Global Markets for Vaccine Technologies

Table of Contents

Chapter 1 Introduction

Study Goals and Objectives
Reasons for Doing This Study
Scope of Report
Methodology
Information Sources
Geographic Breakdown
Analyst's Credentials
BCC Custom Research
Related BCC Research Reports

Chapter 2 Summary and Highlights

Chapter 3 Market and Technology Background

Definitions
Immune System and Vaccines

• How Vaccines Work?
• Types of Immunity
• Advantages of Vaccination

History of Vaccines
Types of Vaccines

• Attenuated (Live) Vaccines
• Inactivated (Killed) Vaccines
• Toxoid Vaccines
• Subunit Vaccines
• Conjugate Vaccines
• Recombinant Vector Vaccines
• DNA Vaccines
• RNA Vaccines

Adjuvants and Excipients

• Pathogen Components
• Particulate Adjuvants

Infectious Diseases Preventable by Vaccines
Human Diseases

• Viral Diseases
• Bacterial Diseases

Animal Diseases

• Food-Producing Animals
• Companion Animals
• Other Animals

Rapid Manufacturing for Pandemics
Types of Vaccine Manufacturing Methods

• Plant-Based Vaccines
• Egg-Based Vaccine Manufacturing
• Cell-Based Vaccines

Investigational Vaccine Manufacturing Methods
Clinical Development of Vaccines
Clinical Development of Pandemic Vaccines

• Laws and Regulations

Vaccine Distribution in the Case of Pandemic Diseases
Government Initiatives
Recent Technologies and Companies
Technological Advancements Such as Rapid Manufacturing
Rising Immunization across the Globe
Government Support for Vaccine Development
Lack of Awareness in Low-Income Countries
Opportunities

• RNA Vaccination
• Rise of Antibiotic Resistance

Current Situation

• Dynamics of the Market for Human Vaccines
• Dynamics of the Market for Animal Vaccines

Regulatory Aspects

• World Health Organization (WHO) Prequalified Vaccines
• New Product Approvals
• Recalls
• Vaccine Shortage
• Significant Regulatory Developments in Vaccine-Preventable Disease Products

Chapter 4 Market Breakdown by Human Vaccine

Human Vaccines by Type

• Attenuated (Live) Vaccines
• Inactivated Vaccines
• Conjugate Vaccines
• DNA/rDNA Vaccines
• Subunit Vaccines
• Toxoid Vaccines
• Other/Combination Vaccines

Vaccines by Age Group

• Pediatric Vaccines
• Vaccines for Adolescents and Adults
• Vaccines for the Geriatric Population

Vaccine by Disease Type

• Diptheria
• Influenza
• Hepatitis A
• Measles
• Rotavirus
• Chickenpox
• Other Diseases and Combination Vaccines
• Outbreak of Diseases

Vaccines by Delivery Route

• Intramuscular Injection
• Intradermal Injection
• Mucosal Vaccination
• Nanopatch

Chapter 5 Market Breakdown by Animal Vaccine

Animal Vaccines

• Market by Type

Chapter 6 Market Breakdown by Region

North America

• United States
• Canada

Europe

• Germany
• France
• United Kingdom
• Italy
• Rest of Europe

Asia-Pacific

• China
• Japan
• India
• Rest of APAC

Rest of the World

Chapter 7 COVID-19 Impact on Present and Future

Impact of COVID-19 on Vaccine Supplies

• Massive Impact on Lower-Income Countries Threatens More Disease Outbreaks

Chapter 8 Company Profiles

ABBOTT LABORATORIES
ASTELLAS PHARMA INC.
ASTRAZENECA PLC
BAXTER INTERNATIONAL INC.
BAYER ANIMAL HEALTH
BHARAT BIOTECH INTERNATIONAL LTD.
BIOLOGICAL E. LTD.
BIO-MANGUINHOS
BIOPROPERTIES PTY LTD.
BOEHRINGER INGELHEIM GMBH
BUL BIO NATIONAL CENTER OF INFECTIOUS AND PARASITIC DISEASES LTD. (BB-NCIPD LTD.)
CADILA HEALTHCARE LTD. (ZYDUS CADILA)
CEVA SANTE ANIMALE
CHINA NATIONAL BIOTEC GROUP (CNBG)
COLORADO SERUM CO.
CSL LTD.
ELANCO ANIMAL HEALTH
EMERGENT BIOSOLUTIONS INC.
FATRO SPAVIA
GE HEALTHCARE
GENEONE LIFE SCIENCES INC.
PRECIGEN INC. (FORMERLY INTREXON)
GEOVAX
GLAXOSMITHKLINE PLC
GREEN CROSS CORP.
IBIO INC.
INSTITUT PASTEUR DE DAKAR
JOHNSON & JOHNSON INC.
LG LIFE SCIENCES
MAXCYTE INC.
MERCK & CO., INC.
NOVARTIS PHARMA AG
PANACEA BIOTEC LTD.
PFENEX INC.
PFIZER INC.
PROFECTUS BIOSCIENCES INC.
PT BIO FARMA
REPLIKINS LTD.
SANOFI PASTEUR
SERUM INSTITUTE OF INDIA LTD.
STATENS SERUM INSTITUT
THERMO FISHER SCIENTIFIC
VALNEVA SE
VIRBAC
ZOETIS INC.

List of Tables

Summary Table : Global Market for Vaccine Technologies, by Segment, Through 2025
Table 1 : History of Vaccines, by Year
Table 2 : Types of Attenuated (Live) Vaccines, by Segment
Table 3 : Advantages and Disadvantages of Attenuated (Live) Vaccines
Table 4 : Types of Inactivated (Killed) Vaccines, by Segment
Table 5 : Advantages and Disadvantages of Inactivated (Killed) Vaccines
Table 6 : Types of Toxoid Vaccines, by Segment
Table 7 : Advantages and Disadvantages of Toxoid Vaccines
Table 8 : Types of Subunit Vaccines, by Segment
Table 9 : Advantages and Disadvantages of Subunit Vaccines
Table 10 : Types of Conjugate Vaccines, by Segment
Table 11 : Advantages and Disadvantages of Conjugate Vaccines
Table 12 : Types of Recombinant Vector Vaccines, by Segment
Table 13 : Advantages and Disadvantages of Recombinant Vector Vaccines
Table 14 : Types of DNA Vaccines, by Segment
Table 15 : Advantages and Disadvantages of DNA Vaccines
Table 16 : Advantages and Disadvantages of RNA Vaccines
Table 17 : Vaccine Excipient and Media Summary, Excipients included in U.S. Vaccines
Table 18 : Vaccine-Preventable Human Viral Diseases
Table 19 : Vaccine-Preventable Human Bacterial Diseases
Table 20 : Vaccine-Preventable Parasitic Animal Diseases Found in Food-Producing Animals
Table 21 : Vaccine-Preventable Bacterial Animal Diseases Found in Food-Producing Animals
Table 22 : Vaccine-Preventable Viral Animal Diseases Found in Food-Producing Animals
Table 23 : Vaccine-Preventable Parasitic Animal Diseases Found in Companion Animals
Table 24 : Vaccine-Preventable Bacterial Animal Diseases Found in Companion Animals
Table 25 : Vaccine-Preventable Viral Animal Diseases Found in Companion Animals
Table 26 : Vaccine-Preventable Viral Animal Diseases Found in Other Animals
Table 27 : Vaccine-Preventable Viral Animal for Food-Producing in Companion
Table 28 : Cases of Diphtheria, by Country, 2011-2015
Table 29 : Petitions Filed, Compensated and Dismissed about Vaccinessince the Beginning of VICP, 1998-2020
Table 30 : WHO Prequalified Vaccines, January 2014-April 2020
Table 31 : Newly Approved Vaccines, January 2014-April 2020
Table 32 : Global Vaccine Recalls, by Manufacturer, January 2014-November 2017
Table 33 : Global Vaccine Shortage, by Manufacturer, January 2012-November 2017
Table 34 : Global Market for Human Vaccines, by Type, Through 2025
Table 35 : Global Market for Attenuated (Live) Vaccines, by Region, Through 2025
Table 36 : Global Market for Inactivated (Killed) Vaccines, by Region, Through 2025
Table 37 : Global Market for Conjugate Vaccines, by Region, Through 2025
Table 38 : Global Market for Recombinant/rDNA/DNA Vaccines, by Region, Through 2025
Table 39 : Global Market for Subunit Vaccines, by Region,Through 2025
Table 40 : Global Market for Toxoid Vaccines, by Region, Through 2025
Table 41 : Global Market for Other/Combination Vaccines, by Region, Through 2025
Table 42 : Global Market for Human Vaccines, by Age Group, Through 2025
Table 43 : Pediatric Vaccines Doses
Table 44 : Pediatric/VFC Vaccine Price List, 2019
Table 45 : Influenza Vaccine Price List, 2020
Table 46 : Pediatric Vaccines Doses, by Age Group
Table 47 : Global Market for Human Vaccines for Pediatrics, by Region, Through 2025
Table 48 : Global Market for Human Vaccines for Adults, by Region, Through 2025
Table 49 : Adult Vaccine Price List
Table 50 : Vaccine Price List for Geriatric Population
Table 51 : Global Market for Human Vaccines for Geriatrics, by Region, Through 2025
Table 52 : Vaccines, by Disease Type
Table 53 : Global Market for Human Vaccines, by Disease Type, Through 2025
Table 54 : Global Market for Meningococcal/Pneumococcal Vaccines, by Region, Through 2025
Table 55 : Global Market for Influenza Vaccines, by Region, Through 2025
Table 56 : Global Market for Pediatric Polio/Pertussis/Hib Vaccines, by Region, Through 2025
Table 57 : Global Market for Rotavirus Diseases Vaccines, by Region, Through 2025
Table 58 : Global Market for Endemic Diseases Vaccines, by Region, Through 2025
Table 59 : Global Market for HPV Vaccines, by Region, Through 2025
Table 60 : Global Market for Adult/Adolescent Booster Vaccines, by Region, Through 2025
Table 61 : Global Market for Other Diseases Vaccines, by Region, Through 2025
Table 62 : Seasonal Influenza Vaccines
Table 63 : Vaccine, by Route of Delivery
Table 64 : Site for Intramuscular Immunization, by Age
Table 65 : Nasal Vaccines, by Disease
Table 66 : Global Market for Animal Vaccines, by Type, Through 2025
Table 67 : Global Market for Food-Producing Animals Vaccines, by Region, Through 2025
Table 68 : Global Market for Companion Animals Vaccines, by Region, Through 2025
Table 69 : Global Market for Other Animal Vaccines, by Region, Through 2025
Table 70 : UNICEF Vaccination Price and Major Suppliers, 2020
Table 71 : Estimated Life Saved due to Vaccination, 2011-2020 (Assuming No Vaccination as the Counterfactual)
Table 72 : U.S. Recommended Immunization Schedule, by Vaccine Type, 2020
Table 73 : Vaccine Price List, 2019
Table 74 : Immunization Schedule of Canada, 2020
Table 75 : Immunization Schedule of Germany, 2020
Table 76 : Immunization Schedule of France, 2020
Table 77 : Vaccination and Immunization Schedule of the U.K., 2020
Table 78 : Immunization Schedule of Italy, 2020
Table 79 : Immunization Schedule of China, 2020
Table 80 : Immunization Schedule of Japan, 2020
Table 81 : Immunization Schedule of India, 2020
Table 82 : Number of Reported Cases in India, 2013-2016
Table 83 : GAVI Support to India, 2001-2021
Table 84 : Africa WHO/UNICEF Vaccination Coverage Estimate, 2014-2019
Table 85 : Middle East WHO/UNICEF Vaccination Coverage Estimate, 2014-2019
Table 86 : Global Market for Human Vaccines, by Region, Through 2025
Table 87 : Major COVID-19 Vaccine Candidates Under Development

List of Figures

Summary Figure : Global Market for Vaccine Technologies, by Segment, 2019-2025
Figure 1 : Literacy Rates in Population Above 15 Years of Age in Selected Countries, 2015
Figure 2 : Infants Lacking Immunization Measles, 2018
Figure 3 : Polio Cases in the U.S., 1950-2015
Figure 4 : Percentage of Children Aged 19-35 Months Receiving Vaccinations in the U.S., 2019
Figure 5 : Globally Immunization Coverage, 2019
Figure 6 : Seasonal Flu Vaccination Coverage in the U.S., 2013-2019
Figure 7 : Globally Immunization Coverage, 2013-2019
Figure 8 : Diphtheria Cases in the U.S., 1945-2015
Figure 9 : Seasonal Flu Vaccination Coverage in the U.S., 2013-2019
Figure 10 : WHO/UNICEF Vaccine Coverage Estimate, 2018 and 2019
Figure 11 : Hepatitis A Cases in the U.S., 1990-2019
Figure 12 : Measles Cases in the U.S., 1960-2019
Figure 13 : Chickenpox Cases in the U.S., 1975-2014
Figure 14 : Global Immunization Coverage, 2019
Figure 15 : Shares of Donor Contributions to GAVI Alliance, 2000-2020
Figure 16 : Global Investment in R&D Vaccination, 2012-2015
Figure 17 : Donation from the U.S. to GAVI Alliance, 2013-2018
Figure 18 : Canada's Cash Funding to GAVI Alliance, 2014-2018
Figure 19 : Germany's Funding to GAVI Alliance, 2013-2018
Figure 20 : France's Funding to GAVI Alliance, 2012-2015
Figure 21 : U.K.'s Funding to GAVI Alliance, 2000-2036
Figure 22 : Donations from European Governments and Organizations to GAVI, 2013-2018
Figure 23 : Investment by APAC Counties in Vaccination R&D, 2012-2019
Figure 24 : Shares of Chinese Funding to GAVI Alliance, 2001-2021
Figure 25 : Japan's Funding to GAVI Alliance, 2011-2020
Figure 26 : Australia's Funding to GAVI Alliance, 2013-2017

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