Stem Cell Manufacturing Market by Product (HSCs, MSCs, iPSCs, ESCs, Instruments, Media, Consumables), Application (Research, Target Identification, Therapy (Autologous, Allogeneic), Cell Banks), End User (Pharma, Hospitals) - Global Forecast to 2023

Table of Contents

1 INTRODUCTION 13

1.1 OBJECTIVES OF THE STUDY 13
1.2 MARKET DEFINITION 13
1.2.1 MARKETS COVERED 14
1.2.2 GEOGRAPHIC SCOPE 15
1.2.3 YEARS CONSIDERED FOR THE STUDY 15
1.3 CURRENCY USED 16
1.4 MARKET STAKEHOLDERS 16

2 RESEARCH METHODOLOGY 17

2.1 RESEARCH DATA 17
2.1.1 SECONDARY DATA 18
2.1.1.1 Secondary sources 19
2.1.2 PRIMARY DATA 20
2.1.2.1 Breakdown of primaries 20
2.1.2.2 Key data from primary sources 21
2.2 MARKET SIZE ESTIMATION 22
2.2.1 BOTTOM-UP APPROACH 22
2.2.2 TOP-DOWN APPROACH 23
2.3 MARKET BREAKDOWN AND DATA TRIANGULATION 24
2.4 RESEARCH ASSUMPTIONS 25
2.5 RESEARCH LIMITATIONS 25

3 EXECUTIVE SUMMARY 26

4 PREMIUM INSIGHTS 30
4.1 STEM CELL MANUFACTURING: MARKET OVERVIEW (2018) 30
4.2 GLOBAL STEM CELL MANUFACTURING MARKET, BY PRODUCT, 2018 31
4.3 STEM CELL MANUFACTURING MARKET, BY APPLICATION AND REGION (2018) 32
4.4 STEM CELL MANUFACTURING MARKET, BY END USER (2018 VS 2023) 33
4.5 GEOGRAPHIC SNAPSHOT: STEM CELL MANUFACTURING MARKET (2017) 34

5 MARKET OVERVIEW 35

5.1 INTRODUCTION 35
5.2 MARKET DYNAMICS 35
5.2.1 MARKET DRIVERS 36
5.2.1.1 Growing public-private investments and funding in stem cell-based research 36
5.2.1.2 Growing public awareness about the therapeutic potency of stem cell products 36
5.2.1.3 Development of advanced genomic analysis techniques for quality control during stem cell manufacturing 37
5.2.1.4 Technological advancements in stem cell manufacturing and preservation 38
5.2.1.5 Evolving regulatory frameworks for stem cell therapeutics in the US and Europe 39
5.2.2 MARKET RESTRAINTS 40
5.2.2.1 Significant operational costs associated with stem cell manufacturing and banking 40
5.2.3 MARKET OPPORTUNITIES 41
5.2.3.1 Increased market focus on embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) 41
5.2.3.2 Supportive government regulations across developing countries 41
5.2.4 MARKET CHALLENGES 42
5.2.4.1 Technical limitations associated with manufacturing scale-up 42
5.2.4.2 Socio-ethical concerns related to the use of allogenic and human embryonic stem cells 43
5.2.5 RESEARCH PIPELINE ANALYSIS: STEM CELL-BASED PRODUCTS/THERAPIES 43

6 STEM CELL MANUFACTURING MARKET, BY PRODUCT 48

6.1 INTRODUCTION 49
6.2 STEM CELL LINES 50
6.2.1 INDUCED PLURIPOTENT STEM CELLS 51
6.2.2 EMBRYONIC STEM CELLS 53
6.2.3 MULTIPOTENT ADULT PROGENITOR STEM CELLS 54
6.2.4 MESENCHYMAL STEM CELLS 54
6.2.5 HEMATOPOIETIC STEM CELLS 55
6.2.6 NEURAL STEM CELLS 56
6.3 INSTRUMENTS 57
6.3.1 BIOREACTORS AND INCUBATORS 58
6.3.2 CELL SORTERS 58
6.3.3 OTHER INSTRUMENTS 59
6.4 CULTURE MEDIA 60
6.5 CONSUMABLES 61

7 STEM CELL MANUFACTURING MARKET, BY APPLICATION 62

7.1 INTRODUCTION 63
7.2 RESEARCH APPLICATIONS 64
7.2.1 DRUG DISCOVERY AND DEVELOPMENT 65
7.2.2 LIFE SCIENCE RESEARCH 66
7.3 CLINICAL APPLICATIONS 67
7.3.1 ALLOGENIC STEM CELL THERAPY 68
7.3.2 AUTOLOGOUS STEM CELL THERAPY 69
7.4 CELL AND TISSUE BANKING 70

8 STEM CELL MANUFACTURING MARKET, BY END USER 72

8.1 INTRODUCTION 73
8.2 PHARMACEUTICAL AND BIOTECHNOLOGY COMPANIES 74
8.3 HOSPITALS AND SURGICAL CENTERS 75
8.4 ACADEMIC INSTITUTES, RESEARCH LABORATORIES, AND CROS 76
8.5 CELL BANKS AND TISSUE BANKS 77
8.6 OTHER END USERS 78

9 STEM CELL MANUFACTURING MARKET, BY REGION 79

9.1 INTRODUCTION 80
9.2 NORTH AMERICA 81
9.2.1 US 86
9.3 EUROPE 87
9.4 ASIA PACIFIC 92
9.5 REST OF THE WORLD 97

10 COMPETITIVE LANDSCAPE 102

10.1 OVERVIEW 102
10.2 MARKET RANKING (2016) 102
10.3 COMPETITIVE SCENARIO 103
10.3.1 PRODUCT LAUNCHES, UPGRADES, AND APPROVALS 104
10.3.2 AGREEMENTS, PARTNERSHIPS, AND COLLABORATIONS 104
10.3.3 ACQUISITIONS 105
10.3.4 EXPANSIONS 106

11 COMPANY PROFILES 107

(Introduction, Products & Services, Strategy, & Analyst Insights, Developments, MnM View)*
11.1 MERCK GROUP 107
11.2 THERMO FISHER SCIENTIFIC 112
11.3 BECTON, DICKINSON AND COMPANY (BD) 121
11.4 BIO-RAD LABORATORIES 125
11.5 MILTENYI BIOTEC 129
11.6 PHARMICELL 133
11.7 TAKARA BIO GROUP 134
11.8 STEMCELL TECHNOLOGIES 139
11.9 OSIRIS THERAPEUTICS 144
11.10 ANTEROGEN 146
11.11 CELLULAR DYNAMICS INTERNATIONAL (SUBSIDIARY OF FUJIFILM HOLDINGS CORPORATION) 147
11.12 MEDIPOST 151
11.13 LONZA GROUP 153
11.14 HOLOSTEM TERAPIE AVANZATE 156
11.15 PLURISTEM THERAPEUTICS 157

*Details on MarketsandMarkets view, Introduction, Product & Services, Strategy, & Analyst Insights, New Developments might not be captured in case of unlisted companies.
12 APPENDIX 160

LIST OF TABLES

TABLE 1 KEY GENOME-BASED CELL ANALYSIS PRODUCTS LAUNCHED DURING 2014–2017 37
TABLE 2 GLOBAL STEM CELL MANUFACTURING MARKET, BY PRODUCT,
2016-2023 (USD MILLION) 49
TABLE 3 GLOBAL STEM CELL MANUFACTURING MARKET FOR STEM CELL LINES,
BY TYPE, 2016-2023 (USD MILLION) 50
TABLE 4 STEM CELL MANUFACTURING MARKET FOR STEM CELL LINES,
BY REGION, 2016-2023 (USD MILLION) 51
TABLE 5 KEY EXPANSION AND DIFFERENTIATION TECHNOLOGIES TO EXTRACT HUMAN-INDUCED PLURIPOTENT STEM CELL LINES 51
TABLE 6 INDUCED PLURIPOTENT STEM CELLS MARKET, BY REGION,
2016-2023 (USD MILLION) 53
TABLE 7 EMBRYONIC STEM CELLS MARKET, BY REGION, 2016-2023 (USD MILLION) 53
TABLE 8 MULTIPOTENT ADULT PROGENITOR STEM CELLS MARKET, BY REGION,
2016-2023 (USD MILLION) 54
TABLE 9 MESENCHYMAL STEM CELLS MARKET, BY REGION, 2016-2023 (USD MILLION) 55
TABLE 10 HEMATOPOIETIC STEM CELLS MARKET, BY REGION, 2016-2023 (USD MILLION) 56
TABLE 11 NEURAL STEM CELLS MARKET, BY REGION, 2016-2023 (USD MILLION) 56
TABLE 12 GLOBAL STEM CELL MANUFACTURING MARKET FOR INSTRUMENTS,
BY TYPE, 2016-2023 (USD MILLION) 57
TABLE 13 STEM CELL MANUFACTURING MARKET FOR INSTRUMENTS, BY REGION,
2016-2023 (USD MILLION) 57
TABLE 14 STEM CELL MANUFACTURING MARKET FOR BIOREACTORS & INCUBATORS,
BY REGION, 2016-2023 (USD MILLION) 58
TABLE 15 STEM CELL MANUFACTURING MARKET FOR CELL SORTERS, BY REGION,
2016-2023 (USD MILLION) 59
TABLE 16 STEM CELL MANUFACTURING MARKET FOR OTHER INSTRUMENTS,
BY REGION, 2016-2023 (USD MILLION) 59
TABLE 17 STEM CELL MANUFACTURING MARKET FORT CULTURE MEDIA,
BY REGION, 2016-2023 (USD MILLION) 60
TABLE 18 STEM CELL MANUFACTURING MARKET FOR CONSUMABLES,
BY REGION, 2016-2023 (USD MILLION) 61
TABLE 19 STEM CELL MANUFACTURING MARKET, BY APPLICATION,
2016–2023 (USD MILLION) 63
TABLE 20 STEM CELL MANUFACTURING MARKET FOR RESEARCH APPLICATIONS,
BY TYPE, 2016–2023 (USD MILLION) 64
TABLE 21 STEM CELL MANUFACTURING MARKET FOR RESEARCH APPLICATIONS,
BY REGION, 2016–2023 (USD MILLION) 65
TABLE 22 STEM CELL MANUFACTURING MARKET FOR DRUG DISCOVERY AND DEVELOPMENT, BY REGION, 2016–2023 (USD MILLION) 66
TABLE 23 STEM CELL MANUFACTURING MARKET FOR LIFE SCIENCE RESEARCH,
BY REGION, 2016–2023 (USD MILLION) 67
TABLE 24 STEM CELL MANUFACTURING MARKET FOR CLINICAL APPLICATIONS,
BY TYPE, 2016–2023 (USD MILLION) 67
TABLE 25 STEM CELL MANUFACTURING MARKET FOR CLINICAL APPLICATIONS,
BY REGION, 2016–2023 (USD MILLION) 68
TABLE 26 STEM CELL MANUFACTURING MARKET FOR ALLOGENIC STEM CELL THERAPY,
BY REGION, 2016–2023 (USD MILLION) 69
TABLE 27 STEM CELL MANUFACTURING MARKET FOR AUTOLOGOUS STEM CELL THERAPY, BY REGION, 2016–2023 (USD MILLION) 70
TABLE 28 STEM CELL MANUFACTURING MARKET FOR CELL & TISSUE BANKING,
BY REGION, 2016–2023 (USD MILLION) 71
TABLE 29 STEM CELL MANUFACTURING MARKET, BY END USER, 2016–2023 (USD MILLION) 73
TABLE 30 STEM CELL MANUFACTURING MARKET FOR PHARMACEUTICAL AND BIOTECHNOLOGY COMPANIES, BY REGION, 2016–2023 (USD MILLION) 74
TABLE 31 STEM CELL MANUFACTURING MARKET FOR HOSPITALS AND SURGICAL CENTERS, BY REGION, 2016–2023 (USD MILLION) 75
TABLE 32 STEM CELL MANUFACTURING MARKET FOR ACADEMIC INSTITUTES, RESEARCH LABORATORIES, AND CROS, BY REGION, 2016–2023 (USD MILLION) 76
TABLE 33 STEM CELL MANUFACTURING MARKET FOR CELL BANKS AND TISSUE BANKS,
BY REGION, 2016–2023 (USD MILLION) 77
TABLE 34 STEM CELL MANUFACTURING MARKET FOR OTHER END USERS, BY REGION, 2016–2023 (USD MILLION) 78
TABLE 35 STEM CELL MANUFACTURING MARKET, BY REGION, 2016–2023 (USD MILLION) 81
TABLE 36 NORTH AMERICA: STEM CELL MANUFACTURING MARKET, BY PRODUCT,
2016–2023 (USD MILLION) 83
TABLE 37 NORTH AMERICA: STEM CELL MANUFACTURING MARKET FOR STEM CELL LINES, BY TYPE, 2016–2023 (USD MILLION) 83
TABLE 38 NORTH AMERICA: STEM CELL MANUFACTURING MARKET FOR INSTRUMENTS,
BY TYPE, 2016–2023 (USD MILLION) 84
TABLE 39 NORTH AMERICA: STEM CELL MANUFACTURING MARKET, BY APPLICATION,
2016–2023 (USD MILLION) 84
TABLE 40 NORTH AMERICA: STEM CELL MANUFACTURING MARKET FOR RESEARCH APPLICATIONS, BY TYPE, 2016–2023 (USD MILLION) 84
TABLE 41 NORTH AMERICA: STEM CELL MANUFACTURING MARKET FOR CLINICAL APPLICATIONS, BY TYPE, 2016–2023 (USD MILLION) 85
TABLE 42 NORTH AMERICA: STEM CELL MANUFACTURING MARKET, BY END USER,
2016–2023 (USD MILLION) 85
TABLE 43 US: STEM CELL MANUFACTURING MARKET, BY PRODUCT,
2016–2023 (USD MILLION) 86
TABLE 44 US: STEM CELL MANUFACTURING MARKET FOR STEM CELL LINES,
BY TYPE, 2016–2023 (USD MILLION) 86
TABLE 45 EUROPE: STEM CELL MANUFACTURING MARKET, BY PRODUCT,
2016–2023 (USD MILLION) 89
TABLE 46 EUROPE: STEM CELL MANUFACTURING MARKET FOR STEM CELL LINES,
BY TYPE, 2016–2023 (USD MILLION) 89
TABLE 47 EUROPE: STEM CELL MANUFACTURING MARKET FOR INSTRUMENTS,
BY TYPE, 2016–2023 (USD MILLION) 90
TABLE 48 EUROPE: STEM CELL MANUFACTURING MARKET, BY APPLICATION,
2016–2023 (USD MILLION) 90
TABLE 49 EUROPE: STEM CELL MANUFACTURING MARKET FOR RESEARCH APPLICATIONS, BY TYPE, 2016–2023 (USD MILLION) 90
TABLE 50 EUROPE: STEM CELL MANUFACTURING MARKET FOR CLINICAL APPLICATIONS,
BY TYPE, 2016–2023 (USD MILLION) 91
TABLE 51 EUROPE: STEM CELL MANUFACTURING MARKET, BY END USER,
2016–2023 (USD MILLION) 91
TABLE 52 ASIA PACIFIC: STEM CELL MANUFACTURING MARKET, BY PRODUCT,
2016–2023 (USD MILLION) 94
TABLE 53 ASIA PACIFIC: STEM CELL MANUFACTURING MARKET FOR STEM CELL LINES,
BY TYPE, 2016–2023 (USD MILLION) 94
TABLE 54 ASIA PACIFIC: STEM CELL MANUFACTURING MARKET FOR INSTRUMENTS,
BY TYPE, 2016–2023 (USD MILLION) 95
TABLE 55 ASIA PACIFIC: STEM CELL MANUFACTURING MARKET, BY APPLICATION,
2016–2023 (USD MILLION) 95
TABLE 56 ASIA PACIFIC: STEM CELL MANUFACTURING MARKET FOR RESEARCH APPLICATIONS, BY TYPE, 2016–2023 (USD MILLION) 95
TABLE 57 ASIA PACIFIC: STEM CELL MANUFACTURING MARKET FOR CLINICAL APPLICATIONS, BY TYPE, 2016–2023 (USD MILLION) 96
TABLE 58 ASIA PACIFIC: STEM CELL MANUFACTURING MARKET, BY END USER,
2016–2023 (USD MILLION) 96
TABLE 59 ROW: STEM CELL MANUFACTURING MARKET, BY PRODUCT,
2016–2023 (USD MILLION) 99
TABLE 60 ROW: STEM CELL MANUFACTURING MARKET FOR STEM CELL LINES,
BY TYPE, 2016–2023 (USD MILLION) 99
TABLE 61 ROW: STEM CELL MANUFACTURING MARKET FOR INSTRUMENTS,
BY TYPE, 2016–2023 (USD MILLION) 100
TABLE 62 ROW: STEM CELL MANUFACTURING MARKET, BY APPLICATION,
2016–2023 (USD MILLION) 100
TABLE 63 ROW: STEM CELL MANUFACTURING MARKET FOR RESEARCH APPLICATIONS,
BY TYPE, 2016–2023 (USD MILLION) 100
TABLE 64 ROW: STEM CELL MANUFACTURING MARKET FOR CLINICAL APPLICATIONS,
BY TYPE, 2016–2023 (USD MILLION) 101
TABLE 65 ROW: STEM CELL MANUFACTURING MARKET, BY END USER,
2016–2023 (USD MILLION) 101
TABLE 66 KEY PRODUCT LAUNCHES, UPGRADES, AND APPROVALS, 2014–2017 104
TABLE 67 KEY AGREEMENTS, PARTNERSHIPS, AND COLLABORATIONS, 2014–2017 104
TABLE 68 KEY ACQUISITIONS, 2014–2017 105
TABLE 69 KEY EXPANSIONS, 2014–2017 106
 

LIST OF FIGURES

FIGURE 1 GLOBAL STEM CELL MANUFACTURING MARKET: RESEARCH METHODOLOGY STEPS 17
FIGURE 2 RESEARCH DESIGN 18
FIGURE 3 STEM CELL MANUFACTURING MARKET: BOTTOM-UP APPROACH 22
FIGURE 4 STEM CELL MANUFACTURING MARKET: TOP-DOWN APPROACH 23
FIGURE 5 DATA TRIANGULATION METHODOLOGY 24
FIGURE 6 CULTURE MEDIA SEGMENT TO DOMINATE THE GLOBAL STEM CELL MANUFACTURING MARKET DURING FORECAST PERIOD 26
FIGURE 7 RESEARCH APPLICATIONS SEGMENT TO DOMINATE THE STEM CELL MANUFACTURING MARKET DURING FORECAST PERIOD 27
FIGURE 8 CELL AND TISSUE BANKS TO BE THE FASTEST-GROWING END-USER SEGMENT DURING 2018-2023 28
FIGURE 9 ASIA PACIFIC TO GROW AT THE HIGHEST RATE IN THE FORECAST PERIOD 29
FIGURE 10 RISING PUBLIC-PRIVATE INVESTMENTS AND FUNDING FOR STEM CELL-BASED RESEARCH TO DRIVE MARKET GROWTH 30
FIGURE 11 CULTURE MEDIA SEGMENT TO DOMINATE THE GLOBAL STEM CELL MANUFACTURING MARKET DURING THE FORECAST PERIOD 31
FIGURE 12 NORTH AMERICA TO DOMINATE THE STEM CELL MANUFACTURING MARKET,
BY APPLICATION, IN 2018 32
FIGURE 13 CELL BANKS AND TISSUE BANKS TO BE FASTEST-GROWING SEGMENT DURING THE FORECAST PERIOD 33
FIGURE 14 NORTH AMERICA TO DOMINATE THE GLOBAL STEM CELL MANUFACTURING MARKET DURING THE FORECAST PERIOD 34
FIGURE 15 STEM CELL MANUFCATURING MARKET: DRIVERS, RESTRAINTS, OPPORTUNITIES, AND CHALLENGES 35
FIGURE 16 STEM CELL LINES TO BE THE FASTEST-GROWING SEGMENT DURING 2018-2023 49
FIGURE 17 STEM CELL MANUFACTURING MARKET, BY APPLICATION, 2018 VS. 2023 63
FIGURE 18 STEM CELL MANUFACTURING MARKET, BY END USER, 2018 VS. 2023 73
FIGURE 19 GEOGRAPHIC SNAPSHOT: ASIA PACIFIC TO BE THE FASTEST GROWING REGION IN STEM CELL MANUFACTURING MARKET DURING THE FORECAST PERIOD 80
FIGURE 20 NORTH AMERICA: STEM CELL MANUFACTURING MARKET SNAPSHOT 82
FIGURE 21 EUROPE: STEM CELL MANUFACTURING MARKET SNAPSHOT 88
FIGURE 22 ASIA PACIFIC: STEM CELL MANUFACTURING MARKET SNAPSHOT 93
FIGURE 23 ROW: STEM CELL MANUFACTURING MARKET SNAPSHOT 98
FIGURE 24 GLOBAL STEM CELL MANUFACTURING MARKET RANKING ANALYSIS,
BY KEY PLAYERS (2016) 102
FIGURE 25 MERCK GROUP: COMPANY SNAPSHOT (2016) 107
FIGURE 26 THERMO FISHER SCIENTIFIC: COMPANY SNAPSHOT (2016) 112
FIGURE 27 BD: COMPANY SNAPSHOT (2017) 121
FIGURE 28 BIO-RAD LABORATORIES: COMPANY SNAPSHOT (2016) 125
FIGURE 29 TAKARA BIO GROUP: COMPANY SNAPSHOT (2017) 134
FIGURE 30 FUJIFILM HOLDINGS CORPORATION: COMPANY SNAPSHOT (2017) 147
FIGURE 31 MEDIPOST: COMPANY SNAPSHOT (2016) 151
FIGURE 32 LONZA GROUP: COMPANY SNAPSHOT (2016) 153
FIGURE 33 PLURISTEM THERAPEUTICS: COMPANY SNAPSHOT (2016) 157

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