In Vitro Toxicology Testing Market by Products (Assays) & Services, Toxicity Endpoints & Tests (ADME, Skin, Genotoxicity, Organ Toxicity), Technology (Cell-based, HTS), Method (Cellular Assays, Ex-Vivo), Industry (Pharmaceutical, Cosmetics) - Forecast to 2022

Table of Contents

1 INTRODUCTION 17

1.1 OBJECTIVES OF THE STUDY 17
1.2 MARKET DEFINITION 17
1.3 MARKET SCOPE 18
1.3.1 MARKETS COVERED 18
1.3.2 YEARS COVERED FOR THE STUDY 18
1.4 CURRENCY 19
1.5 LIMITATIONS 19
1.6 STAKEHOLDERS 19

2 RESEARCH METHODOLOGY 20

2.1 RESEARCH DATA 20
2.2 MARKET SHARE ESTIMATION 22
2.2.1 SECONDARY DATA 22
2.2.1.1 Key data from secondary sources 22
2.2.2 PRIMARY DATA 23
2.2.2.1 Key data from primary sources 23
2.2.2.2 Key industry insights 24
2.3 MARKET SIZE ESTIMATION 25
2.4 MARKET BREAKDOWN AND DATA TRIANGULATION 27
2.5 ASSUMPTIONS FOR THE STUDY 28

3 EXECUTIVE SUMMARY 29
4 PREMIUM INSIGHTS 35

4.1 GLOBAL IN VITRO TOXICOLOGY TESTING MARKET OVERVIEW 35
4.2 EUROPE IN VITRO TOXICOLOGY TESTING MARKET: BY TECHNOLOGY & COUNTRY 36
4.3 IN VITRO TOXICOLOGY TESTING MARKET: BY COUNTRY/REGION 37
4.4 IN VITRO TOXICOLOGY TESTING MARKET: GEOGRAPHIC MIX 38
4.5 IN VITRO TOXICOLOGY TESTING MARKET: DEVELOPING VS. DEVELOPED MARKETS
(USD BILLION) 39

5 INDUSTRY INSIGHTS 40

5.1 INTRODUCTION 40
5.2 SUPPLY CHAIN ANALYSIS 40
5.3 REGULATORY COMMITTEE ACTIVITIES 41
5.3.1 MAJOR STAKEHOLDERS 42
5.3.2 KEY INFLUENCERS 42
5.4 INDUSTRY TRENDS 43
5.4.1 INCREASING R&D SPENDING IN THE PHARMACEUTICAL AND BIOTECHNOLOGY SECTOR 43
5.4.2 NEW AND PROMISING TECHNOLOGICAL ADVANCEMENTS A KEY AREA OF FOCUS FOR MARKET PLAYERS 44

6 MARKET OVERVIEW 45

6.1 INTRODUCTION 45
6.2 MARKET DYNAMICS 46
6.2.1 DRIVERS 47
6.2.1.1 Opposition to animal testing 47
6.2.1.2 New and promising in vitro technologies 48
6.2.1.3 Increasing R&D expenditure to detect toxicity at an early stage 48
6.2.2 RESTRAINTS 49
6.2.2.1 Reluctance of regulatory authorities to consider alternative methods for proving safety and efficacy 49
6.2.2.2 Failure to establish intricacies of in vivo conditions through in vitro 49
6.2.2.3 Lack of in vitro models to study complex endpoints 49
6.2.3 OPPORTUNITIES 50
6.2.3.1 Toxicology in the 21st century (Tox21) program 50
6.2.3.2 Increasing drug discovery and innovation & modernization in the in vitro toxicity testing market 50
6.2.3.3 Increasing toxicology databases will facilitate the use of in vitro test methods 51
6.2.4 CHALLENGES 51
6.2.4.1 Dearth of skilled professionals 51

7 IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT AND SERVICE 52

7.1 INTRODUCTION 53
7.2 ASSAYS 54
7.2.1 BACTERIAL TOXICITY ASSAYS 56
7.2.2 ENZYME TOXICITY ASSAYS 58
7.2.3 CELL-BASED ELISA AND WESTERN BLOTS 60
7.2.4 RECEPTOR-BINDING ASSAYS 62
7.2.5 TISSUE CULTURE ASSAYS 63
7.2.6 OTHER ASSAYS 65
7.3 SERVICES 67
7.4 REAGENTS & LABWARE 69

8 IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICITY ENDPOINTS AND TESTS 71

8.1 INTRODUCTION 72
8.1.1 ADME (ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION) 73
8.1.2 SKIN IRRITATION, CORROSION, AND SENSITIZATION 75
8.1.3 GENOTOXICITY TESTING 77
8.1.4 CYTOTOXICITY TESTING 79
8.1.5 OCULAR TOXICITY 81
8.1.6 ORGAN TOXICITY 83
8.1.7 PHOTOTOXICITY TESTING 84
8.1.8 DERMAL TOXICITY 86
8.1.9 CARCINOGENICITY 88
8.1.10 NEUROTOXICITY 89
8.1.11 OTHER TOXICITY ENDPOINTS & TESTS 91

9 IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY 93

9.1 INTRODUCTION 94
9.2 CELL CULTURE TECHNOLOGIES 95
9.3 HIGH-THROUGHPUT TECHNOLOGIES 97
9.4 CELLULAR IMAGING TECHNOLOGIES 99
9.5 TOXICOGENOMICS 101

10 IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY 103

10.1 INTRODUCTION 104
10.2 PHARMACEUTICAL AND BIOPHARMACEUTICAL INDUSTRY 105
10.3 COSMETICS AND HOUSEHOLD PRODUCTS INDUSTRY 107
10.4 FOOD INDUSTRY 109
10.5 CHEMICAL INDUSTRY 111

11 IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD 113

11.1 INTRODUCTION 114
11.2 CELLULAR ASSAYS 114
11.3 BIOCHEMICAL ASSAYS 116
11.4 EX VIVO MODELS 117

12 IN VITRO TOXICOLOGY TESTING MARKET, BY REGION 118

12.1 INTRODUCTION 119
12.2 EUROPE 121
12.2.1 GERMANY 126
12.2.2 UK 130
12.2.3 FRANCE 135
12.2.4 ITALY 139
12.2.5 SPAIN 142
12.2.6 REST OF EUROPE (ROE) 146
12.3 NORTH AMERICA 150
12.3.1 US 154
12.3.2 CANADA 158
12.4 ASIA PACIFIC 162
12.4.1 JAPAN 167
12.4.2 CHINA 171
12.4.3 INDIA 175
12.4.4 REST OF ASIA PACIFIC (ROAPAC) 178
12.5 REST OF THE WORLD (ROW) 183

13 COMPETITIVE LANDSCAPE 187

13.1 OVERVIEW 187
13.2 MARKET RANKING ANALYSIS 187

14 COMPANY PROFILES 188

(Overview, Products and Services, Financials, Strategy & Development)*
14.1 SGS S.A. 188
14.2 COVANCE, INC. (A PART OF LABORATORY CORPORATION OF AMERICA HOLDINGS) 193
14.3 BIO-RAD LABORATORIES, INC. 197
14.4 QIAGEN N.V. 201
14.5 GE HEALTHCARE 205
14.6 EUROFINS SCIENTIFIC SE 208
14.7 MERCK KGAA 214
14.8 THERMO FISHER SCIENTIFIC, INC 218
14.9 CHARLES RIVER LABORATORIES INTERNATIONAL, INC. 223
14.10 CATALENT, INC. 226
14.11 CYPROTEX PLC (A SUBSIDIARY OF EVOTEC AG) 229
14.12 PROMEGA CORPORATION 234
14.13 GENTRONIX LIMITED 237
14.14 ASCENDANCE BIOTECHNOLOGY, INC. 239
14.15 MB RESEARCH LABORATORIES 242

*Details on Overview, Products and Services, Financials, Strategy & Development might not be Captured in case of Unlisted Companies.
15 APPENDIX 244

LIST OF TABLES

TABLE 1 IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT AND SERVICE,
2015–2022 (USD MILLION) 53
TABLE 2 IN VITRO TOXICOLOGY TESTING MARKET FOR ASSAYS, BY TYPE,
2015–2022 (USD MILLION) 54
TABLE 3 IN VITRO TOXICOLOGY TESTING MARKET FOR ASSAYS, BY COUNTRY/REGION, 2015–2022 (USD MILLION) 55
TABLE 4 IN VITRO TOXICOLOGY TESTING MARKET FOR BACTERIAL TOXICITY ASSAYS,
BY COUNTRY/REGION, 2015–2022 (USD MILLION) 57
TABLE 5 IN VITRO TOXICITY TESTING MARKET FOR ENZYME TOXICITY ASSAYS,
BY COUNTRY/REGION, 2015–2022 (USD MILLION) 59
TABLE 6 IN VITRO TOXICOLOGY TESTING MARKET FOR CELL-BASED ELISA AND WESTERN BLOTS, BY COUNTRY/REGION, 2015–2022 (USD MILLION) 61
TABLE 7 IN VITRO TOXICOLOGY TESTING MARKET FOR RECEPTOR-BINDING ASSAYS,
BY COUNTRY/REGION, 2015–2022 (USD MILLION) 62
TABLE 8 IN VITRO TOXICOLOGY TESTING MARKET FOR TISSUE CULTURE ASSAYS,
BY COUNTRY/REGION, 2015–2022 (USD MILLION) 64
TABLE 9 IN VITRO TOXICOLOGY TESTING MARKET FOR OTHER ASSAYS,
BY COUNTRY/REGION, 2015–2022 (USD MILLION) 66
TABLE 10 IN VITRO TOXICOLOGY TESTING MARKET FOR SERVICES, BY COUNTRY/REGION, 2015–2022 (USD MILLION) 68
TABLE 11 IN VITRO TOXICOLOGY TESTING MARKET FOR REAGENTS & LABWARE,
BY COUNTRY/REGION, 2015–2022 (USD MILLION) 70
TABLE 12 IN VITRO TOXICITY TESTING MARKET, BY TOXICITY ENDPOINT AND TEST,
2015–2022 (USD MILLION) 72
TABLE 13 IN VITRO TOXICITY TESTING MARKET FOR ADME, BY COUNTRY/REGION,
2015–2022 (USD MILLION) 74
TABLE 14 IN VITRO TOXICITY TESTING MARKET FOR SKIN IRRITATION, CORROSION, AND SENSITIZATION, BY COUNTRY/REGION, 2015–2022 (USD MILLION) 76
TABLE 15 IN VITRO TOXICITY TESTING MARKET FOR GENOTOXICITY TESTING,
BY COUNTRY/REGION, 2015–2022 (USD MILLION) 78
TABLE 16 IN VITRO TOXICITY TESTING MARKET FOR CYTOTOXICITY TESTING,
BY COUNTRY/REGION, 2015–2022 (USD MILLION) 80
TABLE 17 IN VITRO TOXICITY TESTING MARKET FOR OCULAR TOXICITY,
BY COUNTRY/REGION, 2015–2022 (USD MILLION) 82
TABLE 18 IN VITRO TOXICITY TESTING MARKET FOR ORGAN TOXICITY, BY COUNTRY/REGION, 2015–2022 (USD MILLION) 83
TABLE 19 IN VITRO TOXICITY TESTING MARKET FOR PHOTOTOXICITY TESTING,
BY COUNTRY/REGION, 2015–2022 (USD MILLION) 85
TABLE 20 IN VITRO TOXICITY TESTING MARKET FOR DERMAL TOXICITY,
BY COUNTRY/REGION, 2015–2022 (USD MILLION) 87
TABLE 21 IN VITRO TOXICITY TESTING MARKET FOR CARCINOGENICITY,
BY COUNTRY/REGION, 2015–2022 (USD MILLION) 88
TABLE 22 IN VITRO TOXICITY TESTING MARKET FOR NEUROTOXICITY, BY COUNTRY/REGION, 2015–2022 (USD MILLION) 90
TABLE 23 IN VITRO TOXICITY TESTING MARKET FOR OTHER TOXICITY ENDPOINT & TEST,
BY COUNTRY/REGION, 2015–2022 (USD MILLION) 92
TABLE 24 IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY,
2015–2022 (USD MILLION) 94
TABLE 25 IN VITRO TOXICOLOGY TESTING MARKET FOR CELL CULTURE TECHNOLOGIES,
BY COUNTRY/REGION, 2015–2022 (USD MILLION) 96
TABLE 26 IN VITRO TOXICOLOGY TESTING MARKET FOR HIGH-THROUGHPUT TECHNOLOGIES, BY COUNTRY/REGION, 2015–2022 (USD MILLION) 98
TABLE 27 IN VITRO TOXICOLOGY TESTING MARKET FOR CELLULAR IMAGING TECHNOLOGIES, BY COUNTRY/REGION, 2015–2022 (USD MILLION) 100
TABLE 28 IN VITRO TOXICOLOGY TESTING MARKET FOR TOXICOGENOMICS,
BY COUNTRY/REGION, 2015–2022 (USD MILLION) 102
TABLE 29 IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY,
2015–2022 (USD MILLION) 104
TABLE 30 IN VITRO TOXICOLOGY TESTING MARKET FOR PHARMACEUTICALS AND BIOPHARMACEUTICALS INDUSTRY, BY COUNTRY/REGION,
2015–2022 (USD MILLION) 106
TABLE 31 IN VITRO TOXICOLOGY TESTING MARKET FOR COSMETICS & HOUSEHOLD PRODUCTS INDUSTRY, BY COUNTRY/REGION, 2015–2022 (USD MILLION) 108
TABLE 32 IN VITRO TOXICOLOGY TESTING MARKET FOR THE FOOD INDUSTRY,
BY COUNTRY/REGION, 2015–2022 (USD MILLION) 110
TABLE 33 IN VITRO TOXICOLOGY TESTING MARKET SIZE FOR THE CHEMICAL INDUSTRY,
BY COUNTRY/REGION, 2015–2022 (USD MILLION) 112
TABLE 34 IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD, 2015–2022 (USD MILLION) 114
TABLE 35 IN VITRO TOXICOLOGY TESTING MARKET FOR CELLULAR ASSAYS,
BY COUNTRY/REGION, 2015–2022 (USD MILLION) 115
TABLE 36 IN VITRO TOXICOLOGY TESTING MARKET FOR BIOCHEMICAL ASSAYS,
BY COUNTRY/REGION, 2015–2022 (USD MILLION) 116
TABLE 37 IN VITRO TOXICOLOGY TESTING MARKET FOR EX VIVO ASSAYS,
BY COUNTRY/REGION, 2015–2022 (USD MILLION) 117
TABLE 38 IN VITRO TOXICOLOGY TESTING MARKET, BY REGION, 2015–2022 (USD MILLION) 120
TABLE 39 IN VITRO TOXICOLOGY TESTING MARKET, BY COUNTRY/REGION,
2015–2022 (USD MILLION) 120
TABLE 40 EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY COUNTRY/REGION,
2015–2022 (USD MILLION) 123
TABLE 41 EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT AND SERVICE, 2015–2022(USD MILLION) 123
TABLE 42 EUROPE: IN VITRO TOXICOLOGY TESTING MARKET FOR ASSAYS, BY TYPE,
2015–2022 (USD MILLION) 124
TABLE 43 EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICITY ENDPOINT & TEST, 2015–2022 (USD MILLION) 124
TABLE 44 EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY,
2015–2022 (USD MILLION) 125
TABLE 45 EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD,
2015–2022 (USD MILLION) 125
TABLE 46 EUROPE: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY,
2015–2022 (USD MILLION) 126
TABLE 47 GERMANY: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT AND SERVICE, 2015–2022(USD MILLION) 127
TABLE 48 GERMANY: IN VITRO TOXICOLOGY TESTING MARKET FOR ASSAYS, BY TYPE,
2015–2022 (USD MILLION) 128
TABLE 49 GERMANY: IN VITRO TOXICOLOGY TESTING MARKET,
BY TOXICITY ENDPOINT & TEST, 2015–2022 (USD MILLION) 128
TABLE 50 GERMANY: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY,
2015–2022 (USD MILLION) 129
TABLE 51 GERMANY: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD,
2015–2022 (USD MILLION) 129
TABLE 52 GERMANY: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY,
2015–2022 (USD MILLION) 130
TABLE 53 UK: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT AND SERVICE,
2015–2022(USD MILLION) 132
TABLE 54 UK: IN VITRO TOXICOLOGY TESTING MARKET FOR ASSAYS, BY TYPE,
2015–2022 (USD MILLION) 132
TABLE 55 UK: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICITY ENDPOINT & TEST, 2015–2022 (USD MILLION) 133
TABLE 56 UK: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY,
2015–2022 (USD MILLION) 133
TABLE 57 UK: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD,
2015–2022 (USD MILLION) 134
TABLE 58 UK: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY,
2015–2022 (USD MILLION) 134
TABLE 59 FRANCE: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT AND SERVICE, 2015–2022 (USD MILLION) 136
TABLE 60 FRANCE: IN VITRO TOXICOLOGY TESTING MARKET FOR ASSAYS, BY TYPE,
2015–2022 (USD MILLION) 136
TABLE 61 FRANCE: IN VITRO TOXICOLOGY TESTING MARKET,
BY TOXICITY ENDPOINT & TESTS, 2015–2022 (USD MILLION) 137
TABLE 62 FRANCE: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY,
2015–2022 (USD MILLION) 137
TABLE 63 FRANCE: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD,
2015–2022 (USD MILLION) 138
TABLE 64 FRANCE: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY,
2015–2022 (USD MILLION) 138
TABLE 65 ITALY: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT AND SERVICE, 2015–2022 (USD MILLION) 139
TABLE 66 ITALY: IN VITRO TOXICOLOGY TESTING MARKET FOR ASSAYS, BY TYPE,
2015–2022 (USD MILLION) 140
TABLE 67 ITALY: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICITY ENDPOINT & TEST, 2015–2022 (USD MILLION) 140
TABLE 68 ITALY: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY,
2015–2022 (USD MILLION) 141
TABLE 69 ITALY: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD,
2015–2022 (USD MILLION) 141
TABLE 70 ITALY: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY,
2015–2022 (USD MILLION) 142
TABLE 71 SPAIN: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT AND SERVICE, 2015–2022(USD MILLION) 143
TABLE 72 SPAIN: IN VITRO TOXICOLOGY TESTING MARKET FOR ASSAYS, BY TYPE,
2015–2022 (USD MILLION) 143
TABLE 73 SPAIN: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICITY ENDPOINT & TESTS, 2015–2022 (USD MILLION) 144
TABLE 74 SPAIN: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY,
2015–2022 (USD MILLION) 144
TABLE 75 SPAIN: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD,
2015–2022 (USD MILLION) 145
TABLE 76 SPAIN: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY,
2015–2022 (USD MILLION) 145
TABLE 77 ROE: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT AND SERVICE,
2015–2022(USD MILLION) 147
TABLE 78 ROE: IN VITRO TOXICOLOGY TESTING MARKET FOR ASSAYS, BY TYPE,
2015–2022 (USD MILLION) 148
TABLE 79 ROE: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICITY ENDPOINT & TEST, 2015–2022 (USD MILLION) 148
TABLE 80 ROE: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY,
2015–2022 (USD MILLION) 149
TABLE 81 ROE: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD,
2015–2022 (USD MILLION) 149
TABLE 82 ROE: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY,
2015–2022 (USD MILLION) 150
TABLE 83 NORTH AMERICA: IN VITRO TOXICOLOGY TESTING MARKET, BY COUNTRY/REGION, 2015–2022 (USD MILLION) 151
TABLE 84 NORTH AMERICA: IN VITRO TOXICOLOGY TESTING MARKET,
BY PRODUCT AND SERVICE, 2015–2022(USD MILLION) 151
TABLE 85 NORTH AMERICA: IN VITRO TOXICOLOGY TESTING MARKET FOR ASSAYS, BY TYPE, 2015–2022 (USD MILLION) 152
TABLE 86 NORTH AMERICA: IN VITRO TOXICOLOGY TESTING MARKET,
BY TOXICITY ENDPOINT & TEST, 2015–2022 (USD MILLION) 152
TABLE 87 NORTH AMERICA: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY, 2015–2022 (USD MILLION) 153
TABLE 88 NORTH AMERICA: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD,
2015–2022 (USD MILLION) 153
TABLE 89 NORTH AMERICA: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY,
2015–2022 (USD MILLION) 154
TABLE 90 US: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT AND SERVICE,
2015–2022(USD MILLION) 155
TABLE 91 US: IN VITRO TOXICOLOGY TESTING MARKET FOR ASSAYS, BY TYPE,
2015–2022 (USD MILLION) 156
TABLE 92 US: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICITY ENDPOINT & TEST, 2015–2022 (USD MILLION) 156
TABLE 93 US: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY,
2015–2022 (USD MILLION) 157
TABLE 94 US: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD,
2015–2022 (USD MILLION) 157
TABLE 95 US: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY,
2015–2022 (USD MILLION) 158
TABLE 96 CANADA: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT AND SERVICE, 2015–2022(USD MILLION) 159
TABLE 97 CANADA: IN VITRO TOXICOLOGY TESTING MARKET FOR ASSAYS, BY TYPE,
2015–2022 (USD MILLION) 159
TABLE 98 CANADA: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICITY ENDPOINT & TEST, 2015–2022 (USD MILLION) 160
TABLE 99 CANADA: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY,
2015–2022 (USD MILLION) 160
TABLE 100 CANADA: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD,
2015–2022 (USD MILLION) 161
TABLE 101 CANADA: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY,
2015–2022 (USD MILLION) 161
TABLE 102 APAC: IN VITRO TOXICOLOGY TESTING MARKET, BY COUNTRY/REGION,
2015–2022 (USD MILLION) 164
TABLE 103 APAC: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT AND SERVICE, 2015–2022(USD MILLION) 164
TABLE 104 APAC: IN VITRO TOXICOLOGY TESTING MARKET FOR ASSAYS, BY TYPE,
2015–2022 (USD MILLION) 165
TABLE 105 APAC: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICITY ENDPOINT & TEST, 2015–2022 (USD MILLION) 165
TABLE 106 APAC: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY,
2015–2022 (USD MILLION) 166
TABLE 107 APAC: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD,
2015–2022 (USD MILLION) 166
TABLE 108 APAC: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY,
2015–2022 (USD MILLION) 167
TABLE 109 JAPAN: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT AND SERVICE, 2015–2022(USD MILLION) 168
TABLE 110 JAPAN: IN VITRO TOXICOLOGY TESTING MARKET FOR ASSAYS, BY TYPE,
2015–2022 (USD MILLION) 169
TABLE 111 JAPAN: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICITY ENDPOINT & TESTS, 2015–2022 (USD MILLION) 169
TABLE 112 JAPAN: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY,
2015–2022 (USD MILLION) 170
TABLE 113 JAPAN: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD,
2015–2022 (USD MILLION) 170
TABLE 114 JAPAN: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY,
2015–2022 (USD MILLION) 171
TABLE 115 CHINA: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT AND SERVICE, 2015–2022(USD MILLION) 172
TABLE 116 CHINA: IN VITRO TOXICOLOGY TESTING MARKET FOR ASSAYS, BY TYPE,
2015–2022 (USD MILLION) 172
TABLE 117 CHINA: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICITY ENDPOINT & TEST, 2015–2022 (USD MILLION) 173
TABLE 118 CHINA: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY,
2015–2022 (USD MILLION) 173
TABLE 119 CHINA: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD,
2015–2022 (USD MILLION) 174
TABLE 120 CHINA: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY,
2015–2022 (USD MILLION) 174
TABLE 121 INDIA: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT AND SERVICE, 2015–2022(USD MILLION) 175
TABLE 122 INDIA: IN VITRO TOXICOLOGY TESTING MARKET FOR ASSAYS, BY TYPE,
2015–2022 (USD MILLION) 176
TABLE 123 INDIA: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICITY ENDPOINT & TEST, 2015–2022 (USD MILLION) 176
TABLE 124 INDIA: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY,
2015–2022 (USD MILLION) 177
TABLE 125 INDIA: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD,
2015–2022 (USD MILLION) 177
TABLE 126 INDIA: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY,
2015–2022 (USD MILLION) 178
TABLE 127 ROAPAC: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT AND SERVICE, 2015–2022(USD MILLION) 180
TABLE 128 ROAPAC: IN VITRO TOXICOLOGY TESTING MARKET FOR ASSAYS, BY TYPE,
2015–2022 (USD MILLION) 180
TABLE 129 ROAPAC: IN VITRO TOXICOLOGY TESTING MARKET,
BY TOXICITY ENDPOINT & TESTS, 2015–2022 (USD MILLION) 181
TABLE 130 ROAPAC: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY,
2015–2022 (USD MILLION) 181
TABLE 131 ROAPAC: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD,
2015–2022 (USD MILLION) 182
TABLE 132 ROAPAC: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY,
2015–2022 (USD MILLION) 182
TABLE 133 ROW: IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT AND SERVICE,
2015–2022(USD MILLION) 184
TABLE 134 ROW: IN VITRO TOXICOLOGY TESTING MARKET FOR ASSAYS, BY TYPE,
2015–2022 (USD MILLION) 184
TABLE 135 ROW: IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICITY ENDPOINT & TEST, 2015–2022 (USD MILLION) 185
TABLE 136 ROW: IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY,
2015–2022 (USD MILLION) 185
TABLE 137 ROW: IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD,
2015–2022 (USD MILLION) 186
TABLE 138 ROW: IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY,
2015–2022 (USD MILLION) 186
TABLE 139 RANK OF COMPANIES IN THE IN VITRO TOXICOLOGY TESTING MARKET, 2016 187

LIST OF FIGURES

FIGURE 1 RESEARCH DESIGN 20
FIGURE 2 BREAKDOWN OF PRIMARY INTERVIEWS: BY COMPANY TYPE,
DESIGNATION, AND REGION 24
FIGURE 3 MARKET SIZE ESTIMATION METHODOLOGY: BOTTOM-UP APPROACH 25
FIGURE 4 MARKET SIZE ESTIMATION METHODOLOGY: TOP-DOWN APPROACH 26
FIGURE 5 DATA TRIANGULATION METHODOLOGY 27
FIGURE 6 IN VITRO TOXICOLOGY TESTING MARKET, BY PRODUCT AND SERVICE,
2017 VS. 2022 (USD BILLION) 29
FIGURE 7 IN VITRO TOXICOLOGY TESTING MARKET, BY TOXICITY ENDPOINT & TEST,
2017 VS. 2022 (USD MILLION) 30
FIGURE 8 IN VITRO TOXICOLOGY TESTING MARKET, BY TECHNOLOGY,
2017 VS. 2022 (USD BILLION) 31
FIGURE 9 IN VITRO TOXICOLOGY TESTING MARKET, BY METHOD,
2017 VS. 2022 (USD BILLION) 32
FIGURE 10 IN VITRO TOXICOLOGY TESTING MARKET, BY INDUSTRY,
2017 VS. 2022 (USD BILLION) 33
FIGURE 11 GEOGRAPHICAL SNAPSHOT OF THE IN VITRO TOXICOLOGY TESTING MARKET, 2017 34
FIGURE 12 OPPOSITION TO ANIMAL TESTING AND INCREASE IN R&D SPENDING TO DRIVE MARKET GROWTH 35
FIGURE 13 TOXICOGENOMICS TECHNOLOGIES IS EXPECTED TO COMMAND THE LARGEST MARKET SHARE IN 2017 36
FIGURE 14 CHINA TO REGISTER HIGHEST GROWTH DURING THE FORECAST PERIOD 37
FIGURE 15 EUROPE HOLDS THE HIGHEST MARKET SHARE DURING THE FORECAST PERIOD 38
FIGURE 16 DEVELOPING MARKETS TO GROW AT THE HIGHEST CAGRS FROM 2017 TO 2022 39
FIGURE 17 SUPPLY CHAIN ANALYSIS: IN VITRO TOXICOLOGY TESTING MARKET (AS OF 2016) 40
FIGURE 18 IN VITRO TOXICOLOGY TESTING MARKET: DRIVERS, RESTRAINTS, OPPORTUNITIES, AND CHALLENGES 46
FIGURE 19 GLOBAL IN VITRO TOXICOLOGY TESTING MARKET SNAPSHOT (2017) 119
FIGURE 20 EUROPE: IN VITRO TOXICOLOGY TESTING MARKET SNAPSHOT,
2017 (USD MILLION) 122
FIGURE 21 ASIA PACIFIC: IN VITRO TOXICOLOGY TESTING MARKET SNAPSHOT (2017) 163
FIGURE 22 SGS S.A.: COMPANY SNAPSHOT (2016) 188
FIGURE 23 LABORATORY CORPORATION OF AMERICA HOLDINGS:
COMPANY SNAPSHOT (2016) 193
FIGURE 24 BIO-RAD LABORATORIES, INC.: COMPANY SNAPSHOT (2016) 197
FIGURE 25 QIAGEN N.V.: COMPANY SNAPSHOT (2016) 201
FIGURE 26 GE HEALTHCARE: COMPANY SNAPSHOT (2016) 205
FIGURE 27 EUROFINS SCIENTIFIC SE: COMPANY SNAPSHOT (2016) 208
FIGURE 28 MERCK KGAA: COMPANY SNAPSHOT (2016) 214
FIGURE 29 THERMO FISHER SCIENTIFIC, INC.: COMPANY SNAPSHOT (2016) 218
FIGURE 30 CHARLES RIVER LABORATORIES INTERNATIONAL, INC.:
COMPANY SNAPSHOT (2016) 223
FIGURE 31 CATALENT, INC.: COMPANY SNAPSHOT (2016) 226
FIGURE 32 EVOTEC AG: COMPANY SNAPSHOT (2016) 229

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