Extracorporeal Membrane Oxygenation Machine Market by Modality (Veno-Arterial (VA), Veno-Venous (VV), Arterio-Venous (AV)), Application (Respiratory, Cardiac, Extracorporeal Cardiopulmonary Resuscitation (ECPR)), and Region - Analysis & Forecasts to 2021

Table of Contents

1 INTRODUCTION 14

1.1 OBJECTIVES OF THE STUDY 14
1.2 MARKET DEFINITION 14
1.3 MARKET SCOPE 15
1.3.1 MARKETS COVERED 15
1.3.2 YEARS CONSIDERED FOR THE STUDY 16
1.4 CURRENCY 16
1.5 LIMITATIONS 16
1.6 STAKEHOLDERS 16

2 RESEARCH METHODOLOGY 17

2.1 RESEARCH METHODOLOGY STEPS 17
2.2 SECONDARY AND PRIMARY RESEARCH METHODOLOGY 18
2.2.1 SECONDARY RESEARCH 18
2.2.1.1 Key data from secondary sources 18
2.2.2 PRIMARY RESEARCH 20
2.2.2.1 Key data from primary sources 20
2.2.2.2 Key insights from primary sources 21
2.2.2.3 Key industry insights 22
2.3 MARKET SIZE ESTIMATION METHODOLOGY 23
2.4 MARKET DATA VALIDATION AND TRIANGULATION 26
2.5 ASSUMPTIONS FOR THE STUDY 27

3 EXECUTIVE SUMMARY 28

3.1 INTRODUCTION 28
3.2 CONCLUSION 31

4 PREMIUM INSIGHTS 32

4.1 EXTRACORPOREAL MEMBRANE OXYGENATION (ECMO) MACHINE: MARKET OVERVIEW 32
4.2 GEOGRAPHIC ANALYSIS: ECMO MACHINE MARKET, BY MODALITY (2016) 33
4.3 ECMO MACHINE MARKET, BY APPLICATION, 2016 VS. 2021 34
4.4 GEOGRAPHIC SNAPSHOT OF THE ECMO MACHINE MARKET 34

5 MARKET OVERVIEW 35

5.1 INTRODUCTION 36
5.2 MARKET DYNAMICS 36
5.2.1 DRIVERS 37
5.2.1.1 Increasing prevalence of cardiovascular and respiratory diseases 37
5.2.1.2 Growing adoption of ECMO in lung transplantation procedures 38
5.2.1.3 Growth in the number of ECMO centers 38
5.2.1.4 Technological advancements in ECMO machine 39
5.2.2 RESTRAINTS 39
5.2.2.1 Complications associated with ECMO 39
5.2.2.2 High cost of ECMO procedures 40
5.2.3 OPPORTUNITIES 40
5.2.3.1 Increasing survival rates with ECMO 40
5.2.4 CHALLENGES 41
5.2.4.1 Lack of skilled professionals 41

6 GLOBAL EXTRACORPOREAL MEMBRANE OXYGENATION MACHINE MARKET, BY MODALITY 42

6.1 INTRODUCTION 43
6.2 VENOVENOUS ECMO 43
6.3 VENOARTERIAL ECMO 45
6.4 ARTERIOVENOUS ECMO 47

7 GLOBAL EXTRACORPOREAL MEMBRANE OXYGENATION MACHINE MARKET, BY APPLICATION 49

7.1 INTRODUCTION 50
7.2 RESPIRATORY APPLICATIONS 51
7.2.1 NEONATES 53
7.2.2 PEDIATRICS 53
7.2.3 ADULTS 54
7.3 CARDIAC APPLICATIONS 55
7.3.1 ADULTS 57
7.3.2 PEDIATRICS 57
7.3.3 NEONATES 57
7.4 EXTRACORPOREAL CARDIOPULMONARY RESUSCITATION (ECPR) 58
7.4.1 NEONATES 60
7.4.2 PEDIATRICS 60
7.4.3 ADULTS 60

8 EXTRACORPOREAL MEMBRANE OXYGENATION MACHINE MARKET, BY REGION 61

8.1 INTRODUCTION 62
8.2 NORTH AMERICA 64
8.2.1 U.S. 66
8.2.1.1 Rising healthcare spending 66
8.2.1.2 Rise in geriatric population, prevalence of cardiovascular diseases 66
8.2.1.3 Increase in research studies 66
8.2.2 CANADA 68
8.2.2.1 Implementation of a new funding model in Canadian hospitals 68
8.2.2.2 Conferences to increase awareness 68
8.3 EUROPE 70
8.3.1 GERMANY 72
8.3.1.1 Increasing volume of ECMO procedures in Germany 72
8.3.2 U.K. 73
8.3.2.1 Rising adoption of ECMO procedures 73
8.3.3 FRANCE 74
8.3.3.1 Rising healthcare spending 74
8.3.4 REST OF EUROPE 75
8.3.4.1 Decreasing number of cardiovascular deaths in Spain 75
8.3.4.2 Rising risk of diseases in Sweden 75
8.4 ASIA-PACIFIC 77
8.4.1 JAPAN 79
8.4.1.1 Favorable reimbursement scenario 79
8.4.2 CHINA 80
8.4.2.1 Rising geriatric population, CVD prevalence 80
8.4.3 INDIA 81
8.4.3.1 Growing applications and rising adoption of ECMO 81
8.4.4 REST OF ASIA-PACIFIC 82
8.4.4.1 Prevalence of cardiovascular and respiratory diseases in Australia 82
8.5 REST OF THE WORLD 84
8.5.1.1 Rising adoption of ECMO as a bridge to heart and lung transplantation in Brazil 85
8.5.1.2 Conferences in UAE to increase awareness 85

9 COMPETITIVE LANDSCAPE 87

9.1 OVERVIEW 87
9.2 MARKET SHARE ANALYSIS 88
9.2.1 GETINGE GROUP 88
9.2.2 MEDTRONIC PLC 89
9.2.3 LIVANOVA PLC 89
9.3 COMPETITIVE SITUATION AND TRENDS 90
9.3.1 APPROVALS 91
9.3.2 PRODUCT LAUNCHES 92
9.3.3 AGREEMENTS & PARTNERSHIPS 93
9.3.4 EXPANSIONS 94
9.3.5 OTHER STRATEGIES 95
 

10 COMPANY PROFILES 96

(Company at a Glance, Recent Financials, Products & Services, Strategies & Insights, & Recent Developments)*
10.1 INTRODUCTION 96
10.2 GETINGE GROUP 97
10.3 MEDTRONIC PLC 99
10.4 LIVANOVA PLC 102
10.5 TERUMO CORPORATION 105
10.6 XENIOS AG (ACQUIRED BY FRESENIUS MEDICAL CARE AG & CO. KGAA) 108
10.7 MICROPORT SCIENTIFIC CORPORATION 110
10.8 NIPRO CORPORATION 112
10.9 ORIGEN BIOMEDICAL, INC. 114
10.10 ALUNG TECHNOLOGIES, INC. 115
10.11 EUROSETS S.R.L. 117
*Details on company at a glance, recent financials, products & services, strategies & insights, & recent developments might not be captured in case of unlisted companies.
11 APPENDIX 119

LIST OF TABLES

TABLE 1 AVERAGE COST OF ECMO IN VARIOUS COUNTRIES 40
TABLE 2 INDICATIVE LIST OF TRAINING PROGRAMS FOR ECMO BY HOSPITALS 41
TABLE 3 EXTRACORPOREAL MEMBRANE OXYGENATION MACHINE MARKET SIZE,
BY MODALITY, 2014–2021 (USD MILLION) 43
TABLE 4 VENOVENOUS ECMO MACHINE MARKET SIZE, BY REGION,
2014–2021 (USD MILLION) 44
TABLE 5 NORTH AMERICA: VENOVENOUS ECMO MACHINE MARKET SIZE,
BY COUNTRY, 2014–2021 (USD MILLION) 44
TABLE 6 EUROPE: VENOVENOUS ECMO MACHINE MARKET SIZE, BY COUNTRY/REGION, 2014–2021 (USD MILLION) 44
TABLE 7 ASIA-PACIFIC: VENOVENOUS ECMO MACHINE MARKET SIZE, BY COUNTRY/REGION, 2014–2021 (USD MILLION) 45
TABLE 8 VENOARTERIAL ECMO MACHINE MARKET SIZE, BY REGION,
2014–2021 (USD MILLION) 45
TABLE 9 NORTH AMERICA: VENOARTERIAL ECMO MACHINE MARKET SIZE,
BY COUNTRY, 2014–2021 (USD MILLION) 46
TABLE 10 EUROPE: VENOARTERIAL ECMO MACHINE MARKET SIZE, BY COUNTRY/REGION, 2014–2021 (USD MILLION) 46
TABLE 11 ASIA-PACIFIC: VENOARTERIAL ECMO MACHINE MARKET SIZE,
BY COUNTRY/REGION, 2014–2021 (USD MILLION) 46
TABLE 12 ARTERIOVENOUS ECMO MACHINE MARKET SIZE, BY REGION,
2014–2021 (USD MILLION) 47
TABLE 13 NORTH AMERICA: ARTERIOVENOUS ECMO MACHINE MARKET SIZE,
BY COUNTRY, 2014–2021 (USD MILLION) 47
TABLE 14 EUROPE: ARTERIOVENOUS ECMO MACHINE MARKET SIZE, BY COUNTRY,
2014–2021 (USD MILLION) 48
TABLE 15 ASIA-PACIFIC: ARTERIOVENOUS ECMO MACHINE MARKET SIZE,
BY COUNTRY/REGION, 2014–2021 (USD MILLION) 48
TABLE 16 EXTRACORPOREAL MEMBRANE OXYGENATION MACHINE MARKET SIZE,
BY APPLICATION, 2014–2021 (USD MILLION) 50
TABLE 17 ECMO MACHINE MARKET SIZE FOR RESPIRATORY APPLICATIONS, BY REGION, 2014–2021 (USD MILLION) 51
TABLE 18 NORTH AMERICA: ECMO MACHINE MARKET SIZE FOR RESPIRATORY APPLICATIONS, BY COUNTRY , 2014–2021 (USD MILLION) 51
TABLE 19 EUROPE: ECMO MACHINE MARKET SIZE FOR RESPIRATORY APPLICATIONS,
BY REGION, 2014–2021 (USD MILLION) 52
TABLE 20 ASIA-PACIFIC: ECMO MACHINE MARKET SIZE FOR RESPIRATORY APPLICATIONS,
BY REGION, 2014–2021 (USD MILLION) 52
TABLE 21 ECMO MACHINE MARKET SIZE FOR RESPIRATORY APPLICATIONS, BY TYPE,
2014–2021 (USD MILLION) 52
TABLE 22 NEONATES RECEIVING ECMO SUPPORT FOR RESPIRATORY APPLICATIONS 53
TABLE 23 PEDIATRIC PATIENTS RECEIVING ECMO SUPPORT FOR RESPIRATORY APPLICATIONS 53
TABLE 24 LUNG TRANSPLANTS IN ADULTS ( BETWEEN JANUARY 1995 AND JUNE 2015) 54
TABLE 25 ADULTS RECEIVING ECMO SUPPORT FOR RESPIRATORY APPLICATIONS 54
TABLE 26 ECMO MACHINE MARKET SIZE FOR CARDIAC APPLICATIONS, BY REGION,
2014–2021 (USD MILLION) 55
TABLE 27 NORTH AMERICA: ECMO MACHINE MARKET SIZE FOR CARDIAC APPLICATIONS,
BY COUNTRY, 2014–2021 (USD MILLION) 55
TABLE 28 EUROPE: ECMO MACHINE MARKET FOR CARDIAC APPLICATIONS,
BY COUNTRY/REGION, 2014–2021 (USD MILLION) 56
TABLE 29 ASIA-PACIFIC: ECMO MACHINE MARKET SIZE FOR CARDIAC APPLICATIONS,
BY COUNTRY/REGION, 2014–2021 (USD MILLION) 56
TABLE 30 ECMO MACHINE MARKET SIZE FOR CARDIAC APPLICATIONS, BY TYPE,
2014–2021 (USD MILLION) 56
TABLE 31 ADULTS RECEIVING ECMO SUPPORT FOR CARDIAC APPLICATIONS 57
TABLE 32 PEDIATRIC PATIENTS RECEIVING ECMO SUPPORT FOR CARDIAC APPLICATIONS 57
TABLE 33 NEONATES RECEIVING ECMO SUPPORT FOR CARDIAC APPLICATIONS 58
TABLE 34 ECMO MACHINE MARKET SIZE FOR ECPR APPLICATIONS, BY REGION,
2014–2021 (USD MILLION) 58
TABLE 35 NORTH AMERICA: ECMO MACHINE MARKET SIZE FOR ECPR APPLICATIONS,
BY COUNTRY, 2014–2021 (USD MILLION) 59
TABLE 36 EUROPE: ECMO MACHINE MARKET SIZE FOR ECPR APPLICATIONS,
BY COUNTRY/REGION, 2014–2021 (USD MILLION) 59
TABLE 37 ASIA-PACIFIC: ECMO MACHINE MARKET SIZE FOR ECPR APPLICATIONS,
BY COUNTRY/REGION, 2014–2021 (USD MILLION) 59
TABLE 38 ECMO MARKET SIZE FOR ECPR APPLICATIONS, BY TYPE,
2014–2021 (USD MILLION) 60
TABLE 39 ECMO MACHINE MARKET SIZE, BY REGION, 2014-2021 (USD MILLION) 63
TABLE 40 NORTH AMERICA: ECMO MACHINE MARKET SIZE, BY COUNTRY,
2014-2021 (USD MILLION) 65
TABLE 41 NORTH AMERICA: ECMO MACHINE MARKET SIZE, BY MODALITY,
2014-2021 (USD MILLION) 65
TABLE 42 NORTH AMERICA: ECMO MACHINE MARKET SIZE, BY APPLICATION,
2014-2021 (USD MILLION) 65
TABLE 43 INDICATIVE LIST OF RESEARCH ARTICLES PUBLISHED IN THE U.S. 67
TABLE 44 U.S.: ECMO MACHINE MARKET SIZE, BY MODALITY, 2014-2021 (USD MILLION) 67
TABLE 45 U.S.: ECMO MACHINE MARKET SIZE, BY APPLICATION, 2014-2021 (USD MILLION) 68
TABLE 46 CANADA: ECMO MACHINE MARKET SIZE, BY MODALITY, 2014-2021 (USD MILLION) 69
TABLE 47 CANADA: ECMO MACHINE MARKET SIZE, BY APPLICATION,
2014-2021 (USD MILLION) 69
TABLE 48 EUROPE: ECMO MACHINE MARKET SIZE, BY COUNTRY, 2014-2021 (USD MILLION) 71
TABLE 49 EUROPE: ECMO MACHINE MARKET SIZE, BY MODALITY, 2014-2021 (USD MILLION) 71
TABLE 50 EUROPE: ECMO MACHINE MARKET SIZE, BY APPLICATION,
2014-2021 (USD MILLION) 71
TABLE 51 GERMANY: ECMO MACHINE MARKET SIZE, BY MODALITY,
2014-2021 (USD MILLION) 72
TABLE 52 GERMANY: ECMO MACHINE MARKET SIZE, BY APPLICATION,
2014-2021 (USD MILLION) 72
TABLE 53 U.K.: ECMO MACHINE MARKET SIZE, BY MODALITY, 2014-2021 (USD MILLION) 73
TABLE 54 U.K.: ECMO MACHINE MARKET SIZE, BY APPLICATION, 2014-2021 (USD MILLION) 73
TABLE 55 FRANCE: ECMO MACHINE MARKET SIZE, BY MODALITY, 2014-2021 (USD MILLION) 74
TABLE 56 FRANCE: ECMO MACHINE MARKET SIZE, BY APPLICATION,
2014-2021 (USD MILLION) 74
TABLE 57 ROE: ECMO MACHINE MARKET SIZE, BY MODALITY, 2014-2021 (USD MILLION) 75
TABLE 58 ROE: ECMO MACHINE MARKET SIZE, BY APPLICATION, 2014-2021 (USD MILLION) 76
TABLE 59 ASIA-PACIFIC: ECMO MACHINE MARKET SIZE, BY COUNTRY,
2014-2021 (USD MILLION) 78
TABLE 60 ASIA-PACIFIC: ECMO MACHINE MARKET SIZE, BY MODALITY,
2014-2021 (USD MILLION) 78
TABLE 61 ASIA-PACIFIC: ECMO MACHINE MARKET SIZE, BY APPLICATION,
2014-2021 (USD MILLION) 78
TABLE 62 JAPAN: ECMO MACHINE MARKET SIZE, BY MODALITY, 2014-2021 (USD MILLION) 79
TABLE 63 JAPAN: ECMO MACHINE MARKET SIZE, BY APPLICATION,
2014-2021 (USD MILLION) 79
TABLE 64 CHINA: ECMO MACHINE MARKET SIZE, BY MODALITY, 2014-2021 (USD MILLION) 80
TABLE 65 CHINA: ECMO MACHINE MARKET SIZE, BY APPLICATION,
2014-2021 (USD MILLION) 80
TABLE 66 INDICATIVE LIST OF HOSPITALS PROVIDING ECMO TREATMENT 81
TABLE 67 INDIA: ECMO MACHINE MARKET SIZE, BY MODALITY, 2014-2021 (USD MILLION) 81
TABLE 68 INDIA: ECMO MACHINE MARKET SIZE, BY APPLICATION, 2014-2021 (USD MILLION) 82
TABLE 69 ROAPAC: ECMO MACHINE MARKET SIZE, BY MODALITY, 2014-2021 (USD MILLION) 82
TABLE 70 ROAPAC: ECMO MACHINE MARKET SIZE, BY APPLICATION,
2014-2021 (USD MILLION) 83
TABLE 71 INDICATIVE LIST OF CONFERENCES RELATED TO ECMO 85
TABLE 72 ROW: ECMO MACHINE MARKET SIZE, BY MODALITY, 2014-2021 (USD MILLION) 85
TABLE 73 ROW: ECMO MACHINE MARKET SIZE, BY APPLICATION, 2014-2021 (USD MILLION) 86
TABLE 74 APPROVALS, 2013–2016 91
TABLE 75 PRODUCT LAUNCHES, 2013–2016 92
TABLE 76 AGREEMENTS & PARTNERSHIPS, 2013–2016 93
TABLE 77 EXPANSIONS, 2013–2016 94
TABLE 78 OTHER STRATEGIES, 2013–2016 95

LIST OF FIGURES

FIGURE 1 ECMO MACHINE MARKET SEGMENTATION 15
FIGURE 2 EXTRACORPOREAL MEMBRANE OXYGENATION (ECMO) MACHINE MARKET: RESEARCH METHODOLOGY STEPS 17
FIGURE 3 MARKET SIZE ESTIMATION METHODOLOGY: BOTTOM-UP APPROACH 23
FIGURE 4 MARKET SIZE ESTIMATION METHODOLOGY: TOP-DOWN APPROACH 24
FIGURE 5 RESEARCH DESIGN 25
FIGURE 6 DATA TRIANGULATION METHODOLOGY 26
FIGURE 7 VENOVENOUS SEGMENT DOMINATES THE ECMO MACHINE MARKET,
BY MODALITY, IN 2016 28
FIGURE 8 RESPIRATORY APPLICATIONS SEGMENT ACCOUNTS FOR THE LARGEST SHARE OF THE ECMO MACHINE MARKET IN 2016 29
FIGURE 9 ASIA-PACIFIC TO REGISTER THE HIGHEST CAGR DURING THE FORECAST PERIOD 30
FIGURE 10 ASIA-PACIFIC OFFERS SIGNIFICANT GROWTH OPPORTUNITIES FOR PLAYERS IN THE ECMO MACHINE MARKET 32
FIGURE 11 VENOVENOUS SEGMENT TO DOMINATE THE ECMO MACHINE MARKET IN 2016 33
FIGURE 12 RESPIRATORY APPLICATIONS WILL CONTINUE TO DOMINATE THE ECMO MACHINE MARKET IN 2021 34
FIGURE 13 ASIA-PACIFIC TO REGISTER THE HIGHEST CAGR DURING THE FORECAST PERIOD 34
FIGURE 14 EXTRACORPOREAL MEMBRANE OXYGENATION (ECMO) MACHINE MARKET: DRIVERS, RESTRAINTS, OPPORTUNITIES, AND CHALLENGES 36
FIGURE 15 NUMBER OF DEATHS FROM CARDIOVASCULAR AND RESPIRATORY DISEASES ACROSS THE GLOBE, 2000 VS. 2012 (THOUSAND INDIVIDUALS) 37
FIGURE 16 GLOBAL INCREASE IN THE NUMBER OF ECMO CENTERS 38
FIGURE 17 NORTH AMERICA TO COMMAND THE LARGEST SHARE OF THE MARKET IN 2016 62
FIGURE 18 NORTH AMERICA: MARKET SNAPSHOT 64
FIGURE 19 EUROPE: MARKET SNAPSHOT 70
FIGURE 20 ASIA-PACIFIC: MARKET SNAPSHOT 77
FIGURE 21 REST OF THE WORLD (ROW): MARKET SNAPSHOT 84
FIGURE 22 ECMO MACHINE MARKET SHARE, BY KEY PLAYER, 2015 87
FIGURE 23 KEY DEVELOPMENTS IN THE ECMO MACHINE MARKET, 2013–2016 90
FIGURE 24 BATTLE FOR MARKET SHARE: PRODUCT APPROVALS ACCOUNTED FOR THE LARGEST SHARE OF THE TOTAL DEVELOPMENTS REGISTERED BETWEEN
2013 & 2016 90
FIGURE 25 GEOGRAPHIC REVENUE MIX OF THE PROMINENT PLAYERS IN THE ECMO MACHINE MARKET 96
FIGURE 26 GETINGE GROUP: COMPANY SNAPSHOT (2015) 97
FIGURE 27 MEDTRONIC PLC: COMPANY SNAPSHOT (2015) 99
FIGURE 28 LIVANOVA PLC: COMPANY SNAPSHOT (2014) 102
FIGURE 29 TERUMO CORPORATION: COMPANY SNAPSHOT (2015) 105
FIGURE 30 MICROPORT SCIENTIFIC CORPORATION: COMPANY SNAPSHOT (2015) 110
FIGURE 31 NIPRO CORPORATION: COMPANY SNAPSHOT (2015) 112

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