most Active in the Biotech Sector, 2015
Table 64 : Estimated New Male Cancer Cases in Canada, 2017
Table 65 : Estimated New Female Cancer Cases in Canada, 2017
Table 66 : Leading Canadian Bioinformatics Companies
Table 67 : European Market for Bioinformatics, by Solution, Through 2025
Table 68 : European Market for Sequencing Services and Platforms, Through 2025
Table 69 : European Market for Bioinformatics, by Application, Through 2025
Table 70 : European Market for Bioinformatics, by End User, Through 2025
Table 71 : European Market for Bioinformatics, by Country, Through 2025
Table 72 : Leading European Bioinformatics Companies
Table 73 : Deaths Caused by Cardiovascular Disease Compared with Other Causes of Death in Germany, 2016
Table 74 : Diseases Causing the Greatest Number of Premature Deaths in Germany, Percentage Change from 2005-2016
Table 75 : Asia-Pacific Market for Bioinformatics, by Solution, Through 2025
Table 76 : Asia-Pacific Market for Sequencing Services and Platforms, Through 2025
Table 77 : Asia-Pacific Market for Bioinformatics, by Application, Through 2025
Table 78 : Asia-Pacific Market for Bioinformatics, by End User, Through 2025
Table 79 : Asia-Pacific Market for Bioinformatics, by Country, Through 2025
Table 80 : Leading Indian Bioinformatics Companies
Table 81 : Incidence of All Cancers in Australia, by Sex, 2017
Table 82 : Rest of the World Market for Bioinformatics, by Solution, Through 2025
Table 83 : Rest of the World Market for Sequencing Services and Platforms, Through 2025
Table 84 : Rest of the World Market for Bioinformatics, by Application, Through 2025
Table 85 : Rest of the World Market for Bioinformatics, by End User, Through 2025
Table 86 : Rest of the World Market for Bioinformatics, by Country, Through 2025
Table 87 : Research and Development (R&D) Spending per Capita
Table 88 : Bioinformatics Databases
Table 89 : Leading Drug Target Databases
Table 90 : Computer Simulation Platforms
Table 91 : Application of Cloud-Based Services in Healthcare
Table 92 : Leading LIMS Providers
Table 93 : Key Suppliers of ELNs
Table 94 : Leading Absorption, Distribution, Metabolism, Excretion and Toxicity Prediction Tools
Table 95 : Drug R&D Process Overview
Table 96 : Leading EHR Providers, 2018
Table 97 : Medical Applications for Healthcare Professionals
Table 98 : Pharmaceutical and Bioinformatic Partnerships and Alliances, 2015-2020
Table 99 : Agilent Technologies Inc.: Product Portfolio
Table 100 : Biomatters Ltd.: Product Portfolio
Table 101 : Bio-Rad: Product Portfolio
Table 102 : Bio-Techne: Product Portfolio
Table 103 : Compugen Ltd.: Product Portfolio
Table 104 : Dassault Systemes Biovia: Product Portfolio
Table 105 : DNASTAR Inc.: Product Portfolio
Table 106 : DNASTAR Inc.: Recent Developments, 2016
Table 107 : Genedata AG: Product Portfolio
Table 108 : Genedata AG: Recent Developments, 2017
Table 109 : Geneva Bioformatics (GeneBio) SA: Product Portfolio
Table 110 : Genomatix Software GmbH: Product Portfolio
Table 111 : GNS Healthcare Inc.: Product Portfolio
Table 112 : GNS Healthcare Inc.: Recent Developments, 2017
Table 113 : GVK Biosciences Pvt. Ltd.: Product Portfolio
Table 114 : GVK Biosciences Pvt. Ltd: Recent Developments, 2020
Table 115 : Illumina Inc.: Product Portfolio
Table 116 : Illumina Inc.: Recent Developments, 2020
Table 117 : Inte:Ligand Software Entwicklungs Und Consulting GmbH: Product Portfolio
Table 118 : MacVector Inc.: Product Portfolio
Table 119 : Molecular Connections Pvt. Ltd.: Product Portfolio
Table 120 : Molecular Networks GmbH: Product Portfolio
Table 121 : Nonlinear Dynamics Ltd.: Product Portfolio
Table 122 : Ocimum Biosolutions Ltd.: Product Portfolio
Table 123 : PerkinElmer Informatics Inc.: Product Portfolio
Table 124 : Personalis Inc.: Product Portfolio
Table 125 : Qlucore AB: Product Portfolio
Table 126 : Qlucore AB: Recent Developments, 2018
Table 127 : Real Time Genomics Inc.: Product Portfolio
Table 128 : Real Time Genomics Inc.: Recent Developments, 2016
Table 129 : Smartgene Services SARL: Product Portfolio
Table 130 : Smartgene Services SARL: Recent Developments, 2020
Table 131 : Syngene International: Product Portfolio
Table 132 : Syngene International: Recent Developments, 2019
Table 133 : Thermo Fisher Scientific: Product Portfolio
Table 134 : Acronyms Used in This Report

List of Figures

Summary Figure : Global Market Shares of Bioinformatics, by Application, 2019
Figure 1 : Bioinformatics Relationship with Omic Technologies
Figure 2 : Schematic Representation of Biology Systems and Translational Bioinformatics
Figure 3 : Principles of Precision Medicine
Figure 4 : Applications of Bioinformatics in Drug Development
Figure 5 : Collaboration within the Bioinformatics Arena, by Country, Since 2016
Figure 6 : Number of Drug Approvals, by FDA’s CDER, 2008-2020
Figure 7 : Number of CDER’s Annual Novel Drug Approvals, 2009-2019
Figure 8 : Major Socioeconomic and Political Factors Negatively Influencing the Bioinformatics Market
Figure 9 : The Four Dimensions of Big Data
Figure 10 : Software Scalability of Big Data Bioinformatics
Figure 11 : Software Validation of Big Data Bioinformatics
Figure 12 : Global Market Shares of Bioinformatics, by Application, 2019
Figure 13 : Global Market Shares of Bioinformatics, by Application, 2025
Figure 14 : Standard Antibody Sequencing Service Process
Figure 15 : Global Market for Bioinformatics in Genomics Applications, 2018-2025
Figure 16 : Global Market for Bioinformatics in Genomics Applications, by Region, 2018-2025
Figure 17 : Distribution of Breast Cancer Diagnoses among U.S. Women, by Age Group, 2017
Figure 18 : Top-Down Proteomic Approach
Figure 19 : Global Market for Bioinformatics in Proteomics Applications, 2018-2025
Figure 20 : Global Market for Bioinformatics in Proteomics Applications, by Region, 2018-2025
Figure 21 : Global Market for Bioinformatics in Transcriptomics Applications, 2018-2025
Figure 22 : Global Market for Bioinformatics in Transcriptomics Applications, by Region, 2018-2025
Figure 23 : Global Market for Bioinformatics in Metabolomics Applications, 2018-2025
Figure 24 : Global Market for Bioinformatics in Metabolomics Applications, by Region, 2018-2025
Figure 25 : Global Market for Bioinformatics in Cheminformatics Applications, 2018-2025
Figure 26 : Global Market for Bioinformatics in Cheminformatics Applications, by Region, 2018-2025
Figure 27 : Global Market for Bioinformatics in Pharmacogenomics Applications, 2018-2025
Figure 28 : Global Market for Bioinformatics in Pharmacogenomics Applications, by Region, 2018-2025
Figure 29 : Global Market for Bioinformatics in Metagenomics Applications, 2018-2025
Figure 30 : Global Market for Bioinformatics in Metagenomics Applications, by Region, 2018-2025
Figure 31 : Global Market for Bioinformatics in Other Applications, 2018-2025
Figure 32 : Global Market for Bioinformatics in Other Applications, by Region, 2018-2025
Figure 33 : Global Market Shares of Sequencing Services and Platforms, 2019
Figure 34 : Global Market Shares of Sequencing Services and Platforms, 2025
Figure 35 : Global Market for Sequencing Services, 2018-2025
Figure 36 : Global Market for Sequencing Services, by Region, 2018-2025
Figure 37 : Global Market for Sequencing Platforms, 2018-2025
Figure 38 : Global Market for Sequencing Platforms, by Region, 2018-2025
Figure 39 : Global Market Shares of Bioinformatics, by Solution, 2019
Figure 40 : Global Market Shares of Bioinformatics, by Solution, 2025
Figure 41 : Global Market for Bioinformatic Tools and Database Services, 2018-2025
Figure 42 : Global Market for Bioinformatic Tools and Database Services, by Region, 2018-2025
Figure 43 : European Bioinformatics Institute Software Solutions
Figure 44 : Global Market for Data Analysis Software and Analytical Services, 2018-2025
Figure 45 : Global Market for Data Analysis Software and Analytical Services, by Region, 2018-2025
Figure 46 : Evolution of Information Technology Infrastructure
Figure 47 : Schematic Representation of Cloud Computing Services
Figure 48 : Global Market for IT Hardware and Infrastructure, 2018-2025
Figure 49 : Global Market for IT Hardware and Infrastructure, by Region, 2018-2025
Figure 50 : Global Market Shares of Bioinformatics, by End User, 2019
Figure 51 : Global Market Shares of Bioinformatics, by End User, 2025
Figure 52 : Global Incidence of Patients with Chronic Diseases, 2005-2030
Figure 53 : Global Market for Bioinformatics for Research End Users, 2018-2025
Figure 54 : Global Market for Bioinformatics for Research End Users, by Region, 2018-2025
Figure 55 : Global Market for Bioinformatics for Clinical and Medical End Users, 2018-2025
Figure 56 : Global Market for Bioinformatics for Clinical and Medical End Users, by Region, 2018-2025
Figure 57 : Clinical Bioinformatics for Patients for Precision Health
Figure 58 : Number of Therapeutic Drugs Developed Globally, by Disease Type, 2017
Figure 59 : Global Market for Other End Users of Bioinformatics, 2018-2025
Figure 60 : Global Market for Other End Users of Bioinformatics, by Region, 2018-2025
Figure 61 : Classical and Digital Forensics with Respect to Bioinformatics
Figure 62 : Global Market Shares of Bioinformatics, by Region, 2019
Figure 63 : Global Market Shares of Bioinformatics, by Region, 2025
Figure 64 : North American Market Shares of Bioinformatics, by Solution, 2019
Figure 65 : North American Market Shares of Sequencing Services and Platforms, 2019
Figure 66 : North American Market Shares of Bioinformatics, by Application, 2019
Figure 67 : North American Market Shares of Bioinformatics, by End User, 2019
Figure 68 : North American Market Shares of Bioinformatics, by Country, 2019
Figure 69 : U.S. Market for Bioinformatics, 2018-2025
Figure 70 : Canadian Market for Bioinformatics, 2018-2025
Figure 71 : Mexican Market for Bioinformatics, 2018-2025
Figure 72 : European Market Shares of Bioinformatics, by Solution, 2019
Figure 73 : European Market Shares of Sequencing Services and Platforms, 2019
Figure 74 : European Market Shares of Bioinformatics, by Application, 2019
Figure 75 : European Market Shares of Bioinformatics, by End User, 2019
Figure 76 : European Market Shares of Bioinformatics, by Country, 2019
Figure 77 : German Market for Bioinformatics, 2018-2025
Figure 78 : Current Molecular-Experimental, Epidemiological and Analytical Tools Applied in Systems Medicine
Figure 79 : French Market for Bioinformatics, 2018-2025
Figure 80 : Health Spending and Financing in France, 2005-2018
Figure 81 : Market Demand for Medical Equipment in France, 2015-2017
Figure 82 : U.K. Market for Bioinformatics, 2018-2025
Figure 83 : Italian Market for Bioinformatics, 2018-2025
Figure 84 : Spanish Market for Bioinformatics, 2018-2025
Figure 85 : Rest of the European Market for Bioinformatics, 2018-2025
Figure 86 : Asia-Pacific Market Shares of Bioinformatics, by Solution, 2019
Figure 87 : Asia-Pacific Market Shares of Sequencing Services and Platforms, 2019
Figure 88 : Asia-Pacific Market Shares of Bioinformatics, by Application, 2019
Figure 89 : Asia-Pacific Market Shares of Bioinformatics, by End User, 2019
Figure 90 : Asia-Pacific Market Shares of Bioinformatics, by Country, 2019
Figure 91 : Japanese Market for Bioinformatics, 2018-2025
Figure 92 : Chinese Market for Bioinformatics, 2018-2025
Figure 93 : Indian Market for Bioinformatics, 2018-2025
Figure 94 : Key Areas of Research Utilizing Bioinformatics
Figure 95 : Australian and New Zealand Market for Bioinformatics, 2018-2025
Figure 96 : Rest of Asia-Pacific Market for Bioinformatics, 2018-2025
Figure 97 : Rest of the World Market Shares of Bioinformatics, by Solution, 2019
Figure 98 : Rest of the World Market Shares of Sequencing Services and Platforms, 2019
Figure 99 : Rest of the World Market Shares of Bioinformatics, by Application, 2019
Figure 100 : Rest of the World Market Shares of Bioinformatics, by End User, 2019
Figure 101 : Rest of the World Market Shares of Bioinformatics, by Country, 2019
Figure 102 : Brazilian Market for Bioinformatics, 2018-2025
Figure 103 : GCC Countries Market for Bioinformatics, 2018-2025
Figure 104 : Bioinformatics Market in the Other Rest of the World Countries, 2018-2025
Figure 105 : Number of Research Articles per Country Published, by Scientists from 19 Countries on Bioinformatics and Computational Biology, 1991-2016
Figure 106 : Policy, Infrastructure, Training and Funding Landscape of Computational Biology in South Africa, 2000-Present
Figure 107 : Impact of COVID-19 on the Pharmaceutical/Biotech Industry
Figure 108 : Drug Development Process
Figure 109 : Phases in the Drug Discovery and Development Process
Figure 110 : Phase Transition Success Rates and Likelihood of Approvals for All Modalities and Medicines, 2017
Figure 111 : Steps in Drug Discovery
Figure 112 : Information Systems within the Laboratory Architecture
Figure 113 : Application of Bioinformatics in Clinical Trials
Figure 114 : Global Market Ranking of Bioinformatics, by Manufacturer, 2019
Figure 115 : Agilent Technologies Inc.: Annual Revenue, 2016-2020
Figure 116 : Agilent Technologies Inc.: Revenue Shares, by Region, 2019
Figure 117 : Agilent Technologies Inc.: Revenue Shares, by Business Segment, 2020
Figure 118 : Bio-Rad: Annual Revenue, 2016-2019
Figure 119 : Bio-Rad: Revenue Shares, by Region/Country, 2019
Figure 120 : Bio-Rad: Revenue Shares, by Business Unit, 2019
Figure 121 : Bio-Techne: Annual Revenue, 2016-2019
Figure 122 : Bio-Techne: Revenue Shares, by Region/Country, 2019
Figure 123 : Bio-Techne: Revenue Shares, by Business Segment, 2019
Figure 124 : Illumina Inc.: Annual Revenue, 2018-2020
Figure 125 : Illumina Inc.: Revenue Shares, by Region, 2020
Figure 126 : Illumina Inc.: Revenue Shares, by Business Segment, 2020
Figure 127 : Thermo Fisher Scientific: Annual Revenue, 2016-2019
Figure 128 : Thermo Fisher Scientific: Revenue Shares, by Region, 2019
Figure 129 : Thermo Fisher Scientific: Revenue Shares, by Business Segment, 2019

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